Recent advances in the synthesis of azetidines DOI
Vahideh Zadsirjan,

Fatemeh Soleimani

Tetrahedron, Journal Year: 2024, Volume and Issue: 169, P. 134383 - 134383

Published: Nov. 19, 2024

Language: Английский

β-C−H bond functionalization of ketones and esters by cationic Pd complexes DOI
Yi-Hao Li, Nikita Chekshin, Yilin Lu

et al.

Nature, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 8, 2025

Language: Английский

Citations

6
Pd-catalyzed regioselective activation of C(sp2)–H and C(sp3)–H bonds DOI
Wajid Ali, Gwyndaf A. Oliver, Daniel B. Werz

et al.

Chemical Society Reviews, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Differentiating between two highly similar C-H bonds in a given molecule remains fundamental challenge synthetic organic chemistry. Directing group assisted strategies for the functionalisation of proximal has been known last few decades. However, distal bond is strenuous and requires distinctly specialised techniques. In this review, we summarise advancement Pd-catalysed C(sp

Language: Английский

Citations

11
Unified approaches in transition metal catalyzed C(sp3)–H functionalization: recent advances and mechanistic aspects DOI
Jagrit Grover,

Amal Tom Sebastian,

S.K. Maiti

et al.

Chemical Society Reviews, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Direct alteration of unactivated C–H bonds organic building blocks.

Language: Английский

Citations

1
Modular Synthesis of 1,2-Benzothiazines and 1,2-Benzothiazine 1-Imines via Palladium-Catalyzed C–H/C–C Activation Reactions DOI
Yifan Ren,

Lisha Mo,

Yali Wang

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(5), P. 3345 - 3358

Published: Feb. 19, 2024

In this study, a modular approach toward cyclic sulfoximines and sulfondiimines via palladium-catalyzed intramolecular C-H/C-C activation reactions was reported. Various 1,2-benzothiazines including bicyclic, tricyclic, highly fused ones, ones of the seven-membered ring, along with 1,2-benzothiazine 1-imines were accessed in good yields. KIE experiment demonstrated that C-H bond cleavage at position

Language: Английский

Citations

3
Site‐Selective Distal C(sp3)–H Bromination of Aliphatic Amines as a Gateway for Forging Nitrogen‐Containing sp3 Architectures DOI Creative Commons
Jinhong Chen, Clarence Tan, Jesus Rodrigalvarez

et al.

Angewandte Chemie International Edition, Journal Year: 2024, Volume and Issue: unknown

Published: May 21, 2024

Herein, we disclose a new strategy that rapidly and reliably incorporates bromine atoms at distal, secondary C(sp

Language: Английский

Citations

3
Yb-Doped CuY modulates Cu electronic structures for efficient oxidation of anisole to guaiacol DOI Creative Commons
Hanghang Zhang, Gang Xu

RSC Advances, Journal Year: 2025, Volume and Issue: 15(13), P. 9899 - 9909

Published: Jan. 1, 2025

Yb-Doped CuY catalysts enhance the electronic structure of copper for efficient hydrogen peroxide oxidation anisole to guaiacol, achieving improved conversion rates and selectivity.

Language: Английский

Citations

0
Directed C(sp3)-H Arylation of Free α-Aminophosphonates: Dual Models Exploration via Palladium Catalysis DOI

Li−Na Yi,

Tao Zhao,

Jinghan Bu

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(19), P. 4132 - 4136

Published: May 8, 2024

In this report, we present the dual activation models for transient directing group-directed and amino-self-directed Pd-catalyzed α-aminophosphonate side-chain C(sp3)-H arylation. Both strategies showed facile, efficient, single regioselectivity in reaction between free α-aminophosphonates aryl iodides. Furthermore, modification of amino late-stage functionalization C(sp3)-P bond from products indicates potential applications α-aminophosphonates.

Language: Английский

Citations

2
Manganese/Enzyme Sequential Catalytic Pathway for the Production of Optically Active γ-Functionalized Alcohols DOI
Meng Deng, Jiaqi Yang, Z.-G. Kong

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(12), P. 9103 - 9109

Published: June 6, 2024

A brief, practical catalytic process for the production of optically active γ-functionalized alcohols from relevant alkenes has been developed by using a robust Mn(III)/air/(Me2SiH)2O system combined with lipase-catalyzed kinetic resolution. This approach demonstrates exceptional tolerance toward proximal functional groups present on alkenes, enabling achievement high yields and exclusive enantioselectivity. Under this sequential system, chiral alkene precursors can also be converted into related acetates as separable single enantiomers.

Language: Английский

Citations

2
Advances in Transition Metal Catalysis and Organocatalysis Approaches towards Asymmetric Synthesis of β-Amino Acid Derivatives DOI

Farrukh Sajjad,

Shuyue Zhang, Ming‐Hua Xu

et al.

Synthesis, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 16, 2024

Abstract The stereoselective synthesis of β-amino acids has attracted major attention among the synthetic community in recent years. This review provides an overview important advances chiral acid over past decade. It covers development enantioselective methods using transition-metal complexes or organocatalysts, mainly including catalytic asymmetric hydrogenation, Mannich reaction, multicomponent reactions diazo compounds, and conjugate addition. Additionally, optically active by other approaches are also summarized. 1 Introduction 2 Strategies towards Asymmetric Synthesis β-Amino Acids 2.1 Hydrogenation 2.2 Reaction 2.3 Conjugate Addition 2.4 Multicomponent Reactions 2.5 Miscellaneous 2.5.1 from Chiral Amines 2.5.2 Isoxazolidinones 2.5.3 Other Methodologies 3 Summary Outlook

Language: Английский

Citations

2
Palladium catalyzed C(sp3)–H bond activation of free carboxylic acids: An adventure of ligand evolution DOI
Dong Li,

Xiao-Bao He,

Liang Jin

et al.

Tetrahedron Letters, Journal Year: 2024, Volume and Issue: 138, P. 154951 - 154951

Published: Feb. 7, 2024

Language: Английский

Citations

1