Consensus Parameter: Research Methodologies to Evaluate Neurodevelopmental Effects of Pubertal Suppression in Transgender Youth DOI Creative Commons
Diane Chen, John F. Strang, Victoria D. Kolbuck

et al.

Transgender Health, Journal Year: 2020, Volume and Issue: 5(4), P. 246 - 257

Published: June 9, 2020

Purpose: Pubertal suppression is standard of care for early pubertal transgender youth to prevent the development undesired and distressing secondary sex characteristics incongruent with gender identity. Preliminary evidence suggests improves mental health functioning. Given widespread changes in brain cognition that occur during puberty, a critical question whether this treatment impacts neurodevelopment. Methods: A Delphi consensus procedure engaged 24 international experts neurodevelopment, development, puberty/adolescence, neuroendocrinology, statistics/psychometrics identify priority research methodologies address empirical question: associated real-world neurocognitive sequelae? Recommended study approaches reaching 80% were included parameter. Results: The identified 160 initial expert recommendations, 44 which ultimately achieved consensus. Consensus design elements include following: minimum three measurement time points, staging at baseline, statistical modeling analyses, use analytic account heterogeneity, multiple comparison groups minimize limitations any one group. untreated matched on stage, cisgender (i.e., congruent) an independent sample from large-scale database. domains assessment includes: health, executive function/cognitive control, social awareness/functioning. Conclusion: An interdisciplinary team around primary methods assessing neurodevelopmental effects benefits and/or difficulties) youth.

Language: Английский

Neuromarketing algorithms’ consumer privacy and ethical considerations: challenges and opportunities DOI Creative Commons
Marcus Gonçalves, Yiwei Hu, Irene Aliagas

et al.

Cogent Business & Management, Journal Year: 2024, Volume and Issue: 11(1)

Published: April 4, 2024

This research investigates the ethical and privacy issues arising from using AI andML in neuromarketing, framed by rule utilitarianism. It assesses impact of these technologies on consumerprivacy human rights through a combination literature review, bibliometric analysis, empirical data fromsurveys interviews with experts US Spain. The study reveals tensions between efficacy ofneuromarketing techniques imperative to protect consumer privacy, particularly light GDPR'sinfluence global practices. emphasizes need for internationally consistent standards consumerdata regulations, drawing comparative analysis policies EU. outcomes include policyrecommendations minimize risks promote responsible progression neuromarketing. Theserecommendations guide companies managers toward transparency accountability. Additionally, theresearch offers policy framework crafting neuromarketing practices that reconcile technological progresswith well-being, thereby contributing broader discussions embedding ethics within innovation.

Language: Английский

Citations

12

Developing, Testing, and Communicating Earthquake Forecasts: Current Practices and Future Directions DOI Creative Commons
Leila Mizrahi, Irina Dallo, N. van der Elst

et al.

Reviews of Geophysics, Journal Year: 2024, Volume and Issue: 62(3)

Published: Aug. 13, 2024

Abstract While deterministically predicting the time and location of earthquakes remains impossible, earthquake forecasting models can provide estimates probabilities occurring within some region over time. To enable informed decision‐making civil protection, governmental agencies, or public, Operational Earthquake Forecasting (OEF) systems aim to authoritative forecasts based on current activity in near‐real Establishing OEF involves several nontrivial choices. This review captures state worldwide analyzes expert recommendations development, testing, communication forecasts. An introductory summary OEF‐related research is followed by a description Italy, New Zealand, United States. Combined, these two parts an informative transparent snapshot today's landscape. In Section 4, we analyze results elicitation that was conducted seek guidance for establishment systems. The identifies consensus dissent issues among non‐representative group 20 international experts. experts agree products should be developed collaboration with forecast user groups, they disagree whether testing methods user‐dependent. No strict model requirements could elicited, but benchmark comparisons, prospective reproducibility, transparency are encouraged. 5 gives outlook future OEF. Besides covering recent development upcoming initiatives described context findings.

Language: Английский

Citations

11

ACcurate COnsensus Reporting Document (ACCORD) explanation and elaboration: Guidance and examples to support reporting consensus methods DOI Creative Commons
Patrícia Logullo, Esther J van Zuuren, Christopher Winchester

et al.

PLoS Medicine, Journal Year: 2024, Volume and Issue: 21(5), P. e1004390 - e1004390

Published: May 6, 2024

When research evidence is limited, inconsistent, or absent, healthcare decisions and policies need to be based on consensus amongst interested stakeholders. In these processes, the knowledge, experience, expertise of health professionals, researchers, policymakers, public are systematically collected synthesised reach agreed clinical recommendations and/or priorities. However, despite influence exercises, methods used achieve agreement often poorly reported. The ACCORD (ACcurate COnsensus Reporting Document) guideline was developed help report any in biomedical research, regardless field, techniques used, application. This explanatory document facilitates use checklist.

Language: Английский

Citations

8

Sample size in multistakeholder Delphi surveys: at what minimum sample size do replicability of results stabilize? DOI Creative Commons
Anthony Muchai Manyara,

Anthony Purvis,

Oriana Ciani

et al.

Journal of Clinical Epidemiology, Journal Year: 2024, Volume and Issue: 174, P. 111485 - 111485

Published: July 26, 2024

Background and ObjectiveThe minimum sample size for multistakeholder Delphi surveys remains understudied. Drawing from three large international surveys, this study aimed to: 1) investigate the effect of increasing on replicability results; 2) assess whether level results differed with participant characteristics: example, gender, age, profession.MethodsWe used data to develop guidance improved reporting health-care intervention trials: SPIRIT (Standard Protocol Items: Recommendations Interventional Trials) CONSORT (Consolidated Standards Reporting extension surrogate end points (n = 175, 22 items rated); CONSORT-SPI [CONSORT Social Psychological Interventions] 333, 77 core outcome set burn care 553, 88 rated). Resampling replacement was draw random subsamples in each surveys. For subsample, median value all rated survey calculated compared medians full set. The number (and interquartile range) replicated calculate percentage variability). High defined as ≥80% moderate 60% <80%ResultsThe average (variability) a total datasets 81% (10%) at 60. In one (CONSORT-SPI), reached 80. On average, 80 160 increased by further 3% reduced variability 1%. subgroup analysis based characteristics (eg, professional role), using resampled samples 20 100 showed that 30 resulted levels 64% 77%.ConclusionWe found 60–80 participants provides high (≥80%) results. studies limited individual stakeholder groups (such researchers, clinicians, patients), per group may be sufficient.

Language: Английский

Citations

8

Building Consensus on the Relevant Criteria to Screen for Depressive Symptoms Among Near-Centenarians and Centenarians: Modified e-Delphi Study DOI Creative Commons
Carla Gomes da Rocha, Armin von Gunten, Pierre Vandel

et al.

JMIR Aging, Journal Year: 2025, Volume and Issue: 8, P. e64352 - e64352

Published: March 5, 2025

The number of centenarians worldwide is expected to increase dramatically, reaching 3.4 million by 2050 and >25 2100. Despite these projections, depression remains a prevalent yet underdiagnosed undertreated condition among this population that carries significant health risks. This study aimed identify achieve consensus on the most representative signs symptoms in near-centenarians (aged ≥95 years) through an e-Delphi with international interdisciplinary panel experts. Ultimately, outcomes might help create screening instrument specifically designed for unique population. A modified was carried out expert depressive centenarians. 28 experts recruited. Consensus defined as 70% agreement relevance each item. Data were collected web-based questionnaire over 3 rounds. Experts rated 104 items divided into 24 dimensions 80 criteria age group. consisted from various countries, including physicians experience old psychiatry or geriatrics well nurses psychologists. response rate remained consistent rounds (20/28, 71% 21/28, 75%). In total, 4 new 8 proposed experts, reached 86% (24/28) 80% (70/88) criteria. consensual potentially relevant lack hope (21/21, 100%), loss interest (27/28, 96%), reactivity pleasant events depressed mood (26/28, 93%), previous episodes diagnosed (19/21, 90%). addition, despondency, gloom, despair (25/25, 100%); (27/27, circumstances (28/28, suicidal ideation suicide attempt(s) ruminations 96%); recurrent thoughts death feelings worthlessness (25/26, critical life (20/21, 95%); anhedonia activities 93%); pleasure sadness (24/26, 92%). Moreover, when assessing very age, duration, number, frequency, severity should also be considered, evidenced high agreement. classification elements highlights importance multidimensional approach optimal individuals age. offers first step toward improving assessment development more adapted tool could improve early detection intervention, enhancing quality mental care

Language: Английский

Citations

1

Consensus based framework for digital mobility monitoring DOI Creative Commons
Felix Kluge, Silvia Del Din, Andrea Cereatti

et al.

PLoS ONE, Journal Year: 2021, Volume and Issue: 16(8), P. e0256541 - e0256541

Published: Aug. 20, 2021

Digital mobility assessment using wearable sensor systems has the potential to capture walking performance in a patient’s natural environment. It enables monitoring of health status and disease progression evaluation interventions real-world situations. In contrast laboratory settings, occurs non-conventional environments under unconstrained uncontrolled conditions. Despite general understanding, there is lack agreed definitions about what constitutes walking, impeding comparison interpretation acquired data across studies. The goal this study was obtain expert-based consensus on specific aspects provide respective common terminological framework. An adapted Delphi method used related walking. an online survey, 162 participants from panel academic, clinical industrial experts with experience field gait analysis were asked for agreement previously specified definitions. Descriptive statistics evaluate whether consent (> 75% as defined priori) reached. Of invited participate, 51 completed all rounds (31.5% response rate). We obtained (“Walking” > 90%, “Purposeful” 75%, “Real-world” “Walking bout” 80%, speed” “Turning” 90% agreement) after two rounds. identification consented set important implications development protocols, well reporting digital outcomes studies systems. will serve framework implementing mobile technologies are link transition supervised unsupervised assessment.

Language: Английский

Citations

44

A scoping review of outdoor food marketing: exposure, power and impacts on eating behaviour and health DOI Creative Commons
Amy Finlay, Eric Robinson, Andrew Jones

et al.

BMC Public Health, Journal Year: 2022, Volume and Issue: 22(1)

Published: July 27, 2022

There is convincing evidence that unhealthy food marketing extensive on television and in digital media, uses powerful persuasive techniques, impacts dietary choices consumption, particularly children. It less clear whether this also the case for outdoor marketing. This review (i) identifies common criteria used to define marketing, (ii) summarises research methodologies used, (iii) available exposure, power (i.e. creative strategies within marketing) impact of behaviour health (iv) knowledge gaps directions future research.

Language: Английский

Citations

34

A research agenda for evaluating living labs as an open innovation model for environmental and agricultural sustainability DOI Creative Commons
Christine Beaudoin,

Steve Joncoux,

Jean-François Jasmin

et al.

Environmental Challenges, Journal Year: 2022, Volume and Issue: 7, P. 100505 - 100505

Published: March 29, 2022

The magnitude of environmental challenges we are facing today requires the involvement a diversity stakeholders and collaborators to develop socially, culturally, economically robust sustainability practices. Living labs catalyse development user-centric solutions for complex issues by exploring, co-creating, testing, evaluating innovations within real-world contexts. living lab approach is relatively new in agricultural sectors but quite well established many areas such as information communication technology. For play greater role sustainability, present research agenda related evaluation effectiveness context sustainability. We refer act assessing process outcomes lab, level which successful achieving certain desirable or outcome. Our based on empirical using an adapted Delphi method – iteratively gather input from panel experts involving total 44 researchers domains labs, methods, agro-environmental issues. resulting integrated identifies important gaps both practice improve impact labs. findings highlight need better understand effective use this collaborative, open innovation management focused Future should investigate knowledge have identified terms stakeholders, key dimensions how enable

Language: Английский

Citations

30

Personalized Management of Patients with Chronic Rhinosinusitis with Nasal Polyps in Clinical Practice: A Multidisciplinary Consensus Statement DOI Open Access
Eugenio De Corso, Maria Beatrice Bilò, Andrea Matucci

et al.

Journal of Personalized Medicine, Journal Year: 2022, Volume and Issue: 12(5), P. 846 - 846

Published: May 23, 2022

Chronic rhinosinusitis (CRS) is a sino-nasal chronic inflammatory disease, occurring in 5–15% of the general population. CRS with nasal polyps (CRSwNP) present up to 30% One-third CRSwNP patients suffer from disease that uncontrolled by current standards care. Biologics are an emerging treatment option for severe CRSwNP, but their positioning algorithm under discussion. Effective endotyping who could benefit biologics required, as suggested international guidelines. Other issues affecting management include comorbidities, such allergy, non-steroidal anti-inflammatory drug–exacerbated respiratory and asthma. Therefore, choice depends on many factors. A multidisciplinary approach may improve currently there no shared model. We summarize outcomes Delphi process involving panel otolaryngologists, pulmonologists, allergist-immunologists involved attempted reach consensus key statements relating diagnosis, endotyping, classification (including place biologics) patients.

Language: Английский

Citations

30

Early Detection and Prognostic Assessment of Cutaneous Melanoma DOI
Mohammed Kashani‐Sabet, Sancy A. Leachman, Jennifer Stein

et al.

JAMA Dermatology, Journal Year: 2023, Volume and Issue: 159(5), P. 545 - 545

Published: March 15, 2023

Therapy for advanced melanoma has transformed during the past decade, but early detection and prognostic assessment of cutaneous (CM) remain paramount goals. Best practices screening use pigmented lesion evaluation tools gene expression profile (GEP) testing in CM to be defined.

Language: Английский

Citations

21