An Integrated Brain-Machine Interface Platform With Thousands of Channels

Journal of Medical Internet Research, Journal Year: 2019, Volume and Issue: 21(10), P. e16194 - e16194

Published: Oct. 14, 2019

Brain-machine interfaces hold promise for the restoration of sensory and motor function treatment neurological disorders, but clinical brain-machine have not yet been widely adopted, in part, because modest channel counts limited their potential. In this white paper, we describe Neuralink's first steps toward a scalable high-bandwidth interface system. We built arrays small flexible electrode "threads," with as many 3072 electrodes per array distributed across 96 threads. also neurosurgical robot capable inserting six threads (192 electrodes) minute. Each thread can be individually inserted into brain micron precision avoidance surface vasculature targeting specific regions. The is packaged implantable device that contains custom chips low-power on-board amplification digitization: package channels occupies less than 23×18.5×2 mm

Language: Английский

---

Neuropixels 2.0: A miniaturized high-density probe for stable, long-term brain recordings

Science, Journal Year: 2021, Volume and Issue: 372(6539)

Published: April 15, 2021

Measuring the dynamics of neural processing across time scales requires following spiking thousands individual neurons over milliseconds and months. To address this need, we introduce Neuropixels 2.0 probe together with newly designed analysis algorithms. The has more than 5000 sites is miniaturized to facilitate chronic implants in small mammals recording during unrestrained behavior. High-quality recordings long were reliably obtained mice rats six laboratories. Improved site density arrangement combined created data methods enable automatic post hoc correction for brain movements, allowing from same 2 These probes algorithms stable free behavior, even animals such as mice.

Language: Английский

---

Hydrogel interfaces for merging humans and machines

Nature Reviews Materials, Journal Year: 2022, Volume and Issue: 7(12), P. 935 - 952

Published: Oct. 13, 2022

Language: Английский

---

A tissue-like neurotransmitter sensor for the brain and gut

Nature, Journal Year: 2022, Volume and Issue: 606(7912), P. 94 - 101

Published: June 1, 2022

Language: Английский

---

Functionalized helical fibre bundles of carbon nanotubes as electrochemical sensors for long-term in vivo monitoring of multiple disease biomarkers

Nature Biomedical Engineering, Journal Year: 2019, Volume and Issue: 4(2), P. 159 - 171

Published: Oct. 28, 2019

Language: Английский

---

Wireless and battery-free technologies for neuroengineering

Nature Biomedical Engineering, Journal Year: 2021, Volume and Issue: 7(4), P. 405 - 423

Published: March 8, 2021

Language: Английский

---

Large-scale neural recordings call for new insights to link brain and behavior

Nature Neuroscience, Journal Year: 2022, Volume and Issue: 25(1), P. 11 - 19

Published: Jan. 1, 2022

Language: Английский

---

Bioinspired bio-voltage memristors

Nature Communications, Journal Year: 2020, Volume and Issue: 11(1)

Published: April 20, 2020

Memristive devices are promising candidates to emulate biological computing. However, the typical switching voltages (0.2-2 V) in previously described much higher than amplitude counterparts. Here we demonstrate a type of diffusive memristor, fabricated from protein nanowires harvested bacterium Geobacter sulfurreducens, that functions at 40-100 mV. function is possible because catalyze metallization. Artificial neurons built these memristors not only action potentials (e.g., 100 mV, 1 ms) but also exhibit temporal integration close neurons. The potential using memristor directly process biosensing signals demonstrated.

Language: Английский

---

Functional Fiber Materials to Smart Fiber Devices

Chemical Reviews, Journal Year: 2022, Volume and Issue: 123(2), P. 613 - 662

Published: Aug. 17, 2022

The development of fiber materials has accompanied the evolution human civilization for centuries. Recent advances in science and chemistry offered fibers new applications with various functions, including energy harvesting, storing, displaying, health monitoring treating, computing. unique one-dimensional shape devices endows them advantages to work as human-interfaced electronics due small size, lightweight, flexibility, feasibility integration into large-scale textile systems. In this review, we first present a discussion basics design principles devices, followed by comprehensive analysis on recently developed devices. Finally, provide current challenges facing field give an outlook future research directions. With novel continuing be discovered after two decades research, envision that could have important impact our life near future.

Language: Английский

---

Integrative Benchmarking to Advance Neurally Mechanistic Models of Human Intelligence

Neuron, Journal Year: 2020, Volume and Issue: 108(3), P. 413 - 423

Published: Sept. 11, 2020

A potentially organizing goal of the brain and cognitive sciences is to accurately explain domains human intelligence as executable, neurally mechanistic models. Years research have led models that capture experimental results in individual behavioral tasks regions. We here advocate for taking next step: integrating from many laboratories into suites benchmarks that, when considered together, push toward explaining entire intelligence, such vision, language, motor control. Given recent successes surging availability neural, anatomical, data, we believe now time create integrative benchmarking platforms incentivize ambitious, unified This perspective discusses advantages challenges this approach proposes specific steps achieve domain visual with case study an platform called Brain-Score.

Language: Английский

---