Materials Today Chemistry, Journal Year: 2023, Volume and Issue: 30, P. 101559 - 101559
Published: May 4, 2023
Language: Английский
International Journal of Biological Macromolecules, Journal Year: 2022, Volume and Issue: 218, P. 930 - 968
Published: July 24, 2022
Language: Английский
Citations
266
International Journal of Molecular Sciences, Journal Year: 2022, Volume and Issue: 23(9), P. 4486 - 4486
Published: April 19, 2022
Alginate is an excellent biodegradable and renewable material that already used for a broad range of industrial applications, including advanced fields, such as biomedicine bioengineering, due to its biocompatible properties. This biopolymer can be produced from brown algae or microorganism culture. review presents the principles, chemical structures, gelation properties, interactions, production, sterilization, purification, types, alginate-based hydrogels developed so far. We present all strategies remarkably enhance this biopolymer’s physicochemical biological characteristics in various forms, injectable gels, fibers, films, hydrogels, scaffolds. Thus, we here engineering enhancement approaches achieved far terms mechanical reinforcement, thermal electrical performance, wettability, water sorption diffusion, antimicrobial activity, vivo vitro behavior, toxicity, cell adhesion, proliferation, differentiation, immunological response, biodegradation, porosity, use scaffolds tissue applications. These improvements overcome drawbacks alginate could exponentially increase significant number applications go paper industry bioprinting organs.
Language: Английский
Citations
116
MedComm, Journal Year: 2022, Volume and Issue: 4(1)
Published: Dec. 24, 2022
Abstract 3D bioprinting or additive manufacturing is an emerging innovative technology revolutionizing the field of biomedical applications by combining engineering, manufacturing, art, education, and medicine. This process involved incorporating cells with biocompatible materials to design required tissue organ model in situ for various vivo applications. Conventional printing constructing without any living components, thereby limiting its use several recent biological However, this uses additional complexities, including material choice, cell types, their growth differentiation factors. state‐of‐the‐art consciously summarizes different methods used importance setbacks. It also elaborates on concept bioinks utility. Biomedical such as cancer therapy, bone regeneration, wound healing involving have gained much attention years. article aims provide a comprehensive review all aspects associated bioprinting, from selection, technology, fabrication fields. Attempts been made highlight each element detail, along available reports literature. focuses providing single platform engineering field.
Language: Английский
Citations
95
Pharmaceutics, Journal Year: 2023, Volume and Issue: 15(3), P. 970 - 970
Published: March 17, 2023
Chronic wounds are a major concern for global health, affecting millions of individuals worldwide. As their occurrence is correlated with age and age-related comorbidities, incidence in the population set to increase forthcoming years. This burden further worsened by rise antimicrobial resistance (AMR), which causes wound infections that increasingly hard treat current antibiotics. Antimicrobial bionanocomposites an emerging class materials combine biocompatibility tissue-mimicking properties biomacromolecules activity metal or oxide nanoparticles. Among these nanostructured agents, zinc (ZnO) one most promising its microbicidal effects anti-inflammatory properties, as source essential ions. review analyses recent developments field nano-ZnO–bionanocomposite (nZnO-BNC) materials—mainly form films, but also hydrogel electrospun bandages—from different preparation techniques antibacterial wound-healing performances. The effect ZnO on mechanical, water gas barrier, swelling, optical, thermal, affinity, drug-release examined linked methods. assays over wide range bacterial strains extensively surveyed, studies finally considered provide comprehensive assessment framework. While early results promising, systematic standardised testing procedure comparison still lacking, partly because not-yet fully understood mechanism. work, therefore, allowed, hand, determination best strategies design, engineering, application n-ZnO-BNC, and, other identification challenges opportunities future research.
Language: Английский
Citations
86
Advanced Materials Interfaces, Journal Year: 2022, Volume and Issue: 10(2)
Published: Nov. 30, 2022
Abstract Hydrogels have been employed for water purification applications, but their performance and strength are unsatisfactory widespread adoption. Recently, hydrogel nanocomposites proposed to resolve the inherent challenges faced by hydrogels treatment. This review comprehensively analyzes treatment using adsorbent photocatalysis techniques. The structure, classification, tunable synthesis methods of explained. Further, how can be incorporated with functional nanoparticles (NPs) used as templates/precursors developing advanced 3D architectures, including formation nanocomposite beads printing objects discussed. Finally, structure‐property relationships critically reviewed considering introductory gelation chemistry, such swelling characteristics, mechanical properties, stimuli‐responsiveness, ionic/electronic conduction. extensive cross‐linking polymer chains NPs offers high mass/charge transport, surface areas, enhanced polymer‐water interactions achieve high‐performing adsorbents photocatalysts. Several motivating examples emerging NP‐containing use in Such efforts validated excellent technological potential held applications. future directions sustainable proposed.
Language: Английский
Citations
80
Advanced Science, Journal Year: 2023, Volume and Issue: 10(17)
Published: April 19, 2023
Chronic wounds in diabetic patients are challenging because their prolonged inflammation makes healing difficult, thus burdening patients, society, and health care systems. Customized dressing materials needed to effectively treat such that vary shape depth. The continuous development of 3D-printing technology along with artificial intelligence has increased the precision, versatility, compatibility various materials, providing considerable potential meet abovementioned needs. Herein, functional inks comprising DNA from salmon sperm DNA-induced biosilica inspired by marine sponges, developed for machine learning-based wound dressings. biomineralized silica incorporated into hydrogel a fast, facile manner. 3D-printed generates provided appropriate porosity, characterized effective exudate blood absorption at sites, mechanical tunability indicated good fidelity printability during optimized 3D printing. Moreover, act as nanotherapeutics, enhancing biological activity dressings terms reactive oxygen species scavenging, angiogenesis, anti-inflammation activity, thereby accelerating acute healing. These bioinspired hydrogels produce using biomineralization strategy an excellent platform clinical applications chronic repair.
Language: Английский
Citations
78
Materials Today Electronics, Journal Year: 2023, Volume and Issue: 5, P. 100055 - 100055
Published: Aug. 11, 2023
As personal portable devices, wearable sensors supply a leading-edge pathway to diagnose various diseases through actuating biological, physical, and chemical sensing capabilities. This could be commonly carried out via recording continuous real-time of the patient's physiological statuses, as well pathophysiological information. Although sensor technology is in infancy stage, tremendous attempts have been devoted approaching flexible polymeric sensors. Among polymer candidates applicable for synthesizing sensors, bio-based ones piqued more interest due their biocompatibility, biodegradability, eco-friendly features, cost-effectiveness. Additionally, several fabrication techniques professed architect efficient frameworks, such films, hydrogels, aerogels, ferrogels, 3D layers, electrospun mats, textiles. In this review, different mechanisms declared engineer are overviewed. Then, regarding advantages observed polymers, focused studies on natural-based described. Notably, cellulose, chitosan, silk, gelatin, alginate's role functionality highlighted. Accordingly, review has opened new window ahead opportunities based natural polymers. It hoped that generation will launched by combining emerging achievements obtained from employing sustainable green elements miniaturized structures.
Language: Английский
Citations
71
Giant, Journal Year: 2023, Volume and Issue: 17, P. 100209 - 100209
Published: Nov. 15, 2023
Additive manufacturing (AM) aka three-dimensional (3D) printing has been a well-established and unparalleled technology, which is expanding the boundaries of materials science exhibiting an enormous potential to fabricate intricate geometries for healthcare, electronics, construction sectors. In contemporary era, combination AM technology stimuli-responsive hydrogels (SRHs) helps create dynamic functional structures with extreme accuracy, are capable changing their shape, functional, or mechanical properties in response environmental cues such as humidity, heat, light, pH, magnetic field, electric etc. 3D SRHs permits creation on-demand dynamically controllable shapes excellent control over various self-repair, self-assembly, multi-functionality, These accelerate researchers think unthinkable applications. Additively manufactured objects have shown applications like tissue engineering, drug delivery, soft robots, sensors, other biomedical devices. The current review provides recent progress SRHs, more focus on techniques, stimuli mechanisms, shape morphing behaviors, Finally, trends future roadmap additively smart different also presented, will be helpful research. This holds great promise providing fundamental knowledge about diverse
Language: Английский
Citations
71
Carbohydrate Polymers, Journal Year: 2022, Volume and Issue: 296, P. 119964 - 119964
Published: Aug. 5, 2022
Language: Английский
Citations
70
RSC Advances, Journal Year: 2023, Volume and Issue: 13(50), P. 35251 - 35291
Published: Jan. 1, 2023
Nanocomposite hydrogel biomaterials represent an exciting frontier in biomedicine, offering solutions to longstanding challenges.
Language: Английский
Citations
70