Microchemical Journal, Journal Year: 2025, Volume and Issue: unknown, P. 113986 - 113986
Published: May 1, 2025
Language: Английский
Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 496, P. 153914 - 153914
Published: July 13, 2024
Language: Английский
Citations
6
ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: 16(10), P. 12263 - 12276
Published: Feb. 29, 2024
Foodborne carbon dots (CDs) are generally produced during cooking and exist in food items. Generally, CDs regarded as nontoxic materials, but several studies have gradually confirmed the cytotoxicity of CDs, such oxidative stress, reduced cellular activity, apoptosis, etc. However, focusing on health effects long-term intake food-borne scarce, especially populations susceptible to metabolic disease. In this study, we reported that self-brewing beer had no effect glucose metabolism CHOW-fed mice exacerbated high-fat-diet (HFD)-induced disorders via gut-liver axis. Chronic exposure foodborne increased fasting levels liver intestinal barrier damage HFD-fed mice. The 16s rRNA sequencing analysis revealed significantly altered gut microbiota composition promoted lipopolysaccharide (LPS) synthesis-related KEGG pathways (superpathway (Kdo)2-lipid A, Kdo transfer lipid IVA Ill (Chlamydia), biosynthesis, so on) Mechanically, CD abundance Gram-negative bacteria (Proteobacteria Desulfovibrionaceae), thus producing excessive endotoxin-LPS, then LPS was transferred by blood circulation due damaged barrier. liver, TLR4/NF-κB/P38 MAPK signaling, enhancing systemic inflammation exacerbating HFD-induced insulin resistance. pretreating with antibiotics eliminated these effects, indicating a key role for finding herein provides new insight into potential risk nanoparticles disturbing
Language: Английский
Citations
4
Journal of Advanced Research, Journal Year: 2024, Volume and Issue: unknown
Published: April 1, 2024
Zearalenone (ZEN) is one of the most widely contaminated mycotoxins in world, posing a severe threat to human and animal health. Atmospheric cold plasma (ACP) holds great penitential mycotoxin degradation. This study aimed investigate degradation efficiency mechanisms ACP on ZEN as well cytotoxicity products by ACP. Additionally, this also investigated cereals its effect cereal quality. The was analyzed HPLC LC-MS/MS. normal liver cells mice were employed assess products. artificially used evaluate feasibility detoxification cereals. results showed that rate 96.18 % after 30-W treatment for 180 s. dependent discharge power, time distance. Four major produced due oxidative destruction CC double bond, namely C18H22O7 (m/z = 351.19), C18H22O8 367.14), C18H22O6 335.14), C17H20O6 321.19). L02 cell viability increased from 52.4 99.76 with ranging 0 Mice significant recovery body weight depth colonic crypts mitigation glomerular damage. removed up 50.55 58.07 wheat corn. demonstrates could efficiently degrade significantly reduced. Therefore, promising effective method ensure Future needs develop large-scale device high efficiency.
Language: Английский
Citations
4
Autoimmunity Reviews, Journal Year: 2024, Volume and Issue: 24(2), P. 103717 - 103717
Published: Dec. 9, 2024
Language: Английский
Citations
4
Nutrients, Journal Year: 2024, Volume and Issue: 16(14), P. 2302 - 2302
Published: July 17, 2024
Inflammatory bowel disease (IBD), a complex chronic inflammatory disorder that includes Crohn’s (CD) and Ulcerative Colitis (UC), has become globally increasing health concern. Nutrition, as an important factor influencing the occurrence development of IBD, attracted more attention. As most nutrient, protein can not only provide energy nutrition required by patients, but also help repair damaged intestinal tissue, enhance immunity, thus alleviate inflammation. Numerous studies have shown nutritional support plays significant role in treatment remission IBD. This article presents comprehensive review pathogenesis IBD analyzes summarizes potential mechanisms Additionally, it provides overview clinical effects its impact on complications. Research findings reveal demonstrates benefits improving symptoms, reducing risk complications, quality life patients. Therefore, is expected to new approach for
Language: Английский
Citations
4
Probiotics and Antimicrobial Proteins, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 3, 2025
Microplastics (MPs) and Di-(2-ethylhexyl) phthalate (DEHP) as emerging contaminants, have caused increasing concern due to their co-exposure risks toxicities humans. Lactic acid bacteria been demonstrated play a significant role in the mitigation of organismal damage. Probiotic intervention is widely recognized safe healthy therapeutic strategy for targeting organic This study explored effectiveness underlining mechanism an excellent probiotic property Lactiplantibacillus plantarum P101 (L. P101) combined hepatotoxicity MPs DEHP. In this study, mice were exposed DEHP via free drinking water, followed by with L. P101. Results showed that severe oxidative stress inflammation liver intestines, which was reversed after intervention. Moreover, reshaped structure gut microbiota alleviated damage exposure. Together, we found effectively mitigated toxic effects on system DEHP, offering promising reducing toxicity these substances.
Language: Английский
Citations
0
Environmental Research, Journal Year: 2025, Volume and Issue: unknown, P. 121119 - 121119
Published: Feb. 1, 2025
Language: Английский
Citations
0
Industrial Crops and Products, Journal Year: 2025, Volume and Issue: 226, P. 120707 - 120707
Published: Feb. 18, 2025
Language: Английский
Citations
0
Journal of Advanced Research, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 1, 2025
Language: Английский
Citations
0
Phytomedicine, Journal Year: 2025, Volume and Issue: 139, P. 156528 - 156528
Published: Feb. 22, 2025
Language: Английский
Citations
0