Decoupling of mechanical properties and ionic conductivity in supramolecular lithium ion conductors DOI Creative Commons
David G. Mackanic, Xuzhou Yan, Qiuhong Zhang

et al.

Nature Communications, Journal Year: 2019, Volume and Issue: 10(1)

Published: Nov. 26, 2019

The emergence of wearable electronics puts batteries closer to the human skin, exacerbating need for battery materials that are robust, highly ionically conductive, and stretchable. Herein, we introduce a supramolecular design as an effective strategy overcome canonical tradeoff between mechanical robustness ionic conductivity in polymer electrolytes. lithium ion conductor utilizes orthogonally functional H-bonding domains ion-conducting create electrolyte with unprecedented toughness (29.3 MJ m-3) high (1.2 × 10-4 S cm-1 at 25 °C). Implementation binder material allows creation stretchable lithium-ion electrodes strain capability over 900% via conventional slurry process. nature these components enables intimate bonding electrode-electrolyte interface. Combination leads capacity 1.1 mAh cm-2 functions even when stretched 70% strain. method reported here decoupling from properties opens promising route high-toughness transport energy storage applications.

Language: Английский

Pursuing prosthetic electronic skin DOI
Alex Chortos, Jia Liu, Zhenan Bao

et al.

Nature Materials, Journal Year: 2016, Volume and Issue: 15(9), P. 937 - 950

Published: July 4, 2016

Language: Английский

Citations

2129
Recent Advances in Flexible and Stretchable Bio‐Electronic Devices Integrated with Nanomaterials DOI
Suji Choi, Hyunjae Lee, Roozbeh Ghaffari

et al.

Advanced Materials, Journal Year: 2016, Volume and Issue: 28(22), P. 4203 - 4218

Published: Jan. 18, 2016

Flexible and stretchable electronics optoelectronics configured in soft, water resistant formats uniquely address seminal challenges biomedicine. Over the past decade, there has been enormous progress materials, designs, manufacturing processes for flexible/stretchable system subcomponents, including transistors, amplifiers, bio‐sensors, actuators, light emitting diodes, photodetector arrays, photovoltaics, energy storage elements, bare die integrated circuits. Nanomaterials prepared using top‐down processing approaches synthesis‐based bottom‐up methods have helped resolve intrinsic mechanical mismatch between rigid/planar devices soft/curvilinear biological structures, thereby enabling a broad range of non‐invasive, minimally invasive, implantable systems to Integration therapeutic functional nanomaterials with soft bioelectronics demonstrates therapeutics combination unconventional diagnostics capabilities. Recent advances devices, are reviewes, representative examples that highlight utility advanced medical therapies.

Language: Английский

Citations

1014
An Integrated Brain-Machine Interface Platform With Thousands of Channels DOI Creative Commons

Elon Musk

Journal of Medical Internet Research, Journal Year: 2019, Volume and Issue: 21(10), P. e16194 - e16194

Published: Oct. 14, 2019

Brain-machine interfaces hold promise for the restoration of sensory and motor function treatment neurological disorders, but clinical brain-machine have not yet been widely adopted, in part, because modest channel counts limited their potential. In this white paper, we describe Neuralink's first steps toward a scalable high-bandwidth interface system. We built arrays small flexible electrode "threads," with as many 3072 electrodes per array distributed across 96 threads. also neurosurgical robot capable inserting six threads (192 electrodes) minute. Each thread can be individually inserted into brain micron precision avoidance surface vasculature targeting specific regions. The is packaged implantable device that contains custom chips low-power on-board amplification digitization: package channels occupies less than 23×18.5×2 mm

Language: Английский

Citations

823
Technology Roadmap for Flexible Sensors DOI Creative Commons
Yifei Luo, Mohammad Reza Abidian, Jong‐Hyun Ahn

et al.

ACS Nano, Journal Year: 2023, Volume and Issue: 17(6), P. 5211 - 5295

Published: March 9, 2023

Humans rely increasingly on sensors to address grand challenges and improve quality of life in the era digitalization big data. For ubiquitous sensing, flexible are developed overcome limitations conventional rigid counterparts. Despite rapid advancement bench-side research over last decade, market adoption remains limited. To ease expedite their deployment, here, we identify bottlenecks hindering maturation propose promising solutions. We first analyze achieving satisfactory sensing performance for real-world applications then summarize issues compatible sensor-biology interfaces, followed by brief discussions powering connecting sensor networks. Issues en route commercialization sustainable growth sector also analyzed, highlighting environmental concerns emphasizing nontechnical such as business, regulatory, ethical considerations. Additionally, look at future intelligent sensors. In proposing a comprehensive roadmap, hope steer efforts towards common goals guide coordinated development strategies from disparate communities. Through collaborative efforts, scientific breakthroughs can be made sooner capitalized betterment humanity.

Language: Английский

Citations

720
Soft and elastic hydrogel-based microelectronics for localized low-voltage neuromodulation DOI
Yuxin Liu, Jia Liu, Shucheng Chen

et al.

Nature Biomedical Engineering, Journal Year: 2019, Volume and Issue: 3(1), P. 58 - 68

Published: Jan. 2, 2019

Language: Английский

Citations

661
Materials and technologies for soft implantable neuroprostheses DOI
Stéphanie P. Lacour, Grégoire Courtine, Jochen Guck

et al.

Nature Reviews Materials, Journal Year: 2016, Volume and Issue: 1(10)

Published: Sept. 27, 2016

Language: Английский

Citations

602
Novel electrode technologies for neural recordings DOI
Guosong Hong, Charles M. Lieber

Nature reviews. Neuroscience, Journal Year: 2019, Volume and Issue: 20(6), P. 330 - 345

Published: March 4, 2019

Language: Английский

Citations

591
Nano-Bioelectronics DOI
Anqi Zhang, Charles M. Lieber

Chemical Reviews, Journal Year: 2015, Volume and Issue: 116(1), P. 215 - 257

Published: Dec. 21, 2015

Nano-bioelectronics represents a rapidly expanding interdisciplinary field that combines nanomaterials with biology and electronics and, in so doing, offers the potential to overcome existing challenges bioelectronics. In particular, shrinking electronic transducer dimensions nanoscale making their properties appear more biological can yield significant improvements sensitivity biocompatibility thereby open up opportunities fundamental healthcare. This review emphasizes recent advances nano-bioelectronics enabled semiconductor nanostructures, including silicon nanowires, carbon nanotubes, graphene. First, synthesis electrical of these are discussed context Second, affinity-based nano-bioelectronic sensors for highly sensitive analysis biomolecules reviewed. studies, nanostructures as transistor-based biosensors from device behavior through sensing applications future challenges. Third, complex interface between nanoelectronics living systems, single cells live animals, is discussion focuses on representative electrophysiology using nanoelectronic devices cellular measurements emerging work where arrays incorporated within three-dimensional cell networks define synthetic natural tissues. Last, some exciting discussed.

Language: Английский

Citations

579
Electrospinning for drug delivery applications: A review DOI Creative Commons
Andrea Luraghi, Francesco Peri, Lorenzo Moroni

et al.

Journal of Controlled Release, Journal Year: 2021, Volume and Issue: 334, P. 463 - 484

Published: March 27, 2021

Drug delivery devices are promising tools in the pharmaceutical field, as they able to maximize therapeutic effects of delivered drug while minimizing undesired side effects. In past years, electrospun nanofibers attracted rising attention due their unique features, like biocompatibility and broad flexibility. Incorporation active principles nanofibrous meshes proved be an efficient method for situ a wide range drugs, expanding possibility applicability those devices. this review, principle electrospinning different fields applications treated give overview recent literature, underlining easy tuning endless combination technique, that future could new frontier personalized medicine.

Language: Английский

Citations

555
Quadruple H-Bonding Cross-Linked Supramolecular Polymeric Materials as Substrates for Stretchable, Antitearing, and Self-Healable Thin Film Electrodes DOI
Xuzhou Yan, Zhiyuan Liu, Qiuhong Zhang

et al.

Journal of the American Chemical Society, Journal Year: 2018, Volume and Issue: 140(15), P. 5280 - 5289

Published: March 29, 2018

Herein, we report a de novo chemical design of supramolecular polymer materials (SPMs-1–3) by condensation polymerization, consisting (i) soft polymeric chains (polytetramethylene glycol and tetraethylene glycol) (ii) strong reversible quadruple H-bonding cross-linkers (from 0 to 30 mol %). The former contributes the formation domain SPMs, latter furnishes SPMs with desirable mechanical properties, thereby producing soft, stretchable, yet tough elastomers. resulting SPM-2 was observed be highly stretchable (up 17 000% strain), (fracture energy ∼30 000 J/m2), self-healing, which are properties superior previously reported elastomers hydrogels. Furthermore, gold, thin film electrode deposited on this SPM substrate retains its conductivity combines high stretchability (∼400%), fracture/notch insensitivity, good interfacial adhesion gold film. Again, these all complementary commonly used polydimethylsiloxane-based metal electrodes. Last, proceed demonstrate practical utility our fabricated via both in vivo vitro measurements electromyography signals. This fundamental understanding obtained from investigation will facilitate progress intelligent flexible electronics.

Language: Английский

Citations

554