Small,
Journal Year:
2020,
Volume and Issue:
16(48)
Published: Nov. 5, 2020
Abstract
Luminescence
nanothermometry
is
promising
for
noninvasive
probing
of
temperature
in
biological
microenvironment
at
nanometric
spatial
resolution.
Yet,
wavelength‐
and
temperature‐dependent
absorption
scattering
tissues
distort
measured
spectral
profile,
rendering
conventional
luminescence
nanothermometers
(ratiometric,
intensity,
band
shape,
or
shift)
problematic
vivo
determination.
Here,
a
class
lanthanide‐based
nanothermometers,
which
are
able
to
provide
precise
reliable
readouts
varied
tissue
depths
through
NIR‐II
lifetime,
described.
To
achieve
this,
an
inert
core/active
shell/inert
shell
structure
tiny
nanoparticles
(size,
13.5
nm)
devised,
thermosensitive
lanthanide
pairs
(ytterbium
neodymium)
spatially
confined
the
thin
middle
(sodium
yttrium
fluoride,
1
nm),
ensuring
being
homogenously
close
surrounding
environment
while
protected
by
outmost
calcium
fluoride
(CaF
2
,
≈2.5
that
shields
out
bioactive
milieu
interferences.
This
ternary
enables
consistently
resolve
changes
up
4
mm
tissues,
having
high
relative
sensitivity
1.4–1.1%
°C
−1
physiological
range
10–64
°C.
These
lifetime‐based
nanoprobes
allow
diagnosis
murine
inflammation,
mapping
distribution
profile
nanoprobes‐interrogated
area.
Journal of Applied Physics,
Journal Year:
2020,
Volume and Issue:
128(4)
Published: July 22, 2020
Following
astonishing
growth
in
the
last
decade,
field
of
luminescence
thermometry
has
reached
stage
becoming
a
mature
technology.
To
achieve
that
goal,
further
developments
should
resolve
inherent
problems
and
methodological
faults
to
facilitate
its
widespread
use.
This
perspective
presents
recent
findings
thermometry,
with
aim
providing
guide
for
reader
paths
which
this
is
currently
directed.
Besides
well-known
temperature
read-out
techniques,
are
outlined
compared
terms
performance,
some
recently
introduced
methods
have
been
discussed
more
detail.
These
include
intensity
ratio
measurements
exploit
emissions
from
excited
lanthanide
levels
large
energy
differences,
dual-excited
time-resolved
single-band
ratiometric
methods,
phase-angle
readouts.
The
necessity
extension
theoretical
models
careful
re-examination
those
use
emphasized.
Regarding
materials,
focus
on
dual-activated
probes
(LIR)
transition-metal-ion-activated
phosphors
both
lifetime
LIR
thermometry.
Several
particularly
important
applications
presented.
measurement
catalysis,
situ
mapping
microfluidics,
thermal
history
measurement,
at
extremely
high
temperatures,
fast
transient
low-pressure
via
upconversion
nanoparticle
emission
ratios,
evaluation
photothermal
chirality
noble
metal
clusters,
using
mobile
devices.
Routes
development
primary
view
redefinition
kelvin.
Abstract
Noninvasive
lanthanide‐doped
optical
thermometers
based
on
fluorescent
intensity
ratio
(FIR)
technique
have
emerged
as
promising
noncontact
tools
for
detecting
the
inaccessible
objects
at
different
scales.
Currently,
theoretical
and
experimental
investigations
of
various
influential
factors
thermal
performances
luminescence
become
one
hotspots
to
develop
highly
sensitive
thermometers.
On
other
hand,
near‐infrared
(NIR)
light‐responsive
nanothermometers
with
deep‐tissue
penetration
been
widely
applied
subcutaneous
intracellular
thermometry,
which
could
be
integrated
heating
imaging
functions
construct
all‐in‐one
thermometer‐heater
platforms
cancer
diagnosis
therapy.
In
this
review,
recent
advances
in
thermometry
thermally
coupled
levels
(TCLs)
are
elaborately
introduced
from
fundamental
aspects
possible
biomedical
applications,
perspective
outlook
emerging
challenges
FIR
science.
Advanced Materials,
Journal Year:
2023,
Volume and Issue:
35(36)
Published: July 21, 2023
Abstract
Luminescence
(nano)thermometry
is
a
remote
sensing
technique
that
relies
on
the
temperature
dependency
of
luminescence
features
(e.g.,
bandshape,
peak
energy
or
intensity,
and
excited
state
lifetimes
risetimes)
phosphor
to
measure
temperature.
This
provides
precise
thermal
readouts
with
superior
spatial
resolution
in
short
acquisition
times.
Although
thermometry
just
starting
become
more
mature
subject,
it
exhibits
enormous
potential
several
areas,
e.g.,
optoelectronics,
photonics,
micro‐
nanofluidics,
nanomedicine.
work
reviews
latest
trends
field,
including
establishment
comprehensive
theoretical
background
standardized
practices.
The
reliability,
repeatability,
reproducibility
are
also
discussed,
along
use
multiparametric
analysis
artificial‐intelligence
algorithms
enhance
readouts.
In
addition,
examples
provided
underscore
challenges
faces,
alongside
need
for
continuous
search
design
new
materials,
experimental
techniques,
procedures
improve
competitiveness,
accessibility,
popularity
technology
