Molecular Pharmaceutics,
Journal Year:
2021,
Volume and Issue:
18(3), P. 1229 - 1237
Published: Jan. 11, 2021
Recently,
supramolecular
coordination
complexes
(SCCs)
based
on
photosensitizers
as
bridging
ligands
have
attracted
great
attention
in
cancer
therapy
owing
to
their
synergistic
effect
between
photodynamic
(PDT)
and
chemotherapy.
Herein,
a
highly
emissive
platinum
triangle
BTZPy-Pt
novel
type
of
photosensitizer
BTZPy
with
thermally
activated
delayed
fluorescence
(TADF)
was
fabricated.
The
exhibited
strong
luminescence
emission
the
visible
range
high
quantum
yields
(quantum
(QYs)
for
were
about
78
62%
ethanol
solutions,
respectively).
Additionally,
had
been
proved
be
an
excellent
superior
1O2
generation
capability
(the
yield
reached
up
ca.
95%)
PDT.
By
combination
phototoxicity
antitumor
activity
Pt
center,
demonstrated
efficient
anticancer
performance
toward
HeLa
cells
(IC50:
0.5
μg
mL–1).
This
study
not
only
provides
blueprint
fabricate
new
types
but
also
paves
way
design
SCCs
European Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
27(14)
Published: March 12, 2024
Abstract
Aromatic
architectures
able
to
capture,
store
and
release
singlet
oxygen
have
sparked
the
interest
of
scientific
community
as
an
attractive
strategy
generate
oxygen.
Among
these
structures,
anthracenes
are
efficient
batteries
with
applications
in
various
fields
such
chemistry,
materials
science
or
medicine.
Until
now,
studies
mainly
focused
on
symmetrical
9,10‐disubstituted
bearing
(hetero)aryl
groups
substituted
alkyne
motifs.
In
this
work,
we
investigated
unsymmetrical
anthracene
molecules
explore
their
propensity
trap
Kinetic
confirmed
impact
electron‐rich
electron‐deficient
substituents
photooxygenation
step
triggered
by
thermolysis
endoperoxides.
Molecular Pharmaceutics,
Journal Year:
2021,
Volume and Issue:
18(3), P. 1229 - 1237
Published: Jan. 11, 2021
Recently,
supramolecular
coordination
complexes
(SCCs)
based
on
photosensitizers
as
bridging
ligands
have
attracted
great
attention
in
cancer
therapy
owing
to
their
synergistic
effect
between
photodynamic
(PDT)
and
chemotherapy.
Herein,
a
highly
emissive
platinum
triangle
BTZPy-Pt
novel
type
of
photosensitizer
BTZPy
with
thermally
activated
delayed
fluorescence
(TADF)
was
fabricated.
The
exhibited
strong
luminescence
emission
the
visible
range
high
quantum
yields
(quantum
(QYs)
for
were
about
78
62%
ethanol
solutions,
respectively).
Additionally,
had
been
proved
be
an
excellent
superior
1O2
generation
capability
(the
yield
reached
up
ca.
95%)
PDT.
By
combination
phototoxicity
antitumor
activity
Pt
center,
demonstrated
efficient
anticancer
performance
toward
HeLa
cells
(IC50:
0.5
μg
mL–1).
This
study
not
only
provides
blueprint
fabricate
new
types
but
also
paves
way
design
SCCs
