Environmental and Health Impacts of Graphene and Other Two-Dimensional Materials: A Graphene Flagship Perspective DOI Creative Commons

Hazel Lin,

Tina Buerki‐Thurnherr, Jasreen Kaur

et al.

ACS Nano, Journal Year: 2024, Volume and Issue: 18(8), P. 6038 - 6094

Published: Feb. 13, 2024

Two-dimensional (2D) materials have attracted tremendous interest ever since the isolation of atomically thin sheets graphene in 2004 due to specific and versatile properties these materials. However, increasing production use 2D necessitate a thorough evaluation potential impact on human health environment. Furthermore, harmonized test protocols are needed with which assess safety The Graphene Flagship project (2013-2023), funded by European Commission, addressed identification possible hazard graphene-based as well emerging including transition metal dichalcogenides, hexagonal boron nitride, others. Additionally, so-called green chemistry approaches were explored achieve goal safe sustainable this fascinating family nanomaterials. present review provides compact survey findings lessons learned Flagship.

Language: Английский

Nanomaterials for cancer therapy: current progress and perspectives DOI Creative Commons
Zhe Cheng, Maoyu Li,

Raja Dey

et al.

Journal of Hematology & Oncology, Journal Year: 2021, Volume and Issue: 14(1)

Published: May 31, 2021

Abstract Cancer is a disease with complex pathological process. Current chemotherapy faces problems such as lack of specificity, cytotoxicity, induction multi-drug resistance and stem-like cells growth. Nanomaterials are materials in the nanorange 1–100 nm which possess unique optical, magnetic, electrical properties. used cancer therapy can be classified into several main categories. Targeting cells, tumor microenvironment, immune system, these nanomaterials have been modified for wide range therapies to overcome toxicity enhance drug capacity well bioavailability. Although number studies has increasing, approved nano-drugs not increased much over years. To better improve clinical translation, further research needed targeted delivery by nano-carriers reduce toxicity, permeability retention effects, minimize shielding effect protein corona. This review summarizes novel fabricated use, discusses current limitations obstacles that hinder translation from provides suggestions more efficient adoption therapy.

Language: Английский

Citations

846

Toward Nanotechnology-Enabled Approaches against the COVID-19 Pandemic DOI Creative Commons
Carsten Weiß, Marie Carrière, Laura Fusco

et al.

ACS Nano, Journal Year: 2020, Volume and Issue: 14(6), P. 6383 - 6406

Published: June 10, 2020

The COVID-19 outbreak has fueled a global demand for effective diagnosis and treatment as well mitigation of the spread infection, all through large-scale approaches such specific alternative antiviral methods classical disinfection protocols. Based on an abundance engineered materials identifiable by their useful physicochemical properties versatile chemical functionalization, nanotechnology offers number to cope with this emergency. Here, multidisciplinary Perspective encompassing diverse fields virology, biology, medicine, engineering, chemistry, science, computational we outline how nanotechnology-based strategies can support fight against COVID-19, infectious diseases in general, including future pandemics. Considering what know so far about life cycle virus, envision key steps where could counter disease. First, nanoparticles (NPs) offer protocols used healthcare settings, thanks intrinsic antipathogenic and/or ability inactivate viruses, bacteria, fungi, or yeasts either photothermally via photocatalysis-induced reactive oxygen species (ROS) generation. Nanotechnology tools SARS-CoV-2 patients also be explored. In case, nanomaterials deliver drugs pulmonary system inhibit interaction between angiotensin-converting enzyme 2 (ACE2) receptors viral S protein. Moreover, concept "nanoimmunity design" help us design immune modulation, stimulating suppressing response, which would find applications context vaccine development counteracting cytokine storm, respectively. addition disease prevention therapeutic potential, important roles diagnostics, potential simple, fast, cost-effective assays monitor presence related biomarkers. summary, is critical will vital when preparing

Language: Английский

Citations

555

Graphene-Based Sensors for Human Health Monitoring DOI Creative Commons
Haizhou Huang, Shi Su, N. J. Wu

et al.

Frontiers in Chemistry, Journal Year: 2019, Volume and Issue: 7

Published: June 11, 2019

Since the desire for real-time human health monitoring as well seamless human-machine interaction is increasing rapidly, plenty of research efforts have been made to investigate wearable sensors and implantable devices in recent years. As a novel 2D material, graphene has aroused boom field sensor around world due its advantages mechanical, thermal, electrical properties. Numerous graphene-based used reported, including sensors, devices, which can realize measurement body temperature, heart rate, pulse oxygenation, respiration blood pressure, glucose, electrocardiogram signal, electromyogram electroencephalograph etc. Herein, review latest monitoring, their structures, sensing mechanisms, technological innovations, components systems potential challenges will be discussed outlined.

Language: Английский

Citations

279

Can graphene take part in the fight against COVID-19? DOI Open Access
Valentina Palmieri, Massimiliano Papi

Nano Today, Journal Year: 2020, Volume and Issue: 33, P. 100883 - 100883

Published: May 7, 2020

Language: Английский

Citations

241

Antiviral surfaces and coatings and their mechanisms of action DOI Creative Commons
Paulina D. Rakowska, Mariavitalia Tiddia,

Nilofar Faruqui

et al.

Communications Materials, Journal Year: 2021, Volume and Issue: 2(1)

Published: May 28, 2021

Abstract Viral infections are a serious health challenge, and the COVID-19 pandemic has increased demand for antiviral measures treatments clean surfaces, especially in public places. Here, we review range of natural synthetic surface materials coatings with properties, including metals, polymers biopolymers, graphene antimicrobial peptides, their underpinning mechanisms. We also discuss physico-chemical properties surfaces which influence virus attachment persistence on surfaces. Finally, an overview is given current practices applications virucidal consumer products, personal protective equipment, healthcare settings.

Language: Английский

Citations

203

Targeting cancer cells with nanotherapeutics and nanodiagnostics: Current status and future perspectives DOI
Eunüs S. Ali, Shazid Md. Sharker, Muhammad Torequl Islam

et al.

Seminars in Cancer Biology, Journal Year: 2020, Volume and Issue: 69, P. 52 - 68

Published: Jan. 31, 2020

Language: Английский

Citations

197

Biocompatibility and biodegradability of 2D materials: graphene and beyond DOI
Cristina Martín, Kostas Kostarelos, Maurizio Prato

et al.

Chemical Communications, Journal Year: 2019, Volume and Issue: 55(39), P. 5540 - 5546

Published: Jan. 1, 2019

The potential risks associated with two-dimensional (2D) nanomaterials may cause serious concerns about their real applications and impact in biological systems.

Language: Английский

Citations

187

Flexible graphene aerogel-based phase change film for solar-thermal energy conversion and storage in personal thermal management applications DOI

Keyan Sun,

Hongsheng Dong,

Yan Kou

et al.

Chemical Engineering Journal, Journal Year: 2021, Volume and Issue: 419, P. 129637 - 129637

Published: April 6, 2021

Language: Английский

Citations

169

Carbon-Based Nanomaterials: Promising Antiviral Agents to Combat COVID-19 in the Microbial-Resistant Era DOI Creative Commons
Ángel Serrano‐Aroca, Kazuo Takayama, Alberto Tuñón-Molina

et al.

ACS Nano, Journal Year: 2021, Volume and Issue: 15(5), P. 8069 - 8086

Published: April 7, 2021

Therapeutic options for the highly pathogenic human severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing current pandemic disease (COVID-19) are urgently needed. COVID-19 is associated with viral pneumonia and distress significant morbidity mortality. The proposed treatments have shown little or no effect in clinic so far. Additionally, bacterial fungal pathogens contribute to SARS-CoV-2-mediated complex. antibiotic resistance treatment increasing at an alarming rate. Therefore, carbon-based nanomaterials (CBNs), such as fullerene, carbon dots, graphene, their derivatives constitute a promising alternative due wide-spectrum antimicrobial activity, biocompatibility, biodegradability, capacity induce tissue regeneration. Furthermore, mode of action mainly physical (e.g., membrane distortion), characterized by low risk resistance. In this Review, we evaluated literature on antiviral activity broad-spectrum properties CBNs. CBNs had against 13 enveloped positive-sense single-stranded RNA viruses, including SARS-CoV-2. toxicity humans therapeutics complex other bacteria, fungi, those that multidrug-resistant.

Language: Английский

Citations

161

Graphene and CNT‐Based Smart Fiber‐Reinforced Composites: A Review DOI Creative Commons
Mohammad Hamidul Islam, Shaila Afroj, Mohammad Abbas Uddin

et al.

Advanced Functional Materials, Journal Year: 2022, Volume and Issue: 32(40)

Published: Aug. 23, 2022

Multifunctional fiber-reinforced polymer (FRP) composites provide an ideal platform for next-generation smart applications including structural health monitoring, electrical and thermal conductivity, energy storage harvesting, electromagnetic interference shielding without compromising their mechanical properties. Recent progress in carbon-based nanomaterials such as graphene carbon nanotubes (CNTs) has enabled the development of many novel multifunctional with excellent mechanical, electrical, However, effective incorporation into FRP using scalable, high-speed, cost-effective manufacturing performance is challenging. This review summarizes recent on CNT-based composites, techniques, composites. Current technical challenges future perspectives research to facilitate essential step toward moving from development-based industrial-scale mass production are also discussed.

Language: Английский

Citations

158