Green Chemistry, Journal Year: 2020, Volume and Issue: 23(1), P. 307 - 313
Published: Dec. 11, 2020
Malleable polyurethane (PU) foams bearing disulfide bond were fabricated using conventional foaming technology and could be thermally recycled into PU films through compression molding.
Language: Английский
Angewandte Chemie International Edition, Journal Year: 2022, Volume and Issue: 61(39)
Published: Aug. 4, 2022
Chemical recycling of synthetic polymers offers a solution for developing sustainable plastics and materials. Here we show that two types dynamic covalent chemistry can be orthogonalized in solvent-free polymer network thus enable chemically recyclable crosslinked material. Using simple acylhydrazine-based 1,2-dithiolane as the starting material, disulfide-mediated reversible polymerization acylhydrazone-based crosslinking combined one-pot reaction, resulting mechanically robust, tough, processable The bonds both backbones crosslinkers endow with depolymerization capability under mild conditions and, importantly, virgin-quality monomers recovered separated. This proof-of-concept study opportunities to design materials based on toolbox.
Language: Английский
Citations
79
Macromolecules, Journal Year: 2022, Volume and Issue: 55(6), P. 2243 - 2251
Published: March 2, 2022
Castor oil (CO)-derived polyurethanes (PUs), denoted CPUs, are drastically limited because they cannot be reprocessed, reshaped, or recycled and show low strength, poor toughness, insufficient functionality due to their permanently cross-linked structure with a high cross-link density soft backbone. Herein, we developed novel reversible piperazine–urea bonds (PaUBs) from inexpensive piperazines isocyanates incorporated the PaUBs into CPUs fabricate sustainable reprocessable poly(urethane urea) covalent adaptable networks (CANs). We synthesized CANs CO, N-(2-hydroxyethyl) piperazine (HEP), 4-methylenedicyclohexyl diisocyanate (HMDI) via catalyst- solvent-free approach. The showed variable tensile behavior over wide range elastomer tough hard plastics. They also exhibited excellent malleability, stable reprocessability, multiple recyclability, in which original properties were recovered after several thermal recycling remolding cycles. possessed shape memory performance reconfigurability, allowing them reprocessed various complex shapes without using mold. advanced based on dynamic have great potential application as alternatives traditional fossil-derived elastomers
Language: Английский
Citations
71
Nature, Journal Year: 2023, Volume and Issue: 619(7969), P. 293 - 299
Published: June 7, 2023
Language: Английский
Citations
67
Chemical Reviews, Journal Year: 2023, Volume and Issue: 123(12), P. 7782 - 7853
Published: May 15, 2023
The high selectivity and affinity of antibodies toward their antigens have made them a highly valuable tool in disease therapy, diagnosis, basic research. A plethora chemical genetic approaches been devised to make accessible more "undruggable" targets equipped with new functions illustrating or regulating biological processes precisely. In this Review, addition introducing how naked various antibody conjugates (such as antibody-drug conjugates, antibody-oligonucleotide antibody-enzyme etc.) work therapeutic applications, special attention has paid chemistry tools helped optimize the outcome (i.e., enhanced efficacy reduced side effects) facilitate multifunctionalization antibodies, focus on emerging fields such targeted protein degradation, real-time live-cell imaging, catalytic labeling decaging spatiotemporal control well engagement inside cells. With advances modern biotechnology, well-designed derivatives via size miniaturization together efficient delivery systems emerged, which gradually improved our understanding important paved way pursue novel for potential treatments diseases.
Language: Английский
Citations
66
ACS Macro Letters, Journal Year: 2023, Volume and Issue: 12(6), P. 787 - 793
Published: May 23, 2023
Pressure-sensitive adhesives (PSAs) based on poly(acrylate) chemistry are common in a wide variety of applications, but the absence backbone degradability causes issues with recycling and sustainability. Here, we report strategy to create degradable PSAs using simple, scalable, functional 1,2-dithiolanes as drop-in replacements for traditional acrylate comonomers. Our key building block is α-lipoic acid, natural, biocompatible, commercially available antioxidant found various consumer supplements. α-Lipoic acid its derivative ethyl lipoate efficiently copolymerize n-butyl under conventional free-radical conditions leading high-molecular-weight copolymers (Mn > 100 kg mol-1) containing tunable concentration disulfide bonds along backbone. The thermal viscoelastic properties these materials practically indistinguishable from nondegradable analogues, significant reduction molecular weight realized upon exposure reducing agents such tris (2-carboxyethyl) phosphine (e.g., Mn = 198 mol-1 → 2.6 mol-1). By virtue thiol chain ends produced after cleavage, degraded oligomers can be further cycled between high low weights through oxidative repolymerization reductive degradation. Transforming otherwise persistent poly(acrylates) into recyclable simple versatile could play pivotal role improving sustainability contemporary adhesives.
Language: Английский
Citations
56
Angewandte Chemie International Edition, Journal Year: 2023, Volume and Issue: 62(11)
Published: Jan. 5, 2023
Poly(1,2-dithiolane)s are a family of intrinsically recyclable polymers due to their dynamic covalent disulfide linkages. Despite the common use thiolate-initiated anionic ring-opening polymerization (ROP) under basic condition, cationic ROP is still not exploited. Here we report that bond can act as proton acceptor, being protonated by acids form sulfonium cations, which efficiently initiate 1,2-dithiolanes and result in high-molecular-weight (over 1000 kDa) poly(disulfide)s. The reaction be triggered adding catalytic amounts non-coordinating anion salts, completed few minutes at room temperature. acidic conditions allow applicability for monomers. Importantly, condition open air without inert protection, enabling nearly quantitative chemical recycling from bulk materials original
Language: Английский
Citations
52
Journal of the American Chemical Society, Journal Year: 2023, Volume and Issue: 145(41), P. 22728 - 22734
Published: Oct. 9, 2023
Here, we present the synthesis and characterization of statistical block copolymers containing α-lipoic acid (LA) using reversible addition-fragmentation chain-transfer (RAFT) polymerization. LA, a readily available nutritional supplement, undergoes efficient radical ring-opening copolymerization with vinyl monomers in controlled manner predictable molecular weights low molar-mass dispersities. Because lipoic diads resulting include disulfide bonds, these materials efficiently rapidly degrade when exposed to mild reducing agents such as tris(2-carboxyethyl)phosphine (Mn = 56 → 3.6 kg mol-1). This scalable versatile polymerization method affords facile way synthesize degradable polymers architectures, weights, dispersities from acid, commercially renewable monomer.
Language: Английский
Citations
48
ACS Applied Materials & Interfaces, Journal Year: 2023, Volume and Issue: 15(15), P. 19447 - 19458
Published: April 10, 2023
Liquid-free ionic conductive elastomers (ICEs) are ideal materials for wearable strain sensors in increasingly flexible electronic devices. However, developing recyclable ICEs with high elasticity, self-healability, and recyclability is still a great challenge. In this study, we fabricated series of novel by situ polymerization lipoic acid (LA) poly(acrylic acid) (PAA) solution cross-linking coordination bonding hydrogen bonding. One the obtained dynamically cross-linked interlocking double-network ICEs, PLA-PAA4-1% ICE, showed excellent mechanical properties, elasticity (90%) stretchability (610%), as well rapid self-healability (mechanical self-healing within 2 h electrical recovery 0.3 s). The ICE was used sensor possessed linear sensitivity highly cyclic stability, effectively monitoring diverse human motions both stretched compressed deformations. Notably, can be fully recycled reused new without any structure change or degradation performance. This work provided viable path to fabricate solving two contradictions property stability recyclability. We believe that superior overall performance feasible fabrication make developed hold promise multifunctional practical applications devices humanoid robotics.
Language: Английский
Citations
43
Nature, Journal Year: 2024, Volume and Issue: 629(8014), P. 1069 - 1074
Published: May 15, 2024
The additive manufacturing of photopolymer resins by means vat photopolymerization enables the rapid fabrication bespoke 3D-printed parts. Advances in methodology have continually improved resolution and speed, yet both process design resin technology remained largely consistent since its inception 1980s
Language: Английский
Citations
42
Science, Journal Year: 2024, Volume and Issue: 385(6711), P. 877 - 883
Published: Aug. 22, 2024
Polymer adhesives play an important role in many medical, consumer, and industrial products. Polymers of α-lipoic acid (αLA) have the potential to fulfill need for versatile environmentally friendly adhesives, but their performance is plagued by spontaneous depolymerization. We report a family stabilized αLA polymer that can be tailored variety medical or nonmedical uses sustainably sourced recycled closed-loop manner. Minor changes monomer composition afforded pressure-sensitive adhesive functions well dry wet conditions, as structural with strength equivalent conventional epoxies. surgical superglue successfully sealed murine amniotic sac ruptures, increasing fetal survival from 0 100%.
Language: Английский
Citations
32