Sweat‐Permeable, Microbiota‐Preserving, Mechanically Antibacterial Patch for Long‐Term Interfacing with Perspiring Skin DOI Open Access

Yujiao Wu,

Xinyu Li,

Peiying He

et al.

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 23, 2024

Abstract The prolonged health monitoring using wearable technology faces challenges stemming from perspiration, including bacterial proliferation, compromised adhesion, signal quality deterioration, and user discomfort. Notably, excessive sweat fosters colonization, escalating infection risks, compromising biomarker analysis. Existing antibacterial approaches, unfortunately, risk disrupting the delicate balance of skin microbiota. To address this, a Janus patch featuring Zn‐Al layered double hydroxide (LDH) modification is developed, which exhibits sustained properties while preserving epidermal microecology. It integrates hydrophilic LDH fabric that mechanically eradicates bacteria via nanoknife effect, laser‐engraved medical adhesive with microholes for unidirectional transport. This innovative design not only enhances adhesion stability but also safeguards microbiome by preventing direct contact LDH. Moreover, seamlessly interfaces sweat‐monitoring technologies like microfluidic paper‐based analytical devices (uPADs) sensors, ensuring 100% efficacy efficient redirection reliable detection prioritizing comfort. can serve as durable bridge between perspiring revolutionizing realm long‐term monitoring.

Language: Английский

High‐Conductivity, Self‐Healing, and Adhesive Ionic Hydrogels for Health Monitoring and Human‐Machine Interactions Under Extreme Cold Conditions DOI Creative Commons
Fei Han, Shumeng Chen, Fei Wang

et al.

Advanced Science, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 28, 2025

Abstract Ionic conductive hydrogels (ICHs) are emerging as key materials for advanced human‐machine interactions and health monitoring systems due to their unique combination of flexibility, biocompatibility, electrical conductivity. However, a major challenge remains in developing ICHs that simultaneously exhibit high ionic conductivity, self‐healing, strong adhesion, particularly under extreme low‐temperature conditions. In this study, novel ICH composed sulfobetaine methacrylate, methacrylic acid, TEMPO‐oxidized cellulose nanofibers, sodium alginate, lithium chloride is presented. The hydrogel designed with hydrogen‐bonded chemically crosslinked network, achieving excellent conductivity (0.49 ± 0.05 S m −1 ), adhesion (36.73 2.28 kPa), self‐healing capacity even at −80 °C. Furthermore, the maintain functionality over 45 days, showcasing outstanding anti‐freezing properties. This material demonstrates significant potential non‐invasive, continuous monitoring, adhering conformally skin without signal crosstalk, enabling real‐time, high‐fidelity transmission cryogenic These offer transformative next generation multimodal sensors, broadening application possibilities harsh environments, including weather outer space.

Language: Английский

Citations

6
Skin-Interfaced Wearable Sensor for Long-Term Reliable Monitoring of Uric Acid and pH in Sweat DOI
Danfeng Jiang, Xiaohu Liu, Wenlong Zhan

et al.

Nano Letters, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 17, 2025

Wearable sweat sensors offering real-time monitoring of biomarker levels suffer from stability and accuracy issues, primarily due to low concentrations, fluctuating pH, material detachment sensor deformation. Here, we developed a wearable sensing system integrated with two advanced electrodes flexible microchannel for long-term reliable pH uric acid (UA). By printing the ink doped nanomaterials (Co3O4@CuCo2O4 polyaniline), achieved highly stable direct analysis perspiration, without additional surface modification. Additionally, provided means sensitivity calibration, reducing effect individual metabolism exercise intensity. As result, effective gout management was validated by accurately tracking UA fluctuations in serum hyperuricemia patients healthy individuals. These findings offer method biomarkers assess personal health.

Language: Английский

Citations

1
Photonic Nanomaterials for Wearable Health Solutions DOI Creative Commons
Taewoong Park, Jung Woo Leem, Young L. Kim

et al.

Advanced Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 3, 2025

Abstract This review underscores the transformative potential of photonic nanomaterials in wearable health technologies, driven by increasing demands for personalized monitoring. Their unique optical and physical properties enable rapid, precise, sensitive real‐time monitoring, outperforming conventional electrical‐based sensors. Integrated into ultra‐thin, flexible, stretchable formats, these materials enhance compatibility with human body, enabling prolonged wear, improved efficiency, reduced power consumption. A comprehensive exploration is provided integration devices, addressing material selection, light‐matter interaction principles, device assembly strategies. The highlights critical elements such as form factors, sensing modalities, data communication, representative examples skin patches contact lenses. These devices precise monitoring management biomarkers diseases or biological responses. Furthermore, advancements approaches have paved way continuum care systems combining multifunctional sensors therapeutic drug delivery mechanisms. To overcome existing barriers, this outlines strategies design, engineering, system integration, machine learning to inspire innovation accelerate adoption next‐generation health, showcasing their versatility digital applications.

Language: Английский

Citations

1
Flexible Electrochemical Capacitors based on ZnO-Carbon Black Composite DOI Creative Commons

Wajeeha Habib,

Anju Saji,

Febin Paul

et al.

Results in Engineering, Journal Year: 2025, Volume and Issue: unknown, P. 104510 - 104510

Published: Feb. 1, 2025

Language: Английский

Citations

1
Development and application of novel biosensors for enhanced detection in medical diagnostics DOI
A.M. Elbasiony, Sarah Alharthi, Mohamed Mohamady Ghobashy

et al.

Microchemical Journal, Journal Year: 2024, Volume and Issue: unknown, P. 111938 - 111938

Published: Oct. 1, 2024

Language: Английский

Citations

4
Recent Advances in Wearable Sweat Sensor Development DOI
Tao Zhang,

Giraso Keza Monia Kabandana,

John A. Terrell

et al.

Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology, Journal Year: 2025, Volume and Issue: 17(1)

Published: Jan. 1, 2025

Wearable sweat sensors for detecting biochemical markers have emerged as a transformative research area, with the potential to revolutionize disease diagnosis and human health monitoring. Since 2016, substantial body of pioneering translational work on has been reported. This review aims provide comprehensive summary current state-of-the-art in field, offering insights perspectives future developments. The focus is wearable microfluidic platforms collection delivery analytical chemistry applicable devices. Various technologies, including those based synthetic polymers, paper, textiles, hydrogels, are discussed alongside diverse detection methods such electrochemistry colorimetry. Both advantages limitations these technologies critically examined. concludes our sensors, goal inspiring new ideas, innovations, technical advancements further development practical application devices promoting health.

Language: Английский

Citations

0
Trends and Advances in Wearable Plasmonic Sensors Utilizing Surface-Enhanced Raman Spectroscopy (SERS): A Comprehensive Review DOI Creative Commons
Svetlana N. Khonina, Nikolay L. Kazanskiy

Sensors, Journal Year: 2025, Volume and Issue: 25(5), P. 1367 - 1367

Published: Feb. 23, 2025

Wearable sensors have appeared as a promising solution for real-time, non-invasive monitoring in diverse fields, including healthcare, environmental sensing, and wearable electronics. Surface-enhanced Raman spectroscopy (SERS)-based leverage the unique properties of SERS, such plasmonic signal enhancement, high molecular specificity, potential single-molecule detection, to detect identify wide range analytes with ultra-high sensitivity selectivity. However, it is important note that utilize various sensing mechanisms, not all rely on SERS technology, their design depends specific application. This comprehensive review highlights recent trends advancements technologies, focusing design, fabrication, integration into practical devices. Key innovations material selection, use nanomaterials flexible substrates, significantly enhanced sensor performance wearability. Moreover, we discuss challenges miniaturization, power consumption, long-term stability, along solutions address these issues. Finally, outlook technologies presented, emphasizing need interdisciplinary research drive next generation smart wearables capable real-time health diagnostics, monitoring, beyond.

Language: Английский

Citations

0
Applications and prospects of biomaterials in diabetes management DOI Creative Commons
Wei‐jie Guan, Liang Zhang

Frontiers in Bioengineering and Biotechnology, Journal Year: 2025, Volume and Issue: 13

Published: March 7, 2025

Diabetes is a widespread metabolic disorder that presents considerable challenges in its management. Recent advancements biomaterial research have shed light on innovative approaches for the treatment of diabetes. This review examines role biomaterials diabetes diagnosis and treatment, as well their application managing diabetic wounds. By evaluating recent developments alongside future obstacles, highlights promising potential care, underscoring importance enhancing patient outcomes refining methodologies.

Language: Английский

Citations

0
Emerging Multifunctional Wearable Sensors: Integrating Multimodal Sweat Analysis and Advanced Material Technologies for Next-Generation Health Monitoring DOI
C Ma, Xudong Shang, Mimi Sun

et al.

ACS Sensors, Journal Year: 2025, Volume and Issue: unknown

Published: March 31, 2025

Sweat, a noninvasive and readily accessible biofluid, offers significant potential in health monitoring through its diverse biomarker profile, including electrolytes, metabolites, hormones, which reflect physiological states real time. Multimodal wearable sensors, integrating chemical, physical, thermal sensing capabilities, have emerged as transformative tools for capturing these biomarkers alongside additional signals. By combining advanced materials such hydrogels, MXenes, graphene with innovative structural designs, sensors enable simultaneous of (e.g., glucose, sodium, cortisol) parameters like movement temperature. This Review systematically explores the classification design multimodal emphasizing their ability to address challenges across applications metabolic management, stress detection, hydration assessment. Key innovations functional materials, conductive hydrogels biomimetic structures, are discussed signal integration, data processing, power management. Additionally, advancements self-powered systems energy harvesting technologies been highlighted critical enablers continuous, real-time monitoring. The concludes perspective on future directions, need scalable manufacturing techniques, artificial intelligence standardized frameworks enhance sensor functionality adoption. by seamlessly into daily life, hold promise transforming personalized healthcare, enabling proactive management wellness noninvasive, comprehensive,

Language: Английский

Citations

0
A Fully Integrated Wearable Biomimetic Microfluidic Wound Tracker for In Situ Dynamic Monitoring of Wound Exudate Oxygen DOI

Wei Qiao Deng,

Mingzhi Sun,

Mengzhu Cao

et al.

ACS Nano, Journal Year: 2025, Volume and Issue: unknown

Published: April 16, 2025

Wearable wound exudate sensors hold great promise for providing dynamic measurements of valuable biomarkers. However, no existing are able to achieve the fully integrated, skin-on, and detection raw oxygen (O2), which is closely related conditions also essential healing. Here, we report a integrated wearable biomimetic microfluidic tracker, capable skin-on sampling, monitoring O2 in addition uric acid, lactate, pH, temperature, wireless control through seamless integration specially designed microfluidic, sensing, electronic modules. We test performance device both bacterium-inoculated uninoculated wounds using mouse models. further assess its potential management healing process infected diabetic controlled experiments local hyperbaric treatment.

Language: Английский

Citations

0