The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic

Nature Reviews Gastroenterology & Hepatology, Journal Year: 2014, Volume and Issue: 11(8), P. 506 - 514

Published: June 10, 2014

Probiotics are widely regarded as live microorganisms that, when administered in sufficient amounts, confer a health benefit, but guidance is needed on the most appropriate use of term. This Consensus Statement outlines recommendations for scope and definition term 'probiotic' determined by an expert panel convened International Scientific Association Prebiotics October 2013. An was 2013 (ISAPP) to discuss field probiotics. It now 13 years since probiotics 12 after guidelines were published regulators, scientists industry Food Agriculture Organization United Nations WHO (FAO/WHO). The FAO/WHO probiotic—"live which adequate amounts benefit host"—was reinforced relevant sufficiently accommodating current anticipated applications. However, inconsistencies between Expert Consultation Report Guidelines clarified take into account advances science A more precise will be useful guide clinicians consumers differentiating diverse products market. document represents conclusions ISAPP consensus meeting probiotic.

Language: Английский

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Global aetiology and epidemiology of type 2 diabetes mellitus and its complications

Nature Reviews Endocrinology, Journal Year: 2017, Volume and Issue: 14(2), P. 88 - 98

Published: Dec. 8, 2017

Language: Английский

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Role of the Microbiota in Immunity and Inflammation

Cell, Journal Year: 2014, Volume and Issue: 157(1), P. 121 - 141

Published: March 1, 2014

Language: Английский

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Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association

Circulation, Journal Year: 2022, Volume and Issue: 145(8)

Published: Jan. 26, 2022

The American Heart Association, in conjunction with the National Institutes of Health, annually reports most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, weight) factors (cholesterol, blood pressure, glucose control) that contribute health. Statistical Update presents latest data on a range major clinical circulatory disease conditions (including congenital rhythm disorders, subclinical atherosclerosis, coronary failure, valvular venous peripheral artery disease) associated outcomes quality care, procedures, economic costs).

Language: Английский

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Richness of human gut microbiome correlates with metabolic markers

Nature, Journal Year: 2013, Volume and Issue: 500(7464), P. 541 - 546

Published: Aug. 27, 2013

Language: Английский

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Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

Proceedings of the National Academy of Sciences, Journal Year: 2013, Volume and Issue: 110(22), P. 9066 - 9071

Published: May 13, 2013

Obesity and type 2 diabetes are characterized by altered gut microbiota, inflammation, barrier disruption. Microbial composition the mechanisms of interaction with host that affect function during obesity have not been elucidated. We recently isolated Akkermansia muciniphila , which is a mucin-degrading bacterium resides in mucus layer. The presence this inversely correlates body weight rodents humans. However, precise physiological roles played metabolic disorders unknown. This study demonstrated abundance A. decreased obese diabetic mice. also observed prebiotic feeding normalized abundance, correlated an improved profile. In addition, we treatment reversed high-fat diet-induced disorders, including fat-mass gain, endotoxemia, adipose tissue insulin resistance. administration increased intestinal levels endocannabinoids control barrier, peptide secretion. Finally, all these effects required viable because heat-killed cells did improve profile or layer thickness. summary, provides substantial insight into intricate bacterial (i.e., ) regulation cross-talk between microbiota. These results provide rationale for development uses human colonizer prevention its associated disorders.

Language: Английский

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Gut microbiota in human metabolic health and disease

Nature Reviews Microbiology, Journal Year: 2020, Volume and Issue: 19(1), P. 55 - 71

Published: Sept. 4, 2020

Language: Английский

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The gut microbiota — masters of host development and physiology

Nature Reviews Microbiology, Journal Year: 2013, Volume and Issue: 11(4), P. 227 - 238

Published: Feb. 25, 2013

Language: Английский

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Proteobacteria: microbial signature of dysbiosis in gut microbiota

Trends in biotechnology, Journal Year: 2015, Volume and Issue: 33(9), P. 496 - 503

Published: July 22, 2015

Language: Английский

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The Human Intestinal Microbiome in Health and Disease

New England Journal of Medicine, Journal Year: 2016, Volume and Issue: 375(24), P. 2369 - 2379

Published: Dec. 14, 2016

The large majority of studies on the role microbiome in pathogenesis disease are correlative and preclinical; several have influenced clinical practice.

Language: Английский

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