Quantification of Linker Defects in UiO-Type Metal–Organic Frameworks

Chemistry of Materials, Journal Year: 2023, Volume and Issue: 35(10), P. 3793 - 3800

Published: May 8, 2023

Metal–organic frameworks (MOFs) are nanoporous materials composed of organic linkers and inorganic nodes. The large variety nodes the multiple ways to combine them make MOFs highly tunable materials, which thoroughly studied for their use in, e.g., catalysis, gas capture, separation. chemistry is further enriched by defects, missing linker provide active sites catalysis or anchoring introducing new functionalities. A commonly reported method quantify defects assumes presence one type complete removal capping agents, solvents, other impurities upon activation at high temperature, 400 °C (M-400). However, attempts this containing different types linkers, also called multivariate (MTV-MOFs), agents that not completely removed °C, give inaccurate results hamper comparing from publications. In work, we have developed a procedure compute in Zr-based using standard analytical techniques remain MOF 200 (M-200). This method, has been tested UiO-66/67 based MOFs, should be applicable any (1) known decomposition products, (2) no cluster (3) empty pores contain species can quantified after activation, (4) node composition °C.

Language: Английский

---

Metal–organic framework-based smart stimuli-responsive drug delivery systems for cancer therapy: advances, challenges, and future perspectives

Journal of Nanobiotechnology, Journal Year: 2025, Volume and Issue: 23(1)

Published: Feb. 28, 2025

Cancer treatment is currently one of the most critical healthcare issues globally. A well-designed drug delivery system can precisely target tumor tissues, improve efficacy, and reduce damage to normal tissues. Stimuli-responsive systems (SRDDSs) have shown promising application prospects. Intelligent nano responsive endogenous stimuli such as weak acidity, complex redox characteristics, hypoxia, active energy metabolism, well exogenous like high temperature, light, pressure, magnetic fields are increasingly being applied in chemotherapy, radiotherapy, photothermal therapy, photodynamic various other anticancer approaches. Metal–organic frameworks (MOFs) become candidate materials for constructing SRDDSs due their large surface area, tunable porosity structure, ease synthesis modification, good biocompatibility. This paper reviews MOF-based modes cancer therapy. It summarizes key aspects, including classification, synthesis, modifications, loading modes, stimuli-responsive mechanisms, roles different modalities. Furthermore, we address current challenges summarize potential applications artificial intelligence MOF synthesis. Finally, propose strategies enhance efficacy safety SRDDSs, ultimately aiming at facilitating clinical translation.

Language: Английский

---

Strategies for induced defects in metal–organic frameworks for enhancing adsorption and catalytic performance

Dalton Transactions, Journal Year: 2022, Volume and Issue: 51(21), P. 8133 - 8159

Published: Jan. 1, 2022

Metal–organic frameworks (MOFs) have emerged among porous materials.

Language: Английский

---

The green chemistry paradigm in modern organic synthesis

Russian Chemical Reviews, Journal Year: 2023, Volume and Issue: 92(12), P. RCR5104 - RCR5104

Published: Dec. 1, 2023

After the appearance of green chemistry concept, which was introduced in vocabulary early 1990s, its main statements have been continuously developed and modified. Currently, there are 10–12 cornerstones that should form basis for an ideal chemical process. This review analyzes accumulated experience achievements towards design products processes reduce or eliminate use generation hazardous substances. The presents views leading Russian scientists specializing various fields this subject, including homogeneous heterogeneous catalysis, fine basic organic synthesis, electrochemistry, polymer chemistry, based on bio-renewable feedstocks energetic compounds materials. A new approach to quantitative evaluation environmental friendliness by authors is described. <br> bibliography includes 1761.

Language: Английский

---

Synthesis and modification methods of metal-organic frameworks and their application in modification of polymeric ultrafiltration membranes: A review

Journal of environmental chemical engineering, Journal Year: 2023, Volume and Issue: 11(3), P. 109954 - 109954

Published: April 18, 2023

Language: Английский

---

Cyclodextrin-metal-organic frameworks in molecular delivery, detection, separation, and capture: An updated critical review

Carbohydrate Polymers, Journal Year: 2023, Volume and Issue: 306, P. 120598 - 120598

Published: Jan. 18, 2023

Language: Английский

---

Efficient Electrochemical Lead Detection by a Histidine-Grafted Metal–Organic Framework MOF-808 Electrode Material

ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: 16(2), P. 2509 - 2521

Published: Jan. 3, 2024

As the excessive presence of heavy metals in environment significantly affects human health, it becomes necessary to develop efficient, selective, and sensitive methods for their detection. In this study, a novel electrochemical sensor detection Pb2+ ions is described. The proposed based on glassy carbon electrode (GCE) modified by thin film histidine-grafted metal–organic framework (MOF-808-His). MOF-808 was obtained solvothermally, then postsynthetically substituting coordinated acetate with histidinate. By electrochemistry, MOF-808-His-modified GCE demonstrated high charge selectivity, while impedance spectroscopy (EIS) kinetic studies gave lower transfer resistance (4196 Ω) better standard heterogeneous electron rate constant (1.80 × 10–5 cm s–1) MOF-808-modified GCE. These results indicated swift direct from [Fe(CN)6]3–/4– surface. Using square wave anodic stripping voltammetry (SWASV), rapid highly determination achieved optimizing accumulation-detection parameters including pH medium, deposition time potential, concentration, remarkable limit (LoD, signal-to-noise ratio 3) (1.12 10–10 ± 0.10 10–10) mol L–1 obtained, sensitivity (9.6 0.1) μA L μmol–1. After interference stability studies, applied tap water sample concentration 10 μmol Pb2+.

Language: Английский

---

Two-Dimensional Cu(II)-MOF with Lewis Acid–Base Bifunctional Sites for Chemical Fixation of CO₂ and Bioactive 1,4-DHP Synthesis via Hantzsch Condensation

Inorganic Chemistry, Journal Year: 2024, Volume and Issue: 63(23), P. 10832 - 10842

Published: May 29, 2024

Five- and six-membered heterocycles containing nitrogen or oxygen have been considered as privileged scaffolds in organic chemistry the chemical industry because of their usage high-value commodities. Herein, we report a two-dimensional (2D) Cu(II)-based MOF catalyst, IITKGP-40, via strategic employment ample Lewis acid–base bifunctional sites (open metal nodes free pyrazine moieties) along pore wall. IITKGP-40 could convert toxic CO2 to cyclic carbonates an atom-economical manner under solvent-free conditions aromatic aldehyde bioactive 1,4-DHPs Hantzsch condensation. Exceptional catalytic performance (99%) turnover number mild reaction for fixation using sterically hindered styrene oxide, good-to-excellent yields wide range aldehydes toward 1,4-dihydropyridines (1,4-DHPs) make promising multipurpose heterogeneous catalyst. Moreover, demonstrate practical utility two biologically important drug molecules, diludine nitrendipine analogue, also synthesized. is recyclable at least three consecutive runs without significant loss activity, making it real-time applications.

Language: Английский

---

Localized Surface Plasmon Resonance Increases Pulse Voltammetry Detection of Nitrite by Noble-Metal Modified Zirconium-Based Metal–Organic Frameworks: Fabrication and Mechanism

ACS Applied Electronic Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 22, 2025

Language: Английский

---

Bifunctional MOFs in Heterogeneous Catalysis

ACS Organic & Inorganic Au, Journal Year: 2023, Volume and Issue: 4(1), P. 59 - 90

Published: Nov. 11, 2023

The ever-increasing landscape of heterogeneous catalysis, pure and applied, utilizes many different catalysts. Academic insights along with industrial adaptations paved the way for growth. In designing a catalyst, it is desirable to have priori knowledge what structure needs be targeted help in achieving goal. When focusing on one cope vast corpus information. overwhelming desire exploit catalysis toward commercial ends irresistible. today's world, requirements developing new catalyst address environmental concerns. well-established catalysts microporous structures (<25 Å), which find use processes. metal–organic framework (MOF) compounds, being pursued vigorously during last two decades, similar microporosity well-defined pores channels. MOFs possess large surface area assemble delicate structural compositional variations either preparation or through postsynthetic modifications (PSMs). MOFs, fact, offer excellent scope as simple Lewis acidic, Brönsted basic, more importantly bifunctional (acidic well basic) agents carrying out catalysis. advances that happened over years biology helped design good biocatalysts. tools techniques (advanced preparative approaches coupled computational insights), other hand, generating interesting inorganic this review, recent employing are presented. doing so, we concentrated developments past decade so.

Language: Английский

---