Cited by As Far as the Eye Can See: Importance of Myopia as a Pressing Public Health Need

As Far as the Eye Can See: Importance of Myopia as a Pressing Public Health Need DOI

et al.

Ophthalmology Science, Journal Year: 2023, Volume and Issue: 4(1), P. 100438 - 100438

Published: Nov. 22, 2023

Not long ago, myopia was generally regarded as a benign refractive error that readily corrected with spectacles, contact lenses, and, more recently, surgery. The past two decades have seen seismic shift in how we an ophthalmic community view myopia.1Morgan I.G. Ohno-Matsui K. Saw S.M. Myopia.Lancet. 2012; 379: 1739-1748Abstract Full Text PDF PubMed Scopus (1239) Google Scholar reasons include:•its rapidly increasing prevalence due to increasingly intensive education and common indoor lifestyles;2Morgan French A.N. Ashby R.S. et al.The epidemics of myopia: Aetiology prevention.Prog Retin Eye Res. 2018; 62: 134-149Crossref (582) Scholar,3Pan C.W. Ramamurthy D. Worldwide risk factors for myopia.Ophthalmic Physiol Opt. 32: 3-16Crossref (603) Scholar•its role increased ocular disease4Haarman A.E.G. Enthoven C.A. Tideman J.W.L. Complications Myopia: A Review Meta-Analysis.Invest Ophthalmol Vis Sci. 2020; 61: 49Crossref (234) visual impairment;5Bullimore M.A. Ritchey E.R. Shah S. Risks Benefits Myopia Control.Ophthalmology. 2021; 128: 1561-1579Abstract (71) Scholar, 6Bullimore Brennan N.A. underestimated uncorrectable impairment the United States.Sci Rep. 2023; 1315283Crossref (0) 7Tideman J.W. Snabel M.C. Tedja M.S. al.Association Axial Length With Risk Uncorrectable Visual Impairment Europeans Myopia.JAMA ophthalmology. 2016; 134: 1355-1363Crossref and•the emergence evidence-based interventions delay its onset8Yam J.C. Zhang X.J. Y. al.Effect Low-Concentration Atropine Eyedrops vs Placebo on Incidence Children: LAMP2 Randomized Clinical Trial.JAMA. 329: 472-481Crossref (14) slow progression.9Logan N.S. Bullimore Optical control.Eye (Lond). https://doi.org/10.1038/s41433-023-02723-5Crossref (2) Scholar,10Jawaid I. Saunders Hammond C.J. al.Low concentration atropine narrative review evidence Kingdom based practitioners.Eye https://doi.org/10.1038/s41433-023-02718-2Crossref While sight-threatening consequences occur later life, onset need be commenced early childhood, while progression implemented soon possible after onset.11Bullimore Juvenile-onset myopia-who treat evaluate success.Eye https://doi.org/10.1038/s41433-023-02722-6Crossref (1) aim is reduce both overall myopia, well high associated pathological changes. In some parts world, notably East Southeast Asia, around 80% children completing 12 years schooling are myopic, 10-30% highly myopic at loss vision various diseases.5Bullimore Singapore,12Drury V.B. Finkelstein E. al.A new community-based outdoor intervention increase physical activity Singapore children: findings from focus groups.Ann Acad Med Singap. 2013; 42: 225-231Crossref Taiwan, recently mainland China,13Morgan Jan C.L. China Turns School Reform Control Epidemic: Narrative Review.Asia Pac J (Phila). 2022; 11: 27-35Crossref (23) developed prevention control programs. other there also increasing, but limited data States. young adults, aged 20-39 years, most recent NHANES survey close 50%, 7%,14Vitale Ellwein L. Cotch M.F. al.Prevalence States, 1999-2004.Arch Ophthalmol. 2008; 126: 1111-1119Crossref (388) these non-cycloplegic refractions will likely lead significant overestimation prevalence.15Fotouhi A. Morgan Iribarren R. al.Validity noncycloplegic refraction assessment errors: Tehran Study.Acta 90: 380-386Crossref Scholar,16Morgan Fotouhi Grzybowski Cycloplegic gold standard epidemiological studies.Acta 2015; 93: 581-585Crossref (111) Because link maculopathy, or macular degeneration, has been extensively studied17Hayashi K, Shimada N, al. Long-term pattern maculopathy: natural history study. Ophthalmology 2010;117:1595-1611, 611 e1-1611.Google classified.18Ohno-Matsui Kawasaki Jonas J.B. al.International photographic classification grading system maculopathy.Am 159: 877-883 e7Abstract It leading cause impairment,19Hu J.Y. Yan Chen Y.D. al.Population-based prevalence, causes, blindness aging Chinese metropolitan population.Int 2017; 10: 140-147PubMed 20Hsu W.M. Cheng C.Y. Liu J.H. causes elderly population Taiwan: Shihpai Study.Ophthalmology. 2004; 111: 62-69Abstract (305) 21Tang Wang X. J. Causes Adult Population: Taizhou 122: 1480-1488Abstract impact predicted dramatically.22Fricke T.R. Jong M. Naidoo K.S. al.Global degeneration temporal trends 2000 through 2050: systematic review, meta-analysis modelling.Br 102: 855-862Crossref (182) maculopathy increases level myopia,23Bullimore Control: Why Each Diopter Matters.Optom 2019; 96: 463-465Crossref (104) less severe than –6 D accounts can account over half cases where remains relatively low.24Wong Y.L. Sabanayagam C. Ding al.Prevalence, Factors, Impact Myopic Macular Degeneration Functioning Among Adults Singapore.Invest 59: 4603-4613Crossref (79) This led popularized phrases such "there no safe myopia"25Flitcroft D.I. complex interactions retinal, optical environmental aetiology.Prog 31: 622-660Crossref (503) "every diopter matters."23Bullimore statement by American Academy "the population-based burden lower degrees considerable."26Modjtahedi B.S. Abbott R.L. Fong D.S. al.Reducing Global Burden Delaying Onset Reducing Progression Academy's Task Force Myopia.Ophthalmology. 816-826Abstract (39) problem worldwide, because it age-related disease, many populations aging. Science journal Ophthalmology, who championed importance pressing public health need. 2019, created recognition "substantial global complications." Board Trustees believes "myopia high-priority impairment, warranting timely evaluation synthesis scientific literature formulation action plan address issue different perspectives. includes physicians care providers, patients their families, schools, local national agencies; defining policies ameliorate patients' access appropriate therapy promote effective interventions; fostering promising avenues research." More sponsored congressional briefing raise awareness crisis. Michael Repka, MD, pediatric ophthalmologist Johns Hopkins University Medical Director Governmental Affairs Jeffrey Walline, OD, PhD, Associate Dean Research Ohio State College Optometry President-Elect Optometry, spoke lawmakers staff rising rates investing research identify potential solutions. Interventions fall under purview U.S. Food Drug Administration (FDA). only one approved clinical childhood products ongoing evaluation, world. FDA sought input learned societies, including published report design trials investigating effectiveness safety devices.27Walline J.J. Robboy M.W. Hilmantel G. al.Food Administration, Association Pediatric Strabismus, Optometric Association, Society Cataract Refractive Surgery, Contact Lens Ophthalmologists Co-Sponsored Workshop: Controlling Lenses Future Devices.Eye Lens. 44: 205-211PubMed progress field dramatic, remain unanswered questions. therefore pleased announce Special Issue goal spanning basic aspects myopia. focuses preclinical science, phase 1, 2 trials, bioinformatics. So all would appropriate. We invite submissions describing original well-published authors could summarize present data. Reviews welcome, any should unique not duplicate previous efforts. Some examples include, to, studies established emerging methods onset, biochemical signals modulate growth, animal models, genetics, complications Ultimately, clinically relevant, comprehensible clinicians, eventually practice. start accepting manuscripts January 2024 open end December. Submissions subjected journal's usual rigorous peer-review—the acceptance rate 27%. article processing charge 50%. entirely online, when accepted. Nonetheless, special dedicated manuscripts, grouped according subject matter. create central place experts provide variety insight into problem. As guest editors, grateful this opportunity look forward engaging actively issue.

Language: Английский

Myopia control: Seeing beyond efficacy DOI

Mark A. Bullimore, Monica Jong, Noel A. Brennan

et al.

Optometry and Vision Science, Journal Year: 2024, Volume and Issue: 101(3), P. 134 - 142

Published: March 1, 2024

SIGNIFICANCE The availability of a range effective myopia control modalities enables the clinician to exercise judgment when discussing treatment plan with patient and their parents. This article outlines important considerations beyond efficacy. Clinically meaningful may be attained some spectacle lenses, select soft contact concentrations atropine, overnight orthokeratology. Given that satisfactory efficacy can achieved modalities, other factors should considered deciding upon best intervention for given child. Four key factors—compliance, quality vision, life, safety—are discussed in this review. Compliance directly impacts regardless modality is most consideration, as it influenced by vision comfort. Daily disposal lenses orthokeratology are generally associated high compliance, provide better vision-related life than spectacles, carry very low risk used appropriately. A further benefit elimination need optical correction during day.

Language: Английский

Citations

Myopia Control: Are We Ready for an Evidence Based Approach? DOI

Leila Sara Eppenberger, Andrzej Grzybowski, Leopold Schmetterer

et al.

Ophthalmology and Therapy, Journal Year: 2024, Volume and Issue: 13(6), P. 1453 - 1477

Published: May 7, 2024

Myopia and its vision-threatening complications present a significant public health problem. This review aims to provide an updated overview of the multitude known emerging interventions control myopia, including their potential effect, safety, costs. A systematic literature search three databases was conducted. Interventions were grouped into four categories: environmental/behavioral (outdoor time, near work), pharmacological (e.g., atropine), optical (spectacles contact lenses), novel approaches such as red-light (RLRL) therapies. Review articles original on randomized controlled trials (RCT) selected. From initial 3224 retrieved records, 18 reviews 41 reporting results from RCTs included. While there is more evidence supporting efficacy low-dose atropine certain myopia-controlling lenses in slowing myopia progression, about newer interventions, spectacle defocus incorporated multiple segments highly aspheric lenslets) limited. Behavioral i.e., increased outdoor seem effective for preventing onset if implemented successfully schools homes. environmental spectacles are regarded generally safe, lenses, RLRL may be associated with adverse effects. All except behavioral change, tied moderate high expenditures. Our suggests that recommended prescribed basis accessibility clinical practice patterns, which vary widely around world. Clinical indicate short- medium-term reducing progression various but none have demonstrated long-term effectiveness adulthood. There unmet need unified consensus strategies balance risk these methods personalized management.

Language: Английский

Citations

Novel Lenslet-ARray-Integrated Spectacle Lenses for Myopia Control DOI

Binbin Su, Pauline Cho, Stephen J. Vincent

et al.

Ophthalmology, Journal Year: 2024, Volume and Issue: 131(12), P. 1389 - 1397

Published: July 6, 2024

Language: Английский

Citations

Juvenile-onset myopia—who to treat and how to evaluate success DOI

Mark A. Bullimore, Noel A. Brennan

Eye, Journal Year: 2023, Volume and Issue: 38(3), P. 450 - 454

Published: Sept. 14, 2023

Language: Английский

Citations

Chromatic cues for the sign of defocus in the peripheral retina DOI

Len Zheleznyak, Chang Liu, Simon Winter

et al.

Biomedical Optics Express, Journal Year: 2024, Volume and Issue: 15(9), P. 5098 - 5098

Published: Aug. 2, 2024

Detecting optical defocus at the retina is crucial for accurate accommodation and emmetropization. However, characteristics of ocular are not fully understood. To bridge this knowledge gap, we simulated polychromatic retinal image quality by considering both monochromatic wavefront aberrations chromatic eye, in fovea periphery (nasal visual field). Our study revealed two main findings: (1) interact to provide a signal (chromatic anisotropy) discern positive from negative (2) that anisotropy exhibited notable differences among refractive error groups (myopes, emmetropes hyperopes). These findings could enhance our understanding underlying mechanisms detection their subsequent implications myopia control therapies. Further research needed explore architecture's ability utilize signals identified study.

Language: Английский

Citations

Eye growth and myopia progression following cessation of myopia control therapy with a dual-focus soft contact lens DOI

Paul Chamberlain, David Hammond, Arthur Bradley

et al.

Optometry and Vision Science, Journal Year: 2025, Volume and Issue: unknown

Published: March 25, 2025

This 7-year clinical study assessed the impact of age and number years myopia control treatment with MiSight 1 day (omafilcon A; CooperVision, Inc., Pleasanton, CA) dual-focus contact lenses on post-treatment eye growth progression. Growth progression after were ceased returned to age-normal levels retaining prior accrued gains. aimed assess refractive changes cessation prolonged a lens. Eighty-three subjects completing 6-year trial lens (MiSight day) continued into follow-on 1-year "wash-out" phase in which all fit single-vision (Proclear day, omafilcon Inc.). Right left data analyzed from 38 6 (T6) 40 receiving during 4 (T3). Axial length cyclopleged spherical equivalent errors monitored annually for 7 years. Expected axial if had not been started estimated by extrapolating untreated myopic eyes collected 3 using population-based estimates effects rates. During year 7, annualized 0.09 ± (T3) 0.10 mm/y (T6), -0.23 0.36 -0.21 0.40 D/y respectively, each slightly greater than observed previous (0.07 0.12 [T3] 0.08 0.07 mm [T6], -0.04 0.34 -0.13 0.42 D [T6]). Year was less older (11 12 at baseline, -0.17 D/0.05 mm) younger (8 10 -0.26 D/0.13 subgroup. Years (3 vs. 6) did influence or A following found rates similar those expected these ages. finding reveals that gains retained neither amplified nor diminished treatment.

Language: Английский

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Optimising non‐cycloplegic screening strategies for early detection of pre‐myopia and myopia in young children DOI

Síofra Harrington, Michael Moore, James Loughman

et al.

Ophthalmic and Physiological Optics, Journal Year: 2025, Volume and Issue: unknown

Published: May 14, 2025

Abstract Purpose Early detection of myopia is essential to delay its onset and progression. Pre‐myopia, defined by an inadequate hyperopic reserve, increases risk in childhood. However, effective screening methods remain limited. This study aimed develop practical non‐cycloplegic for pre‐myopia 6‐ 7‐year‐olds support earlier interventions. Methods cross‐sectional 621 Irish schoolchildren (mean age: 7.12 ± 0.45 years; 51.8% boys) assessed uncorrected distance visual acuity (UDVA). Cycloplegic spherical equivalent refraction (SER) classified refractive status (myopia: SER ≤ −0.50D; pre‐myopia: > −0.50 0.75D). Pre‐ post‐cycloplegic were measured using the Welch Allyn Spot Vision Screener Dong‐Yang Rekto‐ORK 11, respectively. Axial length (AL) corneal radius (CR) with Zeiss IOLMaster parental history via questionnaire. Logistic regression ROC curves evaluated methods. Results Pre‐myopia prevalence was 24.3% (95% confidence intervals (CI): 29.3–36.2), 3.3% (CI: 2.5–5.5). UDVA had area under curve (AUC) (CI) = 0.72 (0.59–0.86) 0.42 (0.36–0.47) detecting pre‐myopia, For discrimination, SER, AL, AL/CR AUCs 0.67 (0.62–0.72), 0.69 (0.64–0.74) 0.59 (0.53–0.64), The best method combined (AUC (0.67–0.76)). Including or did not improve results. detection, SER:0.84 (0.72–0.97), AL:0.88 (0.82–0.95), AL/CR:0.84 (0.75–0.94) myopia:0.62 (0.48–0.75). AL 0.94 (0.90–0.99). Adding AUC 0.93 (0.87–0.99) but adding achieved 0.95 Conclusion While alone provided acceptable discrimination myopia, it insufficient pre‐myopia. Non‐cycloplegic relatively poor performance improved when ratio. results combining axial measures.

Language: Английский

Citations

Commonly Held Beliefs About Myopia That Lack a Robust Evidence Base: 2025 Update DOI

Noel A. Brennan,

Xu Cheng,

Monica Jong

et al.

Eye & Contact Lens Science & Clinical Practice, Journal Year: 2025, Volume and Issue: unknown

Published: May 21, 2025

Purpose: To subject a number of areas contention in the myopia field to evidence-based scrutiny. Method: The 10 topics from our previous review were revisited, and nine new also critiqued with emphasis on recent peer-reviewed literature. Results: following observations made: 0.01% atropine should not be considered frontline control treatment; role relative peripheral hyperopia development progression remains unclear; undercorrection probably does slow progression; treatment efficacy diminishes time; percentage is misleading metric efficacy; handheld digital devices have been proven myopiagenic; more time outdoors may myopic shift similar extent children without myopia; daylight responsible for only part impact outdoor all myopia, just high carries risk visually threatening complications; premyopia real condition. Furthermore, disease; accommodation lag measurement artifact; adult significant; past flawed indicator initiate control; fast mean nonresponse single vision soft contact lenses are red light therapy safe; lens wear rebound cannot assessed by comparing during treatment. Conclusions: continues evolve some conflicts resolved, ongoing confusion, uncertainties emerging.

Language: Английский

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Real–world outcomes on myopia management efficacy of diverse segmented defocus optics (DSDO) and defocus incorporated multiple segments (DIMS) spectacle lenses in Chinese children: An initial 12–month prospective clinical study DOI

Yuzhuo Fan,

Hui-Hui Chu,

Zisu Peng

et al.

Journal of Optometry, Journal Year: 2025, Volume and Issue: 18(1), P. 100533 - 100533

Published: Jan. 1, 2025

To investigate the 12-month effectiveness of Diverse Segmented Defocus Optics (DSDO) and Incorporated Multiple Segments (DIMS) spectacle lenses in a real-world clinical population myopic pre-myopic Chinese children. About 364 subjects prescribed DSDO or DIMS were enrolled. Axial length (AL) cycloplegic spherical equivalent refraction (SER) changes over 12 months measured. The further divided into age sub-group (6-9; 10-14) SER (+0.75D≤SER<-0.50D; -0.50D≤SER<-2.00D; -2.00D≤SER<-4.00D; SER≤-4.0D). Contrast sensitivity visual experience also reported. rate myopia progression was compared with historical single-vision spectacles (SVS) data to evaluate regime. 317 analyzed. At 12-month, AL group 0.16±0.16 mm 0.21±0.22 mm, respectively (P = 0.0202). had better control effect +0.75D≤SER<-0.50D SER≤-2.0D sub-groups. proportion participants no greater than 0.20 elongation 65.00% 55.41% separately. Myopia 47%-69% 33%-62% SVS lenses. Both retarded elongation. showed more stable comparing DIMS, especially groups sub-groups older patients. initial potential prevention children data. However, small sample pre-myopes this study are key limitations. Further research is needed confirm understand DSDO's role for

Language: Английский

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Peripheral Defocus in Orthokeratology Myopia Correction: Systematic Review and Meta-Analysis DOI

António Queirós, Inês Pinheiro, Paulo Fernandes

et al.

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(3), P. 662 - 662

Published: Jan. 21, 2025

Background: This study aimed to assess the effect of peripheral defocus with orthokeratology lenses (PDOK) on myopia control in children and adolescents through a systematic review meta-analysis. Methods: A comprehensive search was conducted PubMed Web Science databases identify randomized controlled trials (RCTs) cohort studies PDOK, using keywords “peripheral refraction” “orthokeratology”. Studies were included if they reported spherical equivalent (M) refraction at 25° and/or 30° accompanying statistical data along horizontal meridian before after treatment. From initial 133 studies, those excluded nine non-English publications, 18 reviews, five meta-analyses, four 88 not meeting inclusion criteria. Results: Nine (three RCTs six studies) included, involving 259 participants aged 30 years baseline refractive error M = −2.44 ± 0.27 D, treatment duration ranging from 14 days 12 months. All showed an increase myopic nasal (−2.55 1.10 D) temporal (−2.79 0.75 eccentricities, averaging −2.67 0.95 D across both. The overall induced −2.56 (95% CI: −2.21 −2.91, Z 14.33, p < 0.001), according forest plot analysis. durations up one year higher blur (M −2.69 95% −2.48 −2.89, 25.93, 0.001) compared shorter treatments less than three months −2.39 −1.76 −3.02, 7.41, 0.001). Conclusions: Orthokeratology effectively induce eccentricity over both short- long-term adolescents, suggesting potential benefits for these age groups.

Language: Английский

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