Recent advances in asymmetric P(III)/P(V) = O redox catalysis DOI
Changmin Xie,

Guzhou Chen,

Chen‐Guo Feng

et al.

Tetrahedron Letters, Journal Year: 2024, Volume and Issue: unknown, P. 155337 - 155337

Published: Oct. 1, 2024

Language: Английский

Selective Synthesis of Mono- and Bis-Phosphorylated (Dihydro)pyrans via TMSCl-Mediated Cascade Phosphorylation Cycloisomerization of Enynones DOI
Yi‐Feng Qiu, Qiang Wang,

Jian-He Cao

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 26, 2024

A chlorotrimethylsilane (TMSCl)-mediated cascade phosphorylation and cycloisomerization of enynones with diphenylphosphine oxides is presented. This methodology enables the highly selective synthesis monophosphorylated 2

Language: Английский

Citations

3
Lewis Acid-Mediated Deoxygenative Synthesis of Trivalent Sterically Hindered Phosphines from Aldehydes DOI
Xiaoqiang Wu,

Abuduwaili Alimu,

Wei Zhong

et al.

Organic Letters, Journal Year: 2025, Volume and Issue: unknown

Published: May 29, 2025

The efficient synthesis of trisubstituted trivalent phosphines remains challenging. Herein, we report a novel approach for rapid construction these compounds from aldehydes under Lewis acid-mediated conditions. By using sterically hindered disubstituted phosphines, can undergo deoxygenative reaction to afford phosphorus compounds. This modular and practical method is characterized by operational simplicity, broad substrate scope, excellent functional group tolerance, which holds great potential applications in organic synthesis.

Language: Английский

Citations

0
Chiral-Bisphosphine-Catalyzed Asymmetric Staudinger/Aza-Wittig Reaction: Development, Mechanism Study, and Synthetic Application DOI
Yefeng Tang, Hongzhi Yang,

Truc Quynh Nguyen

et al.

Synlett, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 22, 2024

Abstract The enantioselective desymmetrization of 2,2-disubstituted cyclohexane-1,3-diones has been realized through an unprecedented chiral-bisphosphine-catalyzed asymmetric Staudinger/aza-Wittig reaction. key to this work’s success lies in utilizing electronically rich and sterically hindered chiral bisphosphine reagent, namely DuanPhos, as a catalyst. In addition, unique reductive system was established address the requisite PIII/PV = O redox cycle. mechanism reaction elucidated combined computational experimental studies. Several crinine-type amaryllidaceae alkaloids have synthesized concisely, hinging on newly developed methodology.

Language: Английский

Citations

1
Recent advances in asymmetric P(III)/P(V) = O redox catalysis DOI
Changmin Xie,

Guzhou Chen,

Chen‐Guo Feng

et al.

Tetrahedron Letters, Journal Year: 2024, Volume and Issue: unknown, P. 155337 - 155337

Published: Oct. 1, 2024

Language: Английский

Citations

0