Effects of in Utero SARS-CoV-2 Exposure on Newborn Health Outcomes DOI Creative Commons
Margaret H. Kyle, Dani Dumitriu

Encyclopedia, Journal Year: 2022, Volume and Issue: 3(1), P. 15 - 27

Published: Dec. 26, 2022

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over 600 million people worldwide, including millions of pregnant women. While newborns exposed to other viruses in utero are sometimes at high risk for vertical transmission, a substantial body literature since early 2020 demonstrated that transmission SARS-CoV-2 from mother neonate is rare, and who do become with generally have favorable outcomes. In this review, the authors evaluate existing on its potential mechanisms discuss short- long-term health outcomes were utero. conclude adverse neonatal infant/child unlikely, but neonates prenatal maternal infection may be slightly higher preterm birth, possibly related increased COVID-19 disease women, placental changes, or timing. Ultimately, need additional longer-term follow-up data population highlighted.

Language: Английский

A critical insight into occurrence and fate of polycyclic aromatic hydrocarbons and their green remediation approaches DOI
Archana Kumari,

Vidisha Upadhyay,

Sunil Kumar

et al.

Chemosphere, Journal Year: 2023, Volume and Issue: 329, P. 138579 - 138579

Published: April 7, 2023

Language: Английский

Citations

39

Impact of perinatal COVID on fetal and neonatal brain and neurodevelopmental outcomes DOI Open Access

Andrea C. Brum,

Néstor Vain

Seminars in Fetal and Neonatal Medicine, Journal Year: 2023, Volume and Issue: 28(2), P. 101427 - 101427

Published: March 8, 2023

Language: Английский

Citations

13

Association of Antenatal COVID-19–Related Stress With Postpartum Maternal Mental Health and Negative Affectivity in Infants DOI Creative Commons
Susanne Schweizer, Jack L. Andrews, Karina Grunewald

et al.

JAMA Network Open, Journal Year: 2023, Volume and Issue: 6(3), P. e232969 - e232969

Published: March 14, 2023

Importance Antenatal stress is a significant risk factor for poor postpartum mental health. The association of pandemic-related with outcomes among mothers and infants is, however, less well understood. Objective To examine the antenatal COVID-19–related maternal health infant outcomes. Design, Setting, Participants This cohort study was conducted 318 participants in COVID-19 Risks Across Lifespan study, which took place Australia, UK, US. Eligible reported being pregnant at first assessment wave between May 5 September 30, 2020, completed follow-up October 28, 2021, April 24, 2022. Main Outcomes Measures assessed Pandemic Anxiety Scale (score range, 0-4, higher scores indicating greater stress). 8-item Patient Health Questionnaire 0-3, more frequent symptoms depression) used to measure depression each time point, 7-item General Disorder scale anxiety) generalized anxiety point. At follow-up, distress 10-item Postpartum Distress Measure distress), (negative positive affectivity orienting behavior) were captured Infant Behavior 1-7, that exhibited affect/behavior frequently). Results included women (mean [SD] age, 32.0 [4.6] years) from Australia (88 [28%]), US (94 [30%]), UK (136 [43%]). significantly associated (β = 0.40 [95% CI, 0.28-0.53]), 0.32 0.23-0.41]), 0.35 0.26-0.44]), as negative 0.45 0.14-0.76]). findings remained consistent across range sensitivity analyses. Conclusions Relevance this suggest targeting stressors period may improve Pregnant individuals should be classified vulnerable group during pandemics considered public priority, not only terms physical but also

Language: Английский

Citations

11

Pandemic babies: a systematic review of the association between maternal pandemic-related stress during pregnancy and infant development DOI Creative Commons
Sarah Nazzari, Miriam Paola Pili,

Yaren Günay

et al.

Neuroscience & Biobehavioral Reviews, Journal Year: 2024, Volume and Issue: 162, P. 105723 - 105723

Published: May 16, 2024

The COVID-19 pandemic, with its far-reaching influence on daily life, constituted a highly stressful experience for many people worldwide, jeopardizing individuals' mental health, particularly in vulnerable populations such as pregnant women. While growing body of evidence links prenatal maternal stress to biological and developmental alterations offspring, the specific impact exposure pandemic-related (PRS) infant development remains unclear. A comprehensive literature search was performed October 2023 according PRISMA guidelines, which yielded total 28 records. selected papers investigated vast range outcomes offspring large methodological variations. reviewed studies showed mixed results. Either direct associations between PRS during pregnancy temperament socio-emotional development, or indirect links, mediated by emerged most studies. Furthermore, associated epigenetic brain although were limited number. Collectively, findings contribute deeper understanding role early adverse exposures development.

Language: Английский

Citations

4

Postpartum Maternal Stress is Unrelated to the Infant Fecal Microbiome, but is Associated With the Human Milk Microbiome in Exclusively Breastfeeding Mother‐Infant Dyads: The Mother‐Infant Microbiomes, Behavior, and Ecology Study (MIMBES) DOI Creative Commons
Elizabeth A. Holdsworth, Janet E. Williams, Ryan M. Pace

et al.

American Journal of Human Biology, Journal Year: 2025, Volume and Issue: 37(5)

Published: May 1, 2025

ABSTRACT Objectives This study aimed to evaluate whether postpartum maternal stress is associated with infant gastrointestinal microbiome composition and diversity, this relationship may be mediated by caregiving breastfeeding behaviors human milk (HMM) composition. Methods Infant fecal samples were collected from 51 exclusively mother‐infant dyads in the Pacific Northwest between 1 6 months postpartum. sequencing read counts > 773 ( n = 48) 200 46) analyzed for bacterial alpha diversity (richness, Shannon diversity), beta (Bray–Curtis dissimilarity), genera differential abundances. (IFM) measures tested associations mothers' self‐reported Parenting Stress Index total subscale scores regression envfit (beta MaAsLin2 (genera abundance) models. Potential mediators of IFM explored (observed time breastfeeding; maternal–infant physical contact frequency; HMM abundance). Results Maternal was not or diversities. Two subscales abundances Erysipelotrichaceae UCG‐003 (positively) Eggerthella (negatively) feces. two (Role Restriction, Attachment) positively (q attachment 0.07) negatively richness 0.08, q role 0.03). Conclusions Postpartum consistently during exclusive breastfeeding. However, suggesting that might influence other developmental pathways infant.

Language: Английский

Citations

0

Maternal perceived stress and infant behavior during the COVID-19 pandemic DOI Creative Commons
Holly Bradley,

Dana Fine,

Yasmin Minai

et al.

Pediatric Research, Journal Year: 2023, Volume and Issue: 94(6), P. 2098 - 2104

Published: July 27, 2023

Abstract Background Maternal stress has negative consequences on infant behavioral development, and COVID-19 presented uniquely stressful situations to mothers of infants born during the pandemic. We hypothesized that with higher levels perceived pandemic would report regulatory problems including crying interrupted sleep patterns. Methods As part 6 sites a longitudinal study, completed Perceived Stress Scale, Brief Infant Sleep Questionnaire, an Crying survey at ( n = 433) 12 344) months age. Results stress, which remained consistent age, was significantly positively correlated time taken settle infants. Although maternal not uninterrupted length, put correlated. also amount fussiness reported months. Conclusions Mothers who problems, specifically Examining how varying behaviors relate overall developmental status over is important next step. Impact Women giving birth Scale old, more disruptive patterns in their old. Sleeping excessive infancy are two known risk factors for emotional issues later childhood. This paper one first studies highlighting associations between

Language: Английский

Citations

9

Infant regulatory problems and the quality of dyadic emotional connection—a proof-of-concept study in a multilingual sample DOI Creative Commons
Julia Jaekel, Anne-Kathrin Dathe,

Maire Brasseler

et al.

Frontiers in Child and Adolescent Psychiatry, Journal Year: 2024, Volume and Issue: 2

Published: Jan. 5, 2024

Background and aims Close autonomic emotional connections with others help infants reach maintain homoeostasis. In recent years, infant regulatory problems (RPs, i.e., crying, sleeping, feeding or eating problems) have surged. This study has two aims: (1) Provide proof-of-concept that dyadic connection between parents can be reliably assessed a brief screening, irrespective of language culture. (2) Assess in heterogeneous pilot sample whether the persistence RPs during infancy is negatively associated quality connection. Methods 30 children aged 3–68 months (47% female) their (83% mothers) were regular neonatal follow-up visits Germany. Seven (23%) dyads immigrants whose primary was not German. At each assessment, paediatricians asked about infant's problems. Dyadic interactions rated by multilingual team standardised universal Welch Emotional Connection Screen (uWECS) on four dimensions (attraction, vocalisation, facial communication, sensitivity/reciprocity). Results Aim 1: An international raters trained remotely to rate uWECS. Reliability α > .90 standard achieved mismatches (i.e., all scored several videos languages they did understand). Intra-class correlation coefficients ( ICCs ) among five main for uWECS ranged from .98–.99. 2: Infants n = 15 longitudinally) had mean RP scores 1.20 (SD 1.26). Dyads 7.06 2.09). Linear regression analysis showed more persistent lower [ β -.53, 95% CI (-1.47, -.18), p .017], after controlling child sex gestational age. Conclusion provides mutual socio-culturally linguistically samples uWECS, screening easily implemented clinical practice. Pilot data suggests are Replication these findings larger warranted. Future studies need address how facilitate successful emotion regulation today's future generations.

Language: Английский

Citations

3

Does parental mental health mediate the association between parents' perceived stress and parent-infant bonding during the early COVID-19 pandemic? DOI Creative Commons
Carmen Power, Victoria Weise, Judith T. Mack

et al.

Early Human Development, Journal Year: 2024, Volume and Issue: 189, P. 105931 - 105931

Published: Jan. 5, 2024

The spread of the COVID-19 virus was declared a pandemic in March 2020. New restrictions such as 'lockdowns' and 'social distancing' created challenges for individuals' work-life balance, financial situation, family life, physical mental health. global population's stress levels rose response to these changes, leading widespread deterioration One group particularly affected parents infants very young children. Poor parental health may disrupt parent-infant bonding, with negative consequences infant well-being development.

Language: Английский

Citations

3

Maternal–prenatal stress and depression predict infant temperament during the COVID-19 pandemic DOI Creative Commons
Jessica L. Buthmann, Jonas G. Miller, Ian H. Gotlib

et al.

Development and Psychopathology, Journal Year: 2022, Volume and Issue: 36(1), P. 161 - 169

Published: Nov. 8, 2022

Abstract Researchers have begun to examine the psychological toll of ongoing global COVID-19 pandemic. Data are now emerging indicating that there may be long-term adverse effects pandemic on new mothers and children born during this period. In a longitudinal study maternal mental health child emotional development pandemic, we conducted online assessments cohort women at two time points: when they were pregnant beginning surge in United States (baseline, N = 725), approximately 1 year postpartum (follow-up, 296), examining prenatal postnatal health, pandemic-related stress, infant temperament. Pandemic-related stress baseline was associated with concurrent depressive symptoms negative affect follow-up. Baseline follow-up symptoms, which turn also affect. pregnancy enduring These findings important implications for our understanding who utero

Language: Английский

Citations

12

Impact of COVID-19 Related Maternal Stress on Fetal Brain Development: A Multimodal MRI Study DOI Open Access
Vidya Rajagopalan, William Reynolds, Jeremy Zepeda

et al.

Journal of Clinical Medicine, Journal Year: 2022, Volume and Issue: 11(22), P. 6635 - 6635

Published: Nov. 9, 2022

Disruptions in perinatal care and support due to the COVID-19 pandemic was an unprecedented but significant stressor among pregnant women. Various neurostructural differences have been re-ported fetuses infants born during compared pre-pandemic counterparts. The relationship between maternal stress related disruptions fetal brain is yet unexamined.Pregnant participants with healthy pregnancies were prospectively recruited 2020-2022 greater Los Angeles Area. Participants completed multiple self-report assessments for experiences of disruptions, perceived stress, coping behaviors underwent MRI. Maternal exposures correlated quantitative multimodal MRI measures development using multivariate models.Increased perception positively normalized brainstem volume (suggesting accelerated maturation). In contrast, increased reduced global temporal functional variance connectivity).We report alterations structure activity associated suggesting altered programming. Long term follow-up studies are required better understand sequalae these early multi-modal pandemic.

Language: Английский

Citations

11