American Journal of Clinical Nutrition, Journal Year: 2022, Volume and Issue: 116(6), P. 1877 - 1900
Published: Aug. 30, 2022
Language: Английский
CA A Cancer Journal for Clinicians, Journal Year: 2020, Volume and Issue: 70(4), P. 245 - 271
Published: June 9, 2020
Abstract The American Cancer Society (ACS) publishes the Diet and Physical Activity Guideline to serve as a foundation for its communication, policy, community strategies and, ultimately, affect dietary physical activity patterns among Americans. This guideline is developed by national panel of experts in cancer research, prevention, epidemiology, public health, reflects most current scientific evidence related risk. ACS focuses on recommendations individual choices regarding diet patterns, but those occur within context that either facilitates or creates barriers healthy behaviors. Therefore, this committee presents action accompany 4 reduce These recognize supportive social environment indispensable if individuals at all levels society are have genuine opportunities choose 2020 consistent with guidelines from Heart Association Diabetes prevention coronary heart disease diabetes well general health promotion, defined 2015 Dietary Guidelines Americans 2018
Language: Английский
Citations
603
CA A Cancer Journal for Clinicians, Journal Year: 2021, Volume and Issue: 71(4), P. 333 - 358
Published: May 13, 2021
Abstract Cancer has myriad effects on metabolism that include both rewiring of intracellular to enable cancer cells proliferate inappropriately and adapt the tumor microenvironment, changes in normal tissue metabolism. With recognition fluorodeoxyglucose‐positron emission tomography imaging is an important tool for management many cancers, other metabolites biological samples have been spotlight diagnosis, monitoring, therapy. Metabolomics global analysis small molecule like ‐omics technologies can provide critical information about state are otherwise not apparent. Here, authors review how therapies interact with at cellular systemic levels. An overview metabolomics provided a focus currently available they applied clinical translational research setting. The also discuss could be further leveraged future improve patients cancer.
Language: Английский
Citations
502
Nutrients, Journal Year: 2019, Volume and Issue: 11(9), P. 2059 - 2059
Published: Sept. 2, 2019
The Mediterranean diet is considered one of the most worldwide healthy dietary patterns thanks to a combination foods rich mainly in antioxidants and anti-inflammatory nutrients. Many studies have demonstrated strong inverse relationship between high level adherence some chronic diseases (such as cardiovascular diseases, diabetes, etc.) cancer. Given its protective effects reducing oxidative inflammatory processes cells avoiding DNA damages, cell proliferation, their survival, angiogenesis, inflammations metastasis, powerful manageable method fight cancer incidence. aim this narrative review was determine magnitude interaction more widespread types so give first useful overview on identifying, with nutritional approach, those nutrients able reduce
Language: Английский
Citations
404
Cell Metabolism, Journal Year: 2021, Volume and Issue: 33(8), P. 1701 - 1715.e5
Published: June 11, 2021
Language: Английский
Citations
333
Immunity, Journal Year: 2018, Volume and Issue: 49(2), P. 353 - 362.e5
Published: Aug. 1, 2018
The epithelium and immune compartment in the intestine are constantly exposed to a fluctuating external environment. Defective communication between these compartments at this barrier surface underlies susceptibility infections chronic inflammation. Environmental factors play significant, but mechanistically poorly understood, role intestinal homeostasis. We found that regeneration of epithelial cells (IECs) upon injury through infection or chemical insults was profoundly influenced by environmental sensor aryl hydrocarbon receptor (AHR). IEC-specific deletion Ahr resulted failure control C. rodentium due unrestricted stem cell (ISC) proliferation impaired differentiation, culminating malignant transformation. AHR activation dietary ligands restored homeostasis, protected niche, prevented tumorigenesis via transcriptional regulation Rnf43 Znrf3, E3 ubiquitin ligases inhibit Wnt-β-catenin signaling restrict ISC proliferation. Thus, pathway IECs guards niche maintain integrity.
Language: Английский
Citations
329
Frontiers in Plant Science, Journal Year: 2017, Volume and Issue: 8
Published: May 23, 2017
Many plants, including some of the commonly consumed herbs and spices in our daily food, can be safely effectively used to prevent and/or treat health concerns. For example, caffeine active ingredient found coffee beans (Coffea), shows biological activity treatment central nervous system (CNS) disorders, indole-3-carbinol, 3,3'-diindolylmethane are both broccoli (Brassica oleracea) derived phytochemicals with potential anti-cancer activity, resveratrol, isolated from grape (Vitis vinifera), is reported extend lifespan provide cardio-neuro-protective, anti-diabetic, effects. Date palm fruits possess high nutritional therapeutic value significant antioxidant, antibacterial, antifungal, anti-proliferative properties. This review focuses on date fruit extracts their benefits individual promoting conditions highlights applications as useful pharmaceutical nutraceutical industries development natural compound-based industrial products.
Language: Английский
Citations
286
Nature Reviews Gastroenterology & Hepatology, Journal Year: 2021, Volume and Issue: 18(8), P. 559 - 570
Published: March 19, 2021
Language: Английский
Citations
260
Nature Communications, Journal Year: 2021, Volume and Issue: 12(1)
Published: July 28, 2021
There is evidence that diet and nutrition are modifiable risk factors for several cancers, but associations may be flawed due to inherent biases. Nutritional epidemiology studies have largely relied on a single assessment of using food frequency questionnaires. We conduct an umbrella review meta-analyses observational evaluate the strength validity association between food/nutrient intake developing or dying from 11 primary cancers. It estimated only few cancer supported by strong highly suggestive meta-analytic evidence, future similar research unlikely change this evidence. Alcohol consumption positively associated with postmenopausal breast, colorectal, esophageal, head & neck liver cancer. Consumption dairy products, milk, calcium wholegrains inversely colorectal risk. Coffee skin basal cell carcinoma.
Language: Английский
Citations
163
Cancer Cell, Journal Year: 2020, Volume and Issue: 37(6), P. 767 - 785
Published: May 14, 2020
Language: Английский
Citations
158
Nutrition & Metabolism, Journal Year: 2021, Volume and Issue: 18(1)
Published: Jan. 7, 2021
In order to recapitulate the best available evidence of milk consumption and multiple health-related outcomes, we performed an umbrella review meta-analyses systematic reviews in humans. Totally, 41 with 45 unique health outcomes were included. Milk was more often related benefits than harm a sequence outcomes. Dose-response analyses indicated that increment 200 ml (approximately 1 cup) intake per day associated lower risk cardiovascular disease, stroke, hypertension, colorectal cancer, metabolic syndrome, obesity osteoporosis. Beneficial associations also found for type 2 diabetes mellitus Alzheimer's disease. Conversely, might be higher prostate Parkinson's acne Fe-deficiency anaemia infancy. Potential allergy or lactose intolerance need caution. does good human this review. Our results support as part healthy diet. More well-designed randomized controlled trials are warranted.
Language: Английский
Citations
131