Differences between Health and Non-Health Science Students in Lifestyle Habits, Perceived Stress and Psychological Well-Being: A Cross-Sectional Study

Nutrients, Journal Year: 2024, Volume and Issue: 16(5), P. 620 - 620

Published: Feb. 23, 2024

The aim of this study was to investigate lifestyle habits in health and non-health science students from the University Split, Croatia, evaluate their association with perceived stress psychological well-being. We surveyed 783 during February–March 2021. Hierarchical multiple regression analysis used analysis. Health spent less time using screens, were sitting less, slept but also showed better compliance Mediterranean diet compared (10.6% vs. 5.9%). There no differences well-being perception between two groups. Female gender, lack sleep, daily time, anxiety, lower optimism associated higher students, while anxiousness more found be significant among students. Well-being positively BMI, having had COVID-19, being refreshed after waking up working days, adherence, perception, optimism, quality life, negatively TV anxiousness. Shorter sleep duration on non-working feeling life Identifying unhealthy is essential for implementing targeted interventions outcomes.

Language: Английский

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GLUT1-mediated microglial proinflammatory activation contributes to the development of stress-induced spatial learning and memory dysfunction in mice

Cell & Bioscience, Journal Year: 2024, Volume and Issue: 14(1)

Published: April 16, 2024

Abstract Background Stress is a recognized risk factor for cognitive decline, which triggers neuroinflammation involving microglial activation. However, the specific mechanism activation under stress and affects learning memory remains unclear. Methods The chronic mouse model was utilized to explore relationship between spatial impairment. effect of hippocampal hyperglycemia on evaluated through glucose-infusion incubation BV2 cells with high glucose. gain-and loss-of-function experiments were conducted investigate role GLUT1 in proinflammatory An adeno-associated virus (AAV) employed specifically knockdown microglia assess its impact stressed-mice. Results Herein, we found that induced remarkable neuroinflammation, involved development stress-related Mechanistically, elevated glucose level post-stress revealed be key regulator via increasing expression GLUT1. overexpression promoted phenotype while inhibiting function mitigated this Furthermore, downregulation stressed-mice relieved activation, injury. Finally, NF-κB signaling pathway demonstrated regulatory microglia. Conclusions We demonstrate induce contributing stress-associated dysfunction. These findings highlight significant interplay metabolism inflammation, presenting possible therapeutic target disorders.

Language: Английский

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Key psychosocial issues in medical care

Acta Psychiatrica Scandinavica, Journal Year: 2024, Volume and Issue: 149(5), P. 368 - 377

Published: Feb. 1, 2024

Abstract Objective The aim of this review is to illustrate an innovative framework for assessing the psychosocial aspects medical disorders within biopsychosocial model. It based on clinimetrics, science clinical measurements. may overcome limitations DSM‐5 in identifying highly individualized responses at experiential, behavioral, and interpersonal levels. Method A critical clinimetric formulations model setting disease was performed. References were identified through searches from PubMed English articles human subjects published January 1982 October 2023. Results Clinimetric methods classification have been found deserve special attention four major areas: allostatic load (the cumulative cost fluctuating heightened neural or neuroendocrine environmental stressors); health attitudes behavior; persistent somatization; demoralization irritable mood. This type assessment, integrated with traditional psychiatric nosography, disclose pathophysiological links provide characterizations that demarcate prognostic therapeutic differences among patients who otherwise seem deceptively similar because they same diagnosis. be value a number situations, such as: high level disability compromised quality life relation what expected by status; delayed partial recovery; insufficient participation self‐management and/or rehabilitation; failure resume healthy role after convalescence; unhealthy lifestyle; attendance facilities disproportionate detectable disease; lack treatment adherence; illness denial. Conclusions approach assessment key variables lead unique individual profiles, take into account both biology biography. offer new opportunities integrating perspectives.

Language: Английский

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The link between spirituality and longevity

Aging Clinical and Experimental Research, Journal Year: 2024, Volume and Issue: 36(1)

Published: Feb. 11, 2024

Abstract We are facing an inverted demographic pyramid with continuously growing aged populations around the world. However, advances that prolong physical life not always contemplate its psychological and social dimensions. Longevity is a complex outcome influenced by wide range of factors, including genetics, lifestyle choices, access to healthcare, socio-economic conditions, other environmental factors. These factors have been generally considered in compelling research seeks determinants longevity, particularly those concerning personal socioeconomic molecular mechanisms proposed mediate these effects. Nonetheless, fundamental aspects can affect health well-being, such as spirituality religiosity, somehow left aside despite numerous epidemiological studies showing higher levels spirituality/religiosity associated lower risk mortality, even after adjusting for relevant confounders. Because dimensions great value patients, overlooking them leave feelings neglect lack connection system clinicians charge their care. Integrating religiosity assessment intervention programs into clinical care help each person obtain better complete well-being also allowing achieve highest standards holistic, person-centered The present narrative review aims explore available evidence relationship between longevity discusses possible explain relationship.

Language: Английский

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The influence of everyday emotions on mucosal immunity: An intensive longitudinal modeling approach

Psychophysiology, Journal Year: 2024, Volume and Issue: 61(8)

Published: March 29, 2024

Mucosal immunity is a multifaceted system of immunological responses that provides barrier against pathogenic invasion and can be regulated by psychosocial neuroendocrine factors. The present study aims to elucidate the association between everyday emotional states, emotion regulation skills, mucosal utilizing an ambulatory assessment approach. 30 healthy subjects (61% male; M = 30.18 years old) completed questionnaire (PANAS) collected saliva samples via passive drool determine salivary immunoglobulin-A (S-IgA) excretion rate three times day over period 1 week. In multi-level model, influence emotions on S-IgA, both within-subject between-subject level, was estimated. We found most variation in S-IgA (74%) accounted for changes rather than stable differences. On negative had significant positive effect levels (b 1.87, p .015), while no effect. This moderated individual with higher skills corresponding smaller effects -2.67, .046). Furthermore, decreased course day, indicating circadian rhythmicity -0.13, .034). These results highlight possibilities intensive longitudinal data investigate covariance psychological states time.

Language: Английский

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