ACS Applied Bio Materials,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 8, 2024
Ru(bpy)32+
is
commonly
used
in
electrochemiluminescence
(ECL)
as
a
conventional
luminophore.
However,
can
leak
off
the
electrode
surface,
resulting
reduced
ECL
signal.
In
this
work,
nanocube
composite
material
Ru@ZIF
was
prepared
by
incorporating
doping
luminescent
into
skeleton
of
Zn(II)
ions
and
2-methylimidazole
(2-MI),
probe
Ru@ZIF-Pd
situ
growth
Pd
nanoparticles
(Pd
NPs).
Potassium
persulfate
(K2S2O8)
coreactant
to
investigate
cathodic
behavior.
The
ZnCoCH@MXene-Au
(ZC@T-Au)
accelerator
promote
production
SO4•–,
which
effectively
amplified
intensity
Ru@ZIF-Pd.
Under
optimal
experimental
conditions,
we
successfully
constructed
an
aptamer
sensor,
achieves
accurate
detection
acetamiprid
from
0.1
fM
10
μM
with
limit
0.029
fM.
It
provides
potential
idea
for
pesticide
residues
food.
Analytical Chemistry,
Journal Year:
2024,
Volume and Issue:
96(31), P. 12838 - 12845
Published: July 25, 2024
MicroRNA
(miRNA)
detection
is
a
critical
aspect
of
disease
diagnosis,
and
recent
studies
indicate
that
miRNA-622
could
be
potential
target
for
lung
cancer.
Herein,
Cu
single
atoms
were
anchored
on
graphitic
carbon
nitride
(Cu
SAs@CN)
as
coreaction
accelerator
applied
in
luminol-H
Small,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 18, 2024
Abstract
Exploring
novel
electrochemiluminescence
(ECL)
co‐reaction
accelerators
to
construct
ultrasensitive
sensing
systems
is
a
prominent
focus
for
developing
advanced
ECL
sensors.
However,
challenges
still
remain
in
finding
highly
efficient
and
understanding
their
promoting
mechanisms.
In
this
paper,
ZIF‐67@MXene
nanosheet
composites,
with
conductive
in‐plane
structure
confined‐stable
pore/channel,
are
designed
act
as
high‐efficient
achieve
significant
enhancement
the
luminol‐H
2
O
based
system.
Mechanism
investigation
suggests
that
hydroxyl
radicals
(·OH)
singlet
oxygen
(
1
)
can
be
selectively
preferentially
generated
on
due
stable
absorption
of
·OH
,
leading
remarkable
efficiency
luminol
(830%).
Finally,
by
designing
plasmonic
NH
‐MIL‐88@Pd
nanozyme,
an
“on‐off”
switch
immunosensor
constructed
detection
prostate‐specific
antigen
(PSA).
Based
multiple
signal
amplification
effect,
linear
range
PSA
expanded
three
orders
magnitude.
The
limit
also
improved
from
1.44
×
10
−11
9.1
−13
g
mL
−1
.
This
work
proposes
effective
method
preparation
provides
new
strategy
sensitive
cancer
markers.
ACS Sensors,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 19, 2025
With
the
goal
of
impacting
patient
quality
life
and
outcomes,
sensor
science
offers
significant
potential
to
revolutionize
healthcare
by
providing
advances
in
detection
molecular
biomarkers
for
personalized
clinical
technologies.
The
community
has
achieved
technical
advancements
that
can
impact
diagnostics,
health
monitoring,
disease
treatment;
however,
many
innovations
remain
confined
laboratory,
failing
bridge
translational
gap
between
research
real-world
applications.
This
perspective
presents
a
new
direction
community,
where
development
centers
on
needs
experiences
primary
beneficiaries:
patients.
We
provide
guidelines
resources
researchers
engage
with
patients
early
continuously
throughout
process
inform
specifications
better
align
technologies
needs,
improving
their
adoption
impact.
also
present
examples
implementing
patient-centered
approach
planning
engagement
research.
In
design
impactful
sensors
patients,
must
expand
focus
beyond
embrace
approach,
which
will
likely
lead
opportunities
collaboration
evolution
community.
