Exercise Training Improves HR Responses and V˙O2peak in Predialysis Kidney Patients DOI Open Access
Samuel Headley, Michael J. Germain,

Charles Milch

et al.

Medicine & Science in Sports & Exercise, Journal Year: 2012, Volume and Issue: 44(12), P. 2392 - 2399

Published: Dec. 1, 2012

The current pilot and feasibility study was designed to examine the effect of 48 wk moderate-intensity exercise training dietary modification on kidney function vascular parameters in chronic disease (CKD) patients.Twenty-one stage 2-4 CKD patients (age, 18-70 yr) were randomly assigned either group (TG, n = 10) or usual care (n 11) for wk. TG received personal (3 d·wk up 55 min per session at 50%-60% V˙O2peak) counseling, whereas individuals standard instructed not start a structured program while study. V˙O2peak, estimated glomerular filtration rate (eGFR), resting ambulatory HR, plasma lipids (total cholesterol, LDL HDL triglycerides), inflammatory markers (high-sensitivity C-reactive protein interleukin 6) assessed baseline weeks 24 48. An independent group's t-test used compare slopes between groups, all other data analyzed with ANCOVA using value as covariate.There no statistically significant differences any baseline. 48-wk intervention led increase reductions both increases cholesterol TG, but it had change eGFR over time.A program, primarily focused aerobic exercise, V˙O2peak favorably alters autonomic evidenced by HR stages patients. eGFR.

Language: Английский

A Prospective Controlled Study of Kidney Donors: Baseline and 6-Month Follow-up DOI
Bertram L. Kasiske, Teresa L. Anderson-Haag, Hassan N. Ibrahim

et al.

American Journal of Kidney Diseases, Journal Year: 2013, Volume and Issue: 62(3), P. 577 - 586

Published: March 22, 2013

Language: Английский

Citations

75
SARS‐CoV‐2 induced HDL dysfunction may affect the host's response to and recovery from COVID‐19 DOI Creative Commons
Hayder M. Al‐kuraishy,

Nawar Raad Hussien,

Marwa S. Al‐Niemi

et al.

Immunity Inflammation and Disease, Journal Year: 2023, Volume and Issue: 11(5)

Published: May 1, 2023

Covid-19 is linked with the development of cardio-metabolic disorders, including dyslipidemia, dysregulation high-density lipoprotein (HDL), and low-density (LDL). Furthermore, SARS-Co-2 infection associated noteworthy changes in lipid profile, which suggested as a possible biomarker to support diagnosis management Covid-19.

Language: Английский

Citations

20
The association between monocyte to high-density lipoprotein cholesterol ratio and chronic kidney disease in a Chinese adult population: a cross-sectional study DOI Creative Commons
Lingling Xu,

Dongling Li,

Zongwei Song

et al.

Renal Failure, Journal Year: 2024, Volume and Issue: 46(1)

Published: March 24, 2024

Background Monocyte to high-density lipoprotein cholesterol ratio (MHR) was confirmed as a novel inflammatory marker and strongly associated with the risk of several diseases. This study aimed investigate relationship between MHR chronic kidney disease (CKD) in Chinese adult population.

Language: Английский

Citations

6
Diminished Antioxidant Activity of High-Density Lipoprotein-Associated Proteins in Chronic Kidney Disease DOI
David J. Kennedy, W.H. Wilson Tang, Yiying Fan

et al.

Journal of the American Heart Association, Journal Year: 2013, Volume and Issue: 2(2), P. e000104 - e000104

Published: April 4, 2013

Background--Decreased serum arylesterase activity, catalyzed by the high-density lipoprotein-associated paraoxonase (PON)-1, is associated with increased oxidant stress and atherosclerosis risk.We sought to determine prognostic value of PON-1 as monitored PON or activities, in subjects chronic kidney disease (CKD), particularly relation established cardiac biomarkers.Methods Results--Serum activities were measured sequential CKD (n=630; estimated glomerular filtration rate [eGFR] <60 mL/min per 1.73 m 2 ) an age-and sex-matched control group non-CKD (n=315) presenting for evaluations prospectively followed incident (3-year) major adverse events (composite death, nonfatal myocardial infarction, stroke).Serum activity was lower compared that [median (interquartile range) 94 (77 112) versus 103 (85 121) lmol(LÁmin) mL, P<0.001]; similarly, 474 (275 936) 586 (301 1118) nmol(LÁmin) P<0.001].Lower (hazard ratio 1.8, 95% CI 1.26 2.57, P<0.01) a predictor poorer outcomes.After adjusting traditional risk factors medication use, 1.55, 1.08 2.23, P<0.05) still conferred at 3 years.Conclusions--In patients CKD, decreased measure diminished antioxidant properties PON-1, predicts higher long-term cardiovascular (heart attack, stroke, death) multivariable models clinical biochemical factors.(

Language: Английский

Citations

70
Exercise Training Improves HR Responses and V˙O2peak in Predialysis Kidney Patients DOI Open Access
Samuel Headley, Michael J. Germain,

Charles Milch

et al.

Medicine & Science in Sports & Exercise, Journal Year: 2012, Volume and Issue: 44(12), P. 2392 - 2399

Published: Dec. 1, 2012

The current pilot and feasibility study was designed to examine the effect of 48 wk moderate-intensity exercise training dietary modification on kidney function vascular parameters in chronic disease (CKD) patients.Twenty-one stage 2-4 CKD patients (age, 18-70 yr) were randomly assigned either group (TG, n = 10) or usual care (n 11) for wk. TG received personal (3 d·wk up 55 min per session at 50%-60% V˙O2peak) counseling, whereas individuals standard instructed not start a structured program while study. V˙O2peak, estimated glomerular filtration rate (eGFR), resting ambulatory HR, plasma lipids (total cholesterol, LDL HDL triglycerides), inflammatory markers (high-sensitivity C-reactive protein interleukin 6) assessed baseline weeks 24 48. An independent group's t-test used compare slopes between groups, all other data analyzed with ANCOVA using value as covariate.There no statistically significant differences any baseline. 48-wk intervention led increase reductions both increases cholesterol TG, but it had change eGFR over time.A program, primarily focused aerobic exercise, V˙O2peak favorably alters autonomic evidenced by HR stages patients. eGFR.

Language: Английский

Citations

68