Profiling signaling mediators for cell-cell interactions and communications with microfluidics-based single-cell analysis tools DOI Creative Commons
Shuai Yuan, Peng Zhang, Feng Zhang

et al.

iScience, Journal Year: 2024, Volume and Issue: 28(1), P. 111663 - 111663

Published: Dec. 20, 2024

Language: Английский

Artificial intelligence-enabled multipurpose smart detection in active-matrix electrowetting-on-dielectric digital microfluidics DOI Creative Commons
Z.J. Jia, Chunyu Chang, Siyi Hu

et al.

Microsystems & Nanoengineering, Journal Year: 2024, Volume and Issue: 10(1)

Published: Sept. 27, 2024

Language: Английский

Citations

5
Droplet-Based Microfluidics with Mass Spectrometry for Microproteomics DOI Creative Commons
Hang Li,

Yudan Ma,

Rongxin Fu

et al.

Engineering, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 1, 2024

Language: Английский

Citations

4
Trends in Mass Spectrometry-Based Single-Cell Proteomics DOI

Ximena Sanchez-Avila,

Raphaela Menezes de Oliveira, Siqi Huang

et al.

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 16, 2025

InfoMetrics Analytical ChemistryASAPArticle CiteCitationCitation and abstractCitation referencesMore citation options ShareShare onFacebookXWeChatLinkedInRedditEmailBlueskyJump toExpandCollapse ReviewMarch 16, 2025Trends in Mass Spectrometry-Based Single-Cell ProteomicsClick to copy article linkArticle link copied!Ximena Sanchez-AvilaXimena Sanchez-AvilaDepartment of Chemistry Biochemistry, Brigham Young University, Provo, Utah 84602, United StatesMore by Ximena Sanchez-AvilaView BiographyRaphaela M. de OliveiraRaphaela OliveiraDepartment Raphaela OliveiraView BiographySiqi HuangSiqi HuangDepartment Siqi HuangView BiographyChao WangChao WangDepartment Chao WangView Biographyhttps://orcid.org/0009-0008-6197-2985Ryan T. Kelly*Ryan KellyDepartment States*Email: [email protected]More Ryan KellyView Biographyhttps://orcid.org/0000-0002-3339-4443Other Access OptionsAnalytical ChemistryCite this: Anal. Chem. 2025, XXXX, XXX, XXX-XXXClick citationCitation copied!https://pubs.acs.org/doi/10.1021/acs.analchem.5c00661https://doi.org/10.1021/acs.analchem.5c00661Published March 2025 Publication History Received 28 January 2025Accepted February 2025Revised 23 2025Published online 16 2025review-article© American Chemical SocietyRequest reuse permissionsACS Publications© SocietySubjectswhat are subjects Article automatically applied from the ACS Subject Taxonomy describe scientific concepts themes article. Cells Isolation spectrometry Peptides proteins Sample preparation Note: In lieu an abstract, this is article's first page. Read To access article, please review available below. Get instant Purchase for 48 hours. Check out below using your ID or as a guest. Restore my guest Recommended through Your Institution You may have institution. institution does not content. Add change let them know you'd like include access. Through Recommend Name Loading Institutional Login Options... Change Explore subscriptions institutions Log with if you previously purchased it member benefits. hours $48.00 cart Checkout Cited By Click section linkSection copied!This has yet been cited other publications.Download PDF e-AlertsGet e-AlertsAnalytical copied!https://doi.org/10.1021/acs.analchem.5c00661Published 2025© permissionsArticle Views6Altmetric-Citations-Learn about these metrics closeArticle Views COUNTER-compliant sum full text downloads since November 2008 (both HTML) across all individuals. These regularly updated reflect usage leading up last few days.Citations number articles citing calculated Crossref daily. Find more information counts.The Altmetric Attention Score quantitative measure attention that research received online. Clicking on donut icon will load page at altmetric.com additional details score social media presence given how calculated.Recommended Articles

Language: Английский

Citations

0
Low temperature polysilicon pixel circuits for active-matrix digital microfluidic chips DOI
Shengzhe Jiang, Dongping Wang, Hanbin Ma

et al.

Displays, Journal Year: 2025, Volume and Issue: unknown, P. 103048 - 103048

Published: March 1, 2025

Citations

0
Dynamic whole genome amplification using digital microfluidics for single-cell sequencing DOI
Qingyu Ruan,

Changrui Shi,

Xiaoye Lin

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 162099 - 162099

Published: March 1, 2025

Language: Английский

Citations

0
Light-induced targeting enables proteomics on endogenous condensates DOI Creative Commons
Choongman Lee,

Andrea Quintana,

Ida Suppanz

et al.

Cell, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 1, 2024

Language: Английский

Citations

2
Democratizing Digital Microfluidics by a Cloud-based Design and Manufacturing Platform DOI
Qining Wang,

Eric Hyunsung Cho,

Jia Li

et al.

Lab on a Chip, Journal Year: 2024, Volume and Issue: 24(19), P. 4536 - 4548

Published: Jan. 1, 2024

Akin to the impact that digital microelectronics had on electronic devices for information technology, microfluidics (DMF) was anticipated transform fluidic lab-on-a-chip (LoC) applications. However, despite a wealth of research and publications, electrowetting-on-dielectric (EWOD) DMF has not achieved wide adoption, commercialization been painfully slow. By identifying technological resource hurdles in developing chip control systems as culprit, we envision democratizing by building standardized design manufacturing platform. To achieve this vision, introduce proof-of-concept cloud platform empowers any user design, obtain, operate chips (https://edroplets.org). For establish web-based EWOD with layout rules automated wire routing. manufacturing, build fabricate four types (

Language: Английский

Citations

1
Digital Microfluidics for Sample Preparation in Low‐Input Proteomics DOI Creative Commons

Max K. Steinbach,

Jan Leipert,

Theo Matzanke

et al.

Small Methods, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 29, 2024

Abstract Low‐input proteomics, also referred to as micro‐ or nanoproteomics, has become increasingly popular it allows one elucidate molecular processes in rare biological materials. A major prerequisite for the analytics of minute protein amounts, e.g., derived from low cell numbers, down single cells, is availability efficient sample preparation methods. Digital microfluidics (DMF), a technology allowing handling and manipulation liquid volumes, recently been shown be powerful versatile tool address challenges low‐input proteomics. Here, an overview provided on recent advances proteomics using DMF. In particular, capability DMF isolate proteomes cells small model organisms, perform all necessary chemical steps, such denaturation proteolytic digestion on‐chip, are highlighted. Additionally, prerequisites making these steps compatible with follow‐up analytical methods chromatography‐mass spectrometry will discussed.

Language: Английский

Citations

1
Profiling signaling mediators for cell-cell interactions and communications with microfluidics-based single-cell analysis tools DOI Creative Commons
Shuai Yuan, Peng Zhang, Feng Zhang

et al.

iScience, Journal Year: 2024, Volume and Issue: 28(1), P. 111663 - 111663

Published: Dec. 20, 2024

Language: Английский

Citations

0