Anti-obesity Medications for Monogenic Syndromic Obesity DOI

Shilpa Chugh Garcha,

Sanjay Kalra

Published: Jan. 1, 2025

Language: Английский

Obesity in children and adolescents: epidemiology, causes, assessment, and management DOI
Hiba Jebeile, Aaron S. Kelly, Grace O’Malley

et al.

The Lancet Diabetes & Endocrinology, Journal Year: 2022, Volume and Issue: 10(5), P. 351 - 365

Published: March 3, 2022

Language: Английский

Citations

585

Obesity and weight change during the COVID‐19 pandemic in children and adults: A systematic review and meta‐analysis DOI Creative Commons
Laura N. Anderson, Yulika Yoshida‐Montezuma,

Nora Dewart

et al.

Obesity Reviews, Journal Year: 2023, Volume and Issue: 24(5)

Published: Jan. 31, 2023

Summary Many obesity risk factors have increased during the COVID‐19 pandemic, including physical inactivity, poor diet, stress, and poverty. The aim of this systematic review was to evaluate impact as well associated lockdowns or restrictions, on weight change in children adults. We searched five databases from January 2020 November 2021. included only longitudinal studies with measures before pandemic that evaluated weight, body mass index (BMI) (or BMI z ‐scores for children), waist circumference, prevalence obesity. Random effects meta‐analyses were conducted obtain pooled estimates mean difference outcomes. Subgroups age groups diabetes at baseline. bias assessed using a modified version Newcastle‐Ottawa Scale, certainty evidence Grading Recommendations, Assessment, Development Evaluation (GRADE) approach. A total 74 (3,213,776 participants): 31 children, 41 adults, 2 In 1.65 kg (95% confidence interval [CI]: 0.40, 2.90; 9 studies) 0.13 CI 0.10, 0.17; 20 ‐scores, by 2% 1%, 3%; 12 studies). 0.93 0.54, 1.33; 27 0.38 kg/m 0.21, 0.55; 25 BMI, 1% 0%, 11 circumference 1.03 cm −0.08, 2.15; 4 There considerable heterogeneity observed all outcomes both GRADE very low During first year small but potentially clinically significant increases gain, adults observed. Increases greater targeted prevention interventions may be warranted.

Language: Английский

Citations

88

The promise of new anti-obesity therapies arising from knowledge of genetic obesity traits DOI Open Access
Anke Hinney, Antje Körner, Pamela Fischer‐Posovszky

et al.

Nature Reviews Endocrinology, Journal Year: 2022, Volume and Issue: 18(10), P. 623 - 637

Published: July 28, 2022

Language: Английский

Citations

77

European Society of Cardiology: the 2023 Atlas of Cardiovascular Disease Statistics DOI Creative Commons
Adam Timmis, Victor Aboyans, Panos E. Vardas

et al.

European Heart Journal, Journal Year: 2024, Volume and Issue: 45(38), P. 4019 - 4062

Published: Aug. 27, 2024

Abstract This report from the European Society of Cardiology (ESC) Atlas Project updates and expands upon 2021 in presenting cardiovascular disease (CVD) statistics for ESC member countries. paper examines inequalities healthcare outcomes countries utilizing mortality risk factor data World Health Organization Global Burden Disease study with additional economic Bank. Cardiovascular were collected by questionnaire circulated to national cardiac societies Statistics pertaining 2022, or latest available year, are presented. New material this includes contemporary estimates burden CVD a range phenotypes. accounts 11% EU’s total expenditure. It remains most common cause death over 3 million deaths per year. Proportionately more occur middle-income compared high-income both females (53% vs. 34%) males (46% 30%). Between 1990 2021, median age-standardized rates (ASMRs) decreased >50% but decrease was <12%. These between middle- likely reflect heterogeneous exposures environmental, socioeconomic, clinical factors. The 2023 survey suggests that treatment factors may also contribute reporting lower percutaneous coronary intervention (1355 2330), transcatheter aortic valve implantation (4.0 153.4) pacemaker (147.0 831.9) shows continuing epidemiology management exemplified changes ASMRs during last 30 years. In countries, have been steep decline period declines very small. There is now an important need targeted action reduce CVD, particularly those where greatest.

Language: Английский

Citations

43

Mental health in children and adolescents with overweight or obesity DOI Creative Commons

Lucas-Johann Förster,

Mandy Vogel, Robert Stein

et al.

BMC Public Health, Journal Year: 2023, Volume and Issue: 23(1)

Published: Jan. 19, 2023

Abstract Background Overweight and obesity represent huge concerns for children's physical mental well-being. This study examined the relationship between body mass index (BMI) health-related quality of life (HRQoL), somatoform complaints, behavioral problems in children adolescents. Additionally, influence sex, age, socioeconomic status (SES) on these associations was considered. Methods In total, we studied 2350 participants ages 4 18 years (1213 4- to 10-years-old (child sample) 1137 11-to 18-year-olds (adolescent sample)). To assess HRQoL, difficulties, applied KIDSCREEN-27, a short form Giessen Complaints Questionnaire, Strengths Difficulties Questionnaire (SDQ). The BMI transformed standard deviation scores (BMI-SDS), according German gender- age-specific reference data. Associations were investigated using linear regression analyses. Each association checked interaction with SES. Results Regarding found worsening well-being psychological increasing BMI-SDS. Somatoform complaints not significantly associated Conduct problems, peer emotional (the latter only adolescent positively While did observe any significant interactions some age and/or Conclusion Our findings highlight importance difficulties adolescents higher and, consequently, underline relevance including interventions treatment overweight or obesity.

Language: Английский

Citations

42

Obesity and COVID-19 in Children and Adolescents: Reciprocal Detrimental Influence—Systematic Literature Review and Meta-Analysis DOI Open Access
Giusy La Fauci, Marco Montalti, Zeno Di Valerio

et al.

International Journal of Environmental Research and Public Health, Journal Year: 2022, Volume and Issue: 19(13), P. 7603 - 7603

Published: June 21, 2022

The dramatic lifestyle changes forced by COVID-19-related lockdown promoted weight gain, with a stronger impact on obese subjects, at higher risk of severe infection. PubMed database was searched to identify original studies assessing: (1) the extent and factors lockdown-induced increase; (2) obesity hospital admission in children adolescents. A systematic literature review meta-analyses were performed. Twenty out 13,986 identified records included. significant increase reported majority no apparent gender or age differences. It induced consumption hypercaloric/hyperglycemic/junk food and/or reduction physical activity, often associated an altered sleep-wake cycle. On other hand, increased hospitalization (OR = 4.38; 95% C.I. 1.46-13.19; p 0.009; I2 96%) as compared normal population. COVID-19 represent epidemic conditions reciprocal detrimental impact. Urgent public health interventions, targeting various social strata, involving governmental authorities, care personnel, teachers families are warranted awareness actively promote healthy lifestyles contrast pediatric its consequences global level.

Language: Английский

Citations

51

Associations of behavioral, motivational, and socioeconomic factors with BMI among children and adolescents DOI Creative Commons

Charlotte Jungehuelsing,

Christof Meigen,

Sarah Krause

et al.

Pediatric Research, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 17, 2025

Higher weight represents a significant health concern in youth and may be influenced by socioeconomic behavioral factors. We investigated the relationship between BMI parental education, nutritional health, eating culture, organized non-organized physical activity (PA), motives for PA (weight loss/maintenance, enjoyment), screen-time children adolescents. 677 2- to 11-year-olds (young-age-group) 464 12- 20-year-olds (old-age-group) from Leipzig, city Germany, participated. applied multivariate linear regression analyses assess associations. BMI-SDS was negatively associated with education (young-age-group: b = -0.25, p < 0.001, old-age-group: -0.27, 0.02), -0.23, 0.029), enjoyment -0.05, 0.01, 0.038), but media use during dinner (old-age-group: 0.53, 0.001), loss/maintenance 0.15, 0.12, 0.11, 0.009, 0.09, 0.001). Significant interactions age, sex were observed. A lower is high screen-free eating, higher participation screen-time. While measures of motivation limited thus findings should interpreted caution, intrinsic whereas extrinsic BMI. In German cohort adolescents, less screen time, more dinner. Intrinsic are directly linked status These associations particularly strong families low/medium formal education.

Language: Английский

Citations

1

Comparison of Physical Fitness Profiles Obtained before and during COVID-19 Pandemic in Two Independent Large Samples of Children and Adolescents: DAFIS Project DOI Open Access
María Ruá-Alonso, Jéssica Rial-Vázquez, Iván Nine

et al.

International Journal of Environmental Research and Public Health, Journal Year: 2022, Volume and Issue: 19(7), P. 3963 - 3963

Published: March 26, 2022

COVID-19 pandemic restrictions might have negatively affected the health-related physical fitness of children and adolescents. The aim this study was to contrast body composition data two independent samples adolescents obtained from an online database (DAFIS project) before (n = 15,287) during 2101) first academic year pandemic. results revealed higher values for mass index (p 0.002), waist circumference < 0.001), hip height ratios 0.001) than pandemic, particularly in case boys. On other hand, lower muscular observed girls Quantitative qualitative analysis did not detect relevant changes cardiorespiratory or > 0.05). Our suggested that constraints These be interest designing specific interventions oriented toward counteracting negative effects on fitness.

Language: Английский

Citations

29

Changes in Lifestyle and Body Weight in Children and Adolescents during the COVID-19 Pandemic: A Representative Survey of Parents in Germany DOI Creative Commons
Susann Blüher,

Oliver Huizinga,

Christine Joisten

et al.

Obesity Facts, Journal Year: 2023, Volume and Issue: 16(3), P. 301 - 312

Published: Jan. 1, 2023

The public restrictions taken during the COVID-19 pandemic have substantially affected lifestyle and health behavior of children adolescents. In Germany, little is known how these changes influenced daily life in families with adolescents.A cross-sectional survey was performed April/May 2022 across similar to a 2020. Parents (N = 1,004, 20-65 years) at least one child aged 3-17 years filled an online questionnaire released by Forsa Institute for Social Research Statistical Analysis. Fifteen questions related eating habits, dietary patterns, physical activity, media consumption, fitness, mental health, body weight were included, standard socioeconomic parameters assessed.Parents' answers indicated that there parental self-reported gain every sixth since beginning pandemic. This most obvious from lower household income preexisting overweight. also reported patterns had worsened: 70% increase consumption leisure time, 44% decrease 16% worsening habits (e.g., 27% stated eat more cake sweets). Children 10-12 severely affected.Negative effects are predominantly observed age low income, suggesting social disparity. Political action urgently needed tackle adverse consequences on childhood health.

Language: Английский

Citations

18

The Ongoing Impact of COVID-19 on Pediatric Obesity DOI Creative Commons
Domenico Iacopetta, Alessia Catalano, Jessica Ceramella

et al.

Pediatric Reports, Journal Year: 2024, Volume and Issue: 16(1), P. 135 - 150

Published: Feb. 2, 2024

In the developed world, pediatric obesity (PO) has been a major health concern since last century, and this condition may lead to detrimental life-long physical mental comorbidities. Currently, its prevalence increased in low- middle-income countries many high-income countries. Thus, provision of effective tailored care for children their families become vital. The social consequences COVID-19 pandemic are known everywhere, among these, it argued that had impact on PO. Overall, growth PO over decade enhanced by pandemic. During pandemic, children, adolescents young adults gained weight as population dealt with sedentary lifestyles changes food habits. review, we want highlight

Language: Английский

Citations

8