Impacts of Prediabetes Mellitus Alone or Plus Hypertension on the Coronary Severity and Cardiovascular Outcomes

Hypertension, Journal Year: 2018, Volume and Issue: 71(6), P. 1039 - 1046

Published: April 18, 2018

Whether prediabetes mellitus (Pre-DM) alone or combined with hypertension is an independent risk factor for cardiovascular disease has not been fully clarified. This study aimed to further confirm whether the relation of Pre-DM differs between individuals without hypertension. A total 7121 consecutive patients angina-like chest pain who received coronary angiography were evaluated and 4193 angiography-proven stable, new-onset artery enrolled into study. They divided 3 groups according diabetes status stratified by The severity was assessed number diseased vessels Gensini score. All subjects regularly followed up occurrence composite end points. Comparisons outcomes performed among these groups. During average 11 338 patient-years follow-up, 434 (10.35%) events occurred. No significant difference observed in point normal glucose regulation (both P>0.05). However, when also incorporated as a stratifying factor, risk, clinical prognosis, significantly elevated plus groups, compared reference group blood pressure (all P<0.05). present indicated that disease, increased largely driven coexistence rather than per se.

Language: Английский

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<p>Hypertension and Its Associated Factors Among Type 2 Diabetes Mellitus Patients at Debre Tabor General Hospital, Northwest Ethiopia</p>

Diabetes Metabolic Syndrome and Obesity, Journal Year: 2020, Volume and Issue: Volume 13, P. 1621 - 1631

Published: May 1, 2020

Background: Type 2 diabetes mellitus (T2DM) is associated with a high risk of early mortality and morbidity from hypertension. Even though Ethiopia Africa's first country among the top five in prevalence DM, there paucity data on hypertension its factors patients type mellitus. Therefore, this study aimed to determine at Debre Tabor General Hospital, 2019. Methods Materials: An institution-based cross-sectional was employed 378 T2DM patients. Data were collected using an interviewer-administered questionnaire analyzed by Stata 14. A multivariable logistic regression model used identify Associated declared p < 0.05. Results: The 59.5% (95% CI: 54.5– 64.5). Stage 1 most common (30.95%). odds higher age group 50– 60 years (adjusted ratio (AOR)=2.5, 95% confidence interval (CI) (1.27– 4.90)), urban area (AOR = 2.8, CI (1.08– 7.18)), longer duration =1.16, 1.25)), BMI ≥ 25 kg/m 3.2, (1.71– 5.96)), poor glycemic control 3.0, (1.75– 5.19)), who current cigarette smokers 3.8, (1.98– 14.96)). Conclusion: majority have blood pressure control. Hence, DM care providers other health sector stakeholders work collaboration prevent it through designing appropriate strategies especially for those developing Keywords: hypertension, factors, mellitus,

Language: Английский

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Associations of metabolic disorders with hypertension and cardiovascular disease: recent findings and therapeutic perspectives

Hypertension Research, Journal Year: 2024, Volume and Issue: 47(12), P. 3338 - 3344

Published: May 29, 2024

Language: Английский

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The influence of different forms of apple products on all-cause mortality in patients with hypertension

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 11

Published: Jan. 24, 2025

Objective Apple consumption has a positive effect on human health. Some studies have shown that an appropriate amount of apple intake can reduce the incidence hypertension. However, few investigated whether eating different forms apples same benefits as whole apples. This study is aimed to evaluate all-cause mortality in patients with Methods The included 2,368 All participants were followed up for at least 10 years. Cox regression model was constructed analyze correlation between apple, juice, and sauce Results 3–6 times/week associated 48% reduction risk hypertension (HR = 0.52, 95% CI: 0.37–0.72, p &lt; 0.001). juice 1.02, 0.67–1.56, 0.930) 1.28, 0.59–2.74, 0.531) tended increase death hypertension, although this did not obtain statistically result. Conclusion Moderate reduced whereas may death.

Language: Английский

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The association between multimorbidity and health-related quality of life: a cross-sectional survey among community middle-aged and elderly residents in southern China

Health and Quality of Life Outcomes, Journal Year: 2019, Volume and Issue: 17(1)

Published: June 24, 2019

Multimorbidity is common among the middle-aged and elderly residents. And it associated to reduction of health-related quality life (HRQoL), including physical psychological dimensions. However, there are few studies that have paid attention HRQoL residents with multimorbidity in China. Therefore, this study aims investigate relationships between different patterns adults China.Based on a cross-sectional survey, information regarding 18,137 adults, who were at least 45 years age, was collected through interviews. Self-perceived assessed EQ-5D-3 L instrument, index score calculated using Chinese value set. The Tobit regression used explore impacts groups HRQoL.Of respondents, more than fifth (3773,20.8%) people had multimorbidity. Mean (SD) EQ-5D VAS values 0.95(0.14) 76.02(13.66), respectively. Significant correlations found lower increasing numbers chronic conditions (P < 0.001). Most diseases co-occurred frequently, association hypertension diabetes mellitus strongest (adjusted OR = 3.82). most prevalent disease (5052,27.9%), pair (841,4.6%). Among those high prevalence, effects ranged from pain (adjust b - 0.036 0.008). In patterns, co-occurrence bone 0.039) greatest impact HRQoL.The declines by More should be effect not simply added two diseases, but changes combination. Identifying can provide targeted measures improve HRQoL.

Language: Английский

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Hypertension and type 2 diabetes: lights and shadows about causality

Journal of Human Hypertension, Journal Year: 2019, Volume and Issue: 34(2), P. 91 - 93

Published: Oct. 21, 2019

Language: Английский

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Prevalence and associated factors of hypertension among adults with diabetes mellitus in northern Sudan: a cross-sectional study

BMC Cardiovascular Disorders, Journal Year: 2021, Volume and Issue: 21(1)

Published: April 10, 2021

Abstract Background Hypertension and diabetes mellitus (DM), are highly prevalent worldwide health non-communicable diseases, associated with chronic complications. The co-existence of both conditions accelerates the related complications increases morbidities mortalities. A cross-sectional study was conducted in Nahr an Nil State (River Nile State) Sudan between May August 2018 to identify prevalence hypertension risk factors among patients DM that region. Results median (interquartile) age 1,973 enrolled 58.0 (50.0‒65.0) years, 818 (45.6%) were males. duration 5.0 (3.0‒9.0) years. Of participants, 21.7%, 1.3%, 37.1%, 39.9% normal weight, underweight, overweight, obese, respectively. 854 (47.6%) also had hypertension. Logistic regression analyses showed elderly (adjusted odds ratio [AOR] = 1.03, 95%; confidence interval [CI] 1.02‒1.04), males (AOR 2.96, CI 2.15‒4.07), employed 1.92, 1.38‒2.70), obese 1.59, 1.21‒2.08), diabetic foot (DF) 2.45, 1.72‒3.47) at higher for Conversely, Type 2 (T2DM) 0.63, 0.50‒0.80) lower There no significant association uncontrolled DM, Conclusion This a high DM. Notably, older age, male gender, employment, DF, obesity predictors

Language: Английский

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Recent understandings about hypertension management in type 2 diabetes: What are the roles of SGLT2 inhibitor, GLP-1 receptor agonist, and finerenone?

Hypertension Research, Journal Year: 2023, Volume and Issue: 46(8), P. 1892 - 1899

Published: May 31, 2023

Language: Английский

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Determining the Prevalence of Primary Aldosteronism in Patients With New-Onset Type 2 Diabetes and Hypertension

The Journal of Clinical Endocrinology & Metabolism, Journal Year: 2020, Volume and Issue: 105(4), P. 1079 - 1085

Published: March 12, 2020

Abstract Context Despite a high prevalence of hypertension in diabetes and close relationship between primary aldosteronism (PA) glucose metabolism, few study concerns the PA with hypertension. Objective This aimed to detect patients new-onset type 2 (T2D) explore association diabetes. Methods A total 256 outpatients T2D were screened for PA. Plasma aldosterone concentration (PAC), plasma renin activity (PRA) measured. Patients an ratio (ARR) ≥ 30 ng/dL/ng/mL/h PAC 15 ng/dL underwent confirmatory captopril challenge test (CCT) The diagnostic criteria were, after CCT, (1) decreased &lt; 30%, (2) ARR maintained ng/dL/ng/mL/h, (3) was 11 ng/dL. Results Of consecutive patients, 99 (39%) positive screening test, 49 (19%) diagnosed Compared those groups (screening −) B +, CCT −), group C (diagnosed PA) had higher percentage systolic blood pressure 160 mmHg, less family history hypertension, lower serum potassium. levels, but PRA than A. Homeostatic model assessment insulin resistance (HOMA-IR) positively associated level among diabetic patients. Conclusion is at least 19%. Higher may be related

Language: Английский

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The Influence of Mat Pilates Training on Cardiometabolic Risk Factors in Postmenopausal Women with Single or Multiple Cardiometabolic Diseases

International Journal of Environmental Research and Public Health, Journal Year: 2025, Volume and Issue: 22(1), P. 56 - 56

Published: Jan. 2, 2025

This study compared the effects of Mat Pilates training on cardiovascular risk markers in postmenopausal women with single or multiple cardiometabolic conditions. Forty-four were divided into single-condition (SINGLE; n = 20) and multiple-condition (MULTI; 24) groups. Both groups completed three times per week for 12 weeks. Measurements resting blood pressure, body composition, dietary intake, taken before after intervention. A Generalized Estimating Equation was used hypothesis testing. MULTI presented higher mass, BMI, fat waist circumference. Systolic pressure decreased more SINGLE (-13 ± 15 mmHg) than (-3 16 mmHg, p interaction 0.016 diastolic reductions both (SINGLE: -9 mmHg; MULTI: -2 11 0.053). Triglycerides only (-40 98 mg/dL vs. +31 70 MULTI, 0.006), while no significant changes observed cholesterol levels. Adiponectin levels -1.5 16.3; -9.3 12.4 µg/dL, time 0.015). Glycated hemoglobin over (-0.3 0.5% SINGLE, -0.5 0.6% < 0.001), glucose. These findings suggest that may be effective reducing factors a condition to those

Language: Английский

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