A strong, antimildew, and fully bio-based adhesive fabricated by soybean meal and dialdehyde chitosan

Industrial Crops and Products, Journal Year: 2023, Volume and Issue: 194, P. 116277 - 116277

Published: Jan. 18, 2023

Language: Английский

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Bridging Smart Nanosystems with Clinically Relevant Models and Advanced Imaging for Precision Drug Delivery

Advanced Science, Journal Year: 2024, Volume and Issue: 11(14)

Published: Jan. 28, 2024

Abstract Intracellular delivery of nano‐drug‐carriers (NDC) to specific cells, diseased regions, or solid tumors has entered the era precision medicine that requires systematic knowledge nano‐biological interactions from multidisciplinary perspectives. To this end, review first provides an overview membrane‐disruption methods such as electroporation, sonoporation, photoporation, microfluidic delivery, and microinjection with merits high‐throughput enhanced efficiency for in vitro NDC delivery. The impact characteristics including particle size, shape, charge, hydrophobicity, elasticity on cellular uptake are elaborated several types systems aiming hierarchical targeting vivo reviewed. Emerging ex human/animal‐derived pathophysiological models further explored highly recommended use studies since they might mimic features fill translational gaps animals humans. exploration modern microscopy techniques precise nanoparticle (NP) tracking at cellular, organ, organismal levels informs tailored development NDCs application clinical translation. Overall, integrates latest insights into smart nanosystem engineering, physiological models, imaging‐based validation tools, all directed towards enhancing efficient intracellular NDCs.

Language: Английский

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Perforin‐Mimicking Molecular Drillings Enable Macroporous Hollow Lignin Spheres for Performance‐Configurable Materials

Advanced Materials, Journal Year: 2024, Volume and Issue: 36(15)

Published: Jan. 11, 2024

Abstract Despite the first observations that perforin can punch holes in target cells for live/dead cycles human immune system over 110 years ago, emulating this behavior materials science remains challenging. Here, a perforin‐mimicking molecular drilling strategy is employed to engineer macroporous hollow lignin spheres as performance‐configurable catalysts, adhesives, and gels. Using toolbox of 20 compounds, local curvature amphiphilic modulated generate with hole sizes ranging from 0 100 nm. Multiscale control precisely achieved through noncovalent assembly directing catalysis, synthesis, polymerization. Exceptional performance mutations correlate changes size, including an increase catalytic efficiency 50% 100%, transition nonstick synthetics ultrastrong adhesives (adhesion ≈18.3 MPa, exceeding classic epoxies), transformation viscous sols tough nanogels. Thus, study provides robust versatile route mimicking perforin‐induced structural variations cells, representing significant stride toward exquisite orchestration assemblies multiple length scales.

Language: Английский

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Aminated alkali lignin nanoparticles enabled formaldehyde-free biomass wood adhesive with high strength, toughness, and mildew resistance

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 494, P. 152914 - 152914

Published: June 7, 2024

Language: Английский

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Preparation, characterization, and application of waterborne lignin-based epoxy resin as eco-friendly wood adhesive

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 259, P. 129327 - 129327

Published: Jan. 12, 2024

Language: Английский

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