ACS Sensors,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 4, 2025
Recently,
flexible
electronics
have
significantly
transformed
information
and
communications
technology
(ICT).
In
particular,
wearable
devices,
via
integration
with
attachable
biosensors,
driven
the
development
of
new
types
biosensors
diagnostic
devices
for
point-of-care
testing
(POCT).
Moreover,
electrochemical
can
be
applied
to
diagnose
diseases
in
real
time
based
on
synergistic
effect
generated
from
incorporation
technique.
Besides,
improve
sensitivity
while
retaining
their
wearability,
novel
nanomaterials
nanotechnologies
been
introduced.
this
review,
recent
studies
nanotechnology-based
accurate
disease
diagnosis
are
discussed.
First,
widely
used
techniques
developing
electrodes,
including
nanolithography-
nano/microneedle-based
patches,
presented.
Next,
latest
such
as
diabetes
dermatitis
discussed
by
categorizing
into
categories.
Finally,
review
explores
research
trends
application
nanotechnology-enabled
nanopatterning
nano/microneedle
technologies
biosensors.
This
suggests
approaches
methods
real-time
under
POCT
applications.
Advanced Science,
Journal Year:
2024,
Volume and Issue:
11(12)
Published: Jan. 15, 2024
Abstract
Point‐of‐care
(POC)
has
the
capacity
to
support
low‐cost,
accurate
and
real‐time
actionable
diagnostic
data.
Microneedle
sensors
have
received
considerable
attention
as
an
emerging
technique
evolve
blood‐based
diagnostics
owing
their
direct
painless
access
a
rich
source
of
biomarkers
from
interstitial
fluid.
This
review
systematically
summarizes
recent
innovations
in
microneedle
with
particular
focus
on
utility
POC
personalized
medicine.
The
integration
various
sensing
techniques,
mostly
electrochemical
optical
sensing,
been
established
diverse
architectures
“lab‐on‐a‐microneedle”
platforms.
tailored
geometries,
mechanical
flexibility,
biocompatibility
are
constructed
variety
materials
fabrication
methods.
Microneedles
categorized
into
four
types:
metals,
inorganics,
polymers,
hydrogels,
elaborated
state‐of‐the‐art
bioengineering
strategies
for
minimally
invasive,
continuous,
multiplexed
sensing.
employed
detect
wide
range
electrolytes,
metabolites,
polysaccharides,
nucleic
acids,
proteins
drugs.
Insightful
perspectives
outlined
biofluid,
microneedles,
biosensors,
devices,
theragnostic
instruments,
which
depict
bright
future
upcoming
intelligent
health
management.
Communications Materials,
Journal Year:
2024,
Volume and Issue:
5(1)
Published: March 13, 2024
Abstract
Interstitial
fluid
(ISF),
a
biological
rich
in
diverse
biomarkers
and
analytes
similar
to
blood
composition,
has
garnered
significant
attention
as
valuable
source
of
clinically
relevant
information.
Consequently,
ISF-based
wearable
biosensors
are
emerging
powerful
tools
for
non-invasive
minimally
invasive
disease
diagnosis,
personalized
medicine,
other
healthcare
biomedical
applications.
This
review
provides
comprehensive
overview
recent
advancements
biosensors,
with
particular
focus
on
ISF
sensors.
We
first
offer
insights
into
sampling
techniques
discuss
sensing
strategies
that
encompass
materials,
fabrication
methods,
mechanisms.
Then,
we
present
their
Finally,
address
the
challenges
faced
this
field
forward-looking
perspective
promising
future
directions.
ACS Sensors,
Journal Year:
2024,
Volume and Issue:
9(3), P. 1065 - 1088
Published: March 1, 2024
Managing
diabetes
is
a
chronic
challenge
today,
requiring
monitoring
and
timely
insulin
injections
to
maintain
stable
blood
glucose
levels.
Traditional
clinical
testing
relies
on
fingertip
or
venous
collection,
which
has
facilitated
the
emergence
of
continuous
(CGM)
technology
address
data
limitations.
Continuous
recognized
for
tracking
long-term
fluctuations,
its
development,
particularly
in
wearable
devices,
given
rise
compact
portable
facilitates
measurement
adjustment
medication.
This
review
introduces
development
CGM-based
technologies,
including
noninvasive
methods
using
body
fluids
invasive
implantable
electrodes.
The
advantages
disadvantages
these
approaches
are
discussed
as
well
use
microneedle
arrays
minimally
CGM.
Microneedle
allow
painless
transdermal
puncture
expected
facilitate
CGM
devices.
Finally,
we
discuss
challenges
opportunities
look
forward
biomedical
applications
future
directions
technologies
biological
research.
Advanced Functional Materials,
Journal Year:
2024,
Volume and Issue:
34(26)
Published: Feb. 29, 2024
Abstract
Chronic,
non‐healing
wounds
pose
significant
challenges
for
public
health,
particularly
in
the
context
of
diabetes,
and
carry
economic
consequences.
This
article
introduces
a
new
solution
form
wireless
theranostic
patch,
developed
to
meet
critical
need
real‐time
monitoring
targeted
treatments
facilitate
optimal
healing.
The
patch
incorporates
advanced
materials
that
are
both
multifunctional
electro‐responsive,
leveraging
sophisticated
blend
smart
hydrogels
wearable
bioelectronics
support
diabetic
wound
management
with
unparalleled
efficacy.
With
electro‐responsive
polymer
at
its
core,
delivers
stretchable,
antimicrobial,
moist
environment
wound,
added
benefits
such
as
conductivity
visibility.
also
allow
continuous
autonomous
glucose
pH
levels,
providing
precise
personalized
like
insulin
delivery
via
iontophoresis
electrical
stimulation.
Animal
models
have
demonstrated
this
integrated
system
is
highly
adaptable,
effectively
promoting
closure
Overall,
offers
an
exciting
prospect
healthcare
solutions,
adopting
patient‐centric
approach
prioritizes
real‐time,
care
chronic
wounds.
Its
incorporation
electro‐controlled
paves
way
innovative
approaches
management.
Soft Science,
Journal Year:
2024,
Volume and Issue:
4(2)
Published: April 22, 2024
This
comprehensive
review
underscores
the
pivotal
role
wearable
electrochemical
sensors
play
in
proactive
management
and
prevention
of
diabetes
mellitus
(DM)
its
associated
complications.
Acknowledging
substantial
impact
DM
on
individuals
urgency
for
effective
monitoring
strategies,
have
emerged
as
a
pragmatic
solution.
These
can
detect
analytical
signals
from
biofluids,
including
sweat,
tears,
saliva,
interstitial
fluid
(ISF),
employing
minimally
invasive
techniques
facilitated
by
technological
advancements.
The
seamless
integration
these
with
computational
platforms
such
smartphones
enhances
their
practicality
routine
use.
systematically
explores
diverse
methodologies,
encompassing
both
enzymatic
non-enzymatic
principles,
employed
surveillance
analytes
within
biofluids.
foundational
principles
are
meticulously
applied
to
devices,
affording
point-of-care
solutions
catering
detection
individual
or
simultaneous
multiplexed
analyte
detection.
wireless
systems
incorporation
machine
learning
algorithms
introduce
layer
sophistication,
elevating
capability
nuanced
Through
an
in-depth
analysis
advancements,
this
describes
significant
potential
essential
tool
real-time
managing
DM.
approaches
presented
underscore
adaptability,
versatility,
inherent
efficacy
addressing
multifaceted
challenges
intrinsic
complications
academic
discourse.
Journal of Materials Chemistry B,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 1, 2025
With
the
miniaturization,
integration
and
intelligence
of
sweat
electrochemical
sensor
technology,
hydrogel
flexible
sensors
have
demonstrated
immense
potential
in
field
real-time
non-invasive
personal
health
monitoring.
