Cooperation in microbial communities and their biotechnological applications DOI Creative Commons
Matteo Cavaliere, Song Feng, Orkun S. Soyer

et al.

Environmental Microbiology, Journal Year: 2017, Volume and Issue: 19(8), P. 2949 - 2963

Published: April 27, 2017

Summary Microbial communities are increasingly utilized in biotechnology. Efficiency and productivity many of these applications depends on the presence cooperative interactions between members community. Two key processes underlying production public goods metabolic cross‐feeding, which can be understood general framework ecological evolutionary (eco‐evo) dynamics. In this review, we illustrate relevance microbial biotechnological processes, discuss their mechanistic origins analyse resilience. Cooperative behaviours damaged by emergence ‘cheating’ cells that benefit from but do not contribute to them. Despite this, stabilized spatial segregation, feedbacks dynamics ecology community, role regulatory systems coupled environmental conditions action horizontal gene transfer. enrich with a higher degree robustness against stress facilitate evolution more complex traits. Therefore, resilience ability constraint detrimental mutants should considered design robust applications.

Language: Английский

The Peculiar Functions of the Bacterial Extracellular Matrix DOI
Anna Dragoš, Ákos T. Kovács

Trends in Microbiology, Journal Year: 2017, Volume and Issue: 25(4), P. 257 - 266

Published: Jan. 11, 2017

Language: Английский

Citations

210
Recent developments in smart antibacterial surfaces to inhibit biofilm formation and bacterial infections DOI

Xi Li,

Biao Wu, Hao Chen

et al.

Journal of Materials Chemistry B, Journal Year: 2018, Volume and Issue: 6(26), P. 4274 - 4292

Published: Jan. 1, 2018

Since their development over 70 years, antibiotics are still the most effective strategy to treat bacterial biofilms and infections.

Language: Английский

Citations

210
Spatial transcriptomics of planktonic and sessile bacterial populations at single-cell resolution DOI
Daniel Dar,

Nina Dar,

Long Cai

et al.

Science, Journal Year: 2021, Volume and Issue: 373(6556)

Published: Aug. 12, 2021

Capturing the heterogeneous phenotypes of microbial populations at relevant spatiotemporal scales is highly challenging. Here, we present par-seqFISH (parallel sequential fluorescence in situ hybridization), a transcriptome-imaging approach that records gene expression and spatial context within microscale assemblies single-cell molecule resolution. We applied this to opportunistic pathogen Pseudomonas aeruginosa, analyzing about 600,000 individuals across dozens conditions planktonic biofilm cultures. identified numerous metabolic- virulence-related transcriptional states emerged dynamically during growth, as well spatially resolved metabolic heterogeneity sessile populations. Our data reveal distinct physiological can coexist same just several micrometers away, underscoring importance microenvironment. results illustrate complex dynamics new way studying them high

Language: Английский

Citations

209
Gastrointestinal biofilms in health and disease DOI
Jean‐Paul Motta, John L. Wallace, André G. Buret

et al.

Nature Reviews Gastroenterology & Hepatology, Journal Year: 2021, Volume and Issue: 18(5), P. 314 - 334

Published: Jan. 28, 2021

Language: Английский

Citations

204
Cooperation in microbial communities and their biotechnological applications DOI Creative Commons
Matteo Cavaliere, Song Feng, Orkun S. Soyer

et al.

Environmental Microbiology, Journal Year: 2017, Volume and Issue: 19(8), P. 2949 - 2963

Published: April 27, 2017

Summary Microbial communities are increasingly utilized in biotechnology. Efficiency and productivity many of these applications depends on the presence cooperative interactions between members community. Two key processes underlying production public goods metabolic cross‐feeding, which can be understood general framework ecological evolutionary (eco‐evo) dynamics. In this review, we illustrate relevance microbial biotechnological processes, discuss their mechanistic origins analyse resilience. Cooperative behaviours damaged by emergence ‘cheating’ cells that benefit from but do not contribute to them. Despite this, stabilized spatial segregation, feedbacks dynamics ecology community, role regulatory systems coupled environmental conditions action horizontal gene transfer. enrich with a higher degree robustness against stress facilitate evolution more complex traits. Therefore, resilience ability constraint detrimental mutants should considered design robust applications.

Language: Английский

Citations

187