Flexible electrochemical sensors integrated with nanomaterials for in situ determination of small molecules in biological samples: A review DOI
Lin Tao, Yun Xu, Anshun Zhao

et al.

Analytica Chimica Acta, Journal Year: 2022, Volume and Issue: 1207, P. 339461 - 339461

Published: Jan. 15, 2022

Language: Английский

End-to-end design of wearable sensors DOI Open Access
H. Ceren Ates, Peter Q. Nguyen, Laura Gonzalez‐Macia

et al.

Nature Reviews Materials, Journal Year: 2022, Volume and Issue: 7(11), P. 887 - 907

Published: July 22, 2022

Language: Английский

Citations

723

A wearable electrochemical biosensor for the monitoring of metabolites and nutrients DOI Open Access
Minqiang Wang, Yiran Yang, Jihong Min

et al.

Nature Biomedical Engineering, Journal Year: 2022, Volume and Issue: 6(11), P. 1225 - 1235

Published: Aug. 15, 2022

Language: Английский

Citations

527

Artificial Intelligence (AI) and Internet of Medical Things (IoMT) Assisted Biomedical Systems for Intelligent Healthcare DOI Creative Commons
Pandiaraj Manickam, Siva Ananth Mariappan,

Sindhu Monica Murugesan

et al.

Biosensors, Journal Year: 2022, Volume and Issue: 12(8), P. 562 - 562

Published: July 25, 2022

Artificial intelligence (AI) is a modern approach based on computer science that develops programs and algorithms to make devices intelligent efficient for performing tasks usually require skilled human intelligence. AI involves various subsets, including machine learning (ML), deep (DL), conventional neural networks, fuzzy logic, speech recognition, with unique capabilities functionalities can improve the performances of medical sciences. Such systems simplify intervention in clinical diagnosis, imaging, decision-making ability. In same era, Internet Medical Things (IoMT) emerges as next-generation bio-analytical tool combines network-linked biomedical software application advancing health. this review, we discuss importance improving IoMT point-of-care (POC) used advanced healthcare sectors such cardiac measurement, cancer diabetes management. The role supporting robotic surgeries developed applications also discussed article. position functionality, detection accuracy, ability devices, evaluation associated risks assessment carefully critically review. This review encompasses technological engineering challenges prospects AI-based cloud-integrated personalized designing POC suitable healthcare.

Language: Английский

Citations

377

Skin-Interfaced Wearable Sweat Sensors for Precision Medicine DOI
Jihong Min, Jiaobing Tu, Changhao Xu

et al.

Chemical Reviews, Journal Year: 2023, Volume and Issue: 123(8), P. 5049 - 5138

Published: March 27, 2023

Wearable sensors hold great potential in empowering personalized health monitoring, predictive analytics, and timely intervention toward healthcare. Advances flexible electronics, materials science, electrochemistry have spurred the development of wearable sweat that enable continuous noninvasive screening analytes indicative status. Existing major challenges include: improving extraction sensing capabilities, form factor device for minimal discomfort reliable measurements when worn, understanding clinical value biomarker discovery. This review provides a comprehensive outlines state-of-the-art technologies research strive to bridge these gaps. The physiology sweat, materials, biosensing mechanisms advances, approaches induction sampling are introduced. Additionally, design considerations system-level devices, spanning from strategies prolonged efficient powering wearables, discussed. Furthermore, applications, data commercialization efforts, challenges, prospects precision medicine

Language: Английский

Citations

345

The Emergence of AI-Based Wearable Sensors for Digital Health Technology: A Review DOI Creative Commons
Shaghayegh Shajari,

Kirankumar Kuruvinashetti,

Amin Komeili

et al.

Sensors, Journal Year: 2023, Volume and Issue: 23(23), P. 9498 - 9498

Published: Nov. 29, 2023

Disease diagnosis and monitoring using conventional healthcare services is typically expensive has limited accuracy. Wearable health technology based on flexible electronics gained tremendous attention in recent years for patient owing to attractive features, such as lower medical costs, quick access data, ability operate transmit data harsh environments, storage at room temperature, non-invasive implementation, mass scaling, etc. This provides an opportunity disease pre-diagnosis immediate therapy. sensors have opened a new area of personalized by accurately measuring physical states biochemical signals. Despite the progress date development wearable sensors, there are still several limitations accuracy collected, precise diagnosis, early treatment. necessitates advances applied materials structures artificial intelligence (AI)-enabled extract target signals accurate clinical decision-making efficient care. In this paper, we review two significant aspects smart sensors. First, offer overview most improving sensor performance physical, chemical, biosensors, focusing materials, structural configurations, transduction mechanisms. Next, use AI combination with big processing, self-learning, power-efficiency, real-time acquisition intelligent sensing platform. Finally, present challenges future opportunities associated

Language: Английский

Citations

136

Electrochemical sensors: From the bench to the skin DOI
Kuldeep Mahato, Joseph Wang

Sensors and Actuators B Chemical, Journal Year: 2021, Volume and Issue: 344, P. 130178 - 130178

Published: May 28, 2021

Language: Английский

Citations

127

Metal-organic frameworks (MOFs) based luminescent and electrochemical sensors for food contaminant detection DOI
Brij Mohan,

Priyanka Priyanka,

Gurjaspreet Singh

et al.

Journal of Hazardous Materials, Journal Year: 2023, Volume and Issue: 453, P. 131324 - 131324

Published: April 1, 2023

Language: Английский

Citations

113

Biomolecular sensors for advanced physiological monitoring DOI Creative Commons
Connor D. Flynn, Dingran Chang,

Alam Mahmud

et al.

Nature Reviews Bioengineering, Journal Year: 2023, Volume and Issue: 1(8), P. 560 - 575

Published: May 11, 2023

Body-based biomolecular sensing systems, including wearable, implantable and consumable sensors allow comprehensive health-related monitoring. Glucose have long dominated wearable bioanalysis applications owing to their robust continuous detection of glucose, which has not yet been achieved for other biomarkers. However, access diverse biological fluids the development reagentless approaches may enable design body-based systems various analytes. Importantly, enhancing selectivity sensitivity is essential biomarker in complex physiological conditions. In this Review, we discuss signal amplification sensors, techniques overcome Debye mass transport limitations, improvement, such as integration artificial affinity recognition elements. We highlight that can sequential real-time measurements, example, implementation thin-film transistors devices. addition sensor construction, careful consideration physical, psychological security concerns related required ensure transition from laboratory human body seamless possible. Continuous monitoring signatures potential transform our understanding personalized preventative medicine. This Review Article discusses emerging trends pertinent considerations a new generation vivo measurement.

Language: Английский

Citations

102

Natural oxidase-mimicking copper-organic frameworks for targeted identification of ascorbate in sensitive sweat sensing DOI Creative Commons
Zhengyun Wang, Yuchen Huang,

Kunqi Xu

et al.

Nature Communications, Journal Year: 2023, Volume and Issue: 14(1)

Published: Jan. 5, 2023

Abstract Sweat sensors play a significant role in personalized healthcare by dynamically monitoring biochemical markers to detect individual physiological status. The specific response the target biomolecules usually depends on natural oxidase, but it is susceptible external interference. In this work, we report tryptophan- and histidine-treated copper metal-organic frameworks (Cu-MOFs). This amino-functionalized copper-organic framework shows highly selective activity for ascorbate oxidation can serve as an efficient oxidase-mimicking material sensitive sweat sensors. Experiments calculation results elucidate that introduced tryptophan/histidine fundamentally regulates adsorption behaviors of biomolecules, enabling be selectively captured from complex further efficiently electrooxidized. work provides not only paradigm specifically sensing also understanding oxidase-inspired MOF nanoenzymes technologies beyond.

Language: Английский

Citations

86

The Future of Food DOI Creative Commons
Charis M. Galanakis

Foods, Journal Year: 2024, Volume and Issue: 13(4), P. 506 - 506

Published: Feb. 6, 2024

The global food systems face significant challenges driven by population growth, climate change, geopolitical conflicts, crises, and evolving consumer preferences. Intending to address these challenges, optimizing production, adopting sustainable practices, developing technological advancements are essential while ensuring the safety public acceptance of innovations. This review explores complex aspects future food, encompassing security, climate-resilient digitalized supply chain, alternative protein sources, processing, technology, impact biotechnology, cultural diversity culinary trends, health personalized nutrition, production within circular bioeconomy. article offers a holistic perspective on industry characterized innovation, adaptability, shared commitment system resilience. Achieving sustainable, nutritious, environmentally friendly in involves comprehensive changes various including innovative farming processing technologies, Industry 4.0 applications, as well approaches that redefine how we consume food.

Language: Английский

Citations

84