Applied Organometallic Chemistry,
Journal Year:
2025,
Volume and Issue:
39(3)
Published: Feb. 24, 2025
ABSTRACT
One
3D
Zn‐MOF
,
namely,
{[Zn
2
(L)(OH)(DMF)]}
n
was
selected
based
on
the
flexible
ether
oxygen
carboxylic
acid
3‐(3,5‐dicarboxylatobenzyloxy)benzoic
(H
3
L).
able
to
specifically
recognize
biomarker
methylmalonic
(MMA)
and
antibiotic
tetracycline
(TC)
through
fluorescence
enhancement
ratio
mechanism,
with
detection
limits
(LOD)
as
low
1.29
0.26
μM,
respectively.
It
also
has
high
selectivity
rapid
response
characteristics.
In
particular,
visual
significantly
enhanced
in
presence
of
Tb
3+
antenna
effect.
To
explore
potential
application,
fluorescent
test
strips
mixed
matrix
membrane
(MMM)
were
successfully
prepared
realize
detection.
The
recovery
rates
MMA
TC
simulated
urine
actual
water
systems
95.3%–100.5%
93.5%–94.7%,
respectively,
indicating
that
provided
possibility
for
detecting
practical
systems.
Metal–organic
frameworks
(MOFs)
have
emerged
as
innovative
nanozyme
mimics,
particularly
in
the
area
of
oxidase
catalysis,
outperforming
traditional
MOF-based
peroxidase
and
other
nanomaterial-based
systems.
This
review
explores
various
advantages
that
MOFs
offer
terms
catalytic
activity,
low-cost,
stability,
structural
versatility.
With
a
primary
focus
on
their
application
biochemical
sensing,
oxidases
demonstrated
remarkable
utility,
prompting
thorough
exploration
design
modification
strategies.
Moreover,
aims
to
provide
comprehensive
analysis
strategies
employed
rational
MOF
structures
optimize
key
parameters
such
sensitivity,
selectivity,
stability
context
sensors.
Through
an
exhaustive
examination
recent
research
developments,
this
article
seeks
insights
into
nuanced
interplay
between
performance,
shedding
light
mechanisms
underpin
effectiveness
mimics.
Finally,
addresses
challenges
opportunities
associated
with
aiming
drive
further
advancements
structure
development
highly
effective
sensors
for
diverse
applications.
Detecting
pathogenic
bacteria
is
crucial
for
controlling
infectious
diseases,
safeguarding
public
health,
and
ensuring
food
water
safety.
The
integration
of
metal-organic
frameworks
(MOFs)
with
aptamers
offers
a
promising
approach
to
enhance
bacterial
detection.
Aptamers
provide
high
specificity
target
recognition,
while
MOFs
contribute
tunable
porous
structures
stability,
forming
robust
biosensors.
This
synergy
improves
sensitivity,
selectivity,
versatility,
enabling
real-time
quantitative
Applications
span
safety,
environmental
monitoring,
point-of-care
diagnostics.
review
highlights
the
significance
aptamer@MOF
biosensors,
discussing
various
detection
techniques
aptamer
immobilization
methods.
It
also
addresses
challenges
like
enhancing
improving
minimizing
interference,
advancing
scalability
real-world
applications.
Additionally,
limitations
such
as
need
miniaturization,
multimode
detection,
multiplex
analysis
are
highlighted.
Future
directions
focus
on
optimizing
design
expanding
applications
overcome
these
limitations.
versatility
potential
biosensors
underscore
their
promise
high-performance
platforms
in
diverse
fields.
Materials Horizons,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 1, 2025
Significant
advancements
have
been
made
in
biochemical
sensing,
particularly
the
design,
development,
and
utilization
of
metallic
nanoclusters
metal–organic
frameworks
as
separate
functional
materials.
