Combining patient-lesion and big data approaches to reveal hippocampal contributions to spatial memory and navigation DOI Creative Commons
Sara Pishdadian, Antoine Coutrot,

Lauren Webber

et al.

iScience, Journal Year: 2024, Volume and Issue: 27(6), P. 109977 - 109977

Published: May 14, 2024

Language: Английский

Prolonged sleep deprivation induces a cytokine-storm-like syndrome in mammals DOI Creative Commons
Di Sang,

Keteng Lin,

Yini Yang

et al.

Cell, Journal Year: 2023, Volume and Issue: 186(25), P. 5500 - 5516.e21

Published: Nov. 27, 2023

Language: Английский

Citations

75

Country differences in nocturnal sleep variability: Observations from a large-scale, long-term sleep wearable study DOI Creative Commons
Adrian R. Willoughby,

Iman Alikhani,

Mari Karsikas

et al.

Sleep Medicine, Journal Year: 2023, Volume and Issue: 110, P. 155 - 165

Published: Aug. 10, 2023

Country or regional differences in sleep duration are well-known, but few large-scale studies have specifically evaluated variability, either across the work week, terms of weekday and weekend sleep. Sleep measures obtained over 50 million night's sleep, from ∼220,000 wearable device users 35 countries were analysed. Each person contributed an average ∼242 nights data. Multiple regression was used to assess impact country residence had on a duration, timing, efficiency, extension social jetlag. Nocturnal shorter later onset Asia than other regions. Despite this, efficiency lower higher. Weekend longer Europe USA Asia, only partially related duration. There also cross-country jetlag although less distinct for extension. In addition variability suggest that using latter as indicator debt may need be reconsidered. exhibiting both short high culturally different means coping with inadequate is likely. region culture, particularly those work, merit closer examination factors influencing normative patterns around world.

Language: Английский

Citations

60

Longitudinal Sleep Patterns and Cognitive Impairment in Older Adults DOI Creative Commons
Samantha Keil, Abigail G. Schindler,

Marie X. Wang

et al.

JAMA Network Open, Journal Year: 2023, Volume and Issue: 6(12), P. e2346006 - e2346006

Published: Dec. 4, 2023

Importance Sleep disturbances and clinical sleep disorders are associated with all-cause dementia neurodegenerative conditions, but it remains unclear how longitudinal changes in impact the incidence of cognitive impairment. Objective To evaluate association patterns age-related function healthy older adults. Design, Setting, Participants This cross-sectional study is a retrospective analyses Seattle Longitudinal Study (SLS), which evaluated self-reported duration (1993-2012) performance (1997-2020) within SLS were enrolled as part community-based cohort from Group Health Cooperative Puget Sound Maintenance Organization Washington between 1956 2020. Data analysis was performed September 2020 to May 2023. Main Outcomes Measures The main outcome for this impairment, defined by subthreshold on both Mini-Mental State Examination Mattis Dementia Rating Scale. self-report median nightly over last week assessed longitudinally multiple time points. Median duration, phenotype (short sleep, ≤7 hours; medium = 7 hour; long ≥7 hours), change (slope), variability (SD or variability) evaluated. Results Of participants SLS, only 1104 who administered Behavior Questionnaire neuropsychologic battery included study. A total 826 individuals (mean [SD] age, 76.3 [11.8] years; 468 women [56.7%]; 217 apolipoprotein E ε4 allele carriers [26.3%]) had complete demographic information Analysis using Cox proportional hazard regression model (concordance, 0.76) showed that status short sleeper (hazard ratio, 3.67; 95% CI, 1.59-8.50) higher 3.06; 1.14-5.49) significantly Conclusions Relevance In performance, impaired performance. Furthermore, high highlighting possibility instability periods may decline

Language: Английский

Citations

26

Individual sleep need is flexible and dynamically related to cognitive function DOI
Anders M. Fjell, Kristine B. Walhovd

Nature Human Behaviour, Journal Year: 2024, Volume and Issue: 8(3), P. 422 - 430

Published: Feb. 20, 2024

Language: Английский

Citations

12

Short sleep and insomnia are associated with accelerated epigenetic age DOI
Cynthia Kusters, Eric T. Klopack, Eileen M. Crimmins

et al.

Psychosomatic Medicine, Journal Year: 2023, Volume and Issue: 86(5), P. 453 - 462

Published: Aug. 18, 2023

Short sleep and insomnia are each associated with a greater risk of age-related disease, which suggests that insufficient may accelerate biological aging. We examine whether short alone or together relates to epigenetic age among older adults.

Language: Английский

Citations

20

Wayfinding across ocean and tundra: what traditional cultures teach us about navigation DOI Creative Commons

Pablo Fernandez-Velasco,

Hugo J. Spiers

Trends in Cognitive Sciences, Journal Year: 2023, Volume and Issue: 28(1), P. 56 - 71

Published: Oct. 3, 2023

Research on human navigation by psychologists and neuroscientists has come mainly from a limited range of environments participants inhabiting western countries. By contrast, numerous anthropological accounts illustrate the diverse ways in which cultures adapt to their surrounding environment navigate. Here, we provide an overview these studies relate them cognitive science research. The diversity cues traditional is much higher multimodal compared with experiments laboratory. It typically involves integrated system methods, drawing detailed understanding environmental cues, specific tools, forms part broader cultural system. We highlight recent methodological developments for measuring skill modelling behaviour that will aid future research into how culture shape navigation.

Language: Английский

Citations

20

Entropy and a sub-group of geometric measures of paths predict the navigability of an environment DOI Creative Commons
Demet Yeşiltepe, Pablo Fernández Velasco, Antoine Coutrot

et al.

Cognition, Journal Year: 2023, Volume and Issue: 236, P. 105443 - 105443

Published: March 29, 2023

Language: Английский

Citations

19

The relationship between object-based spatial ability and virtual navigation performance DOI Creative Commons
Tanya Garg, Pablo Fernández Velasco, Eva Zita Patai

et al.

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(5), P. e0298116 - e0298116

Published: May 9, 2024

Spatial navigation is a multi-faceted behaviour drawing on many different aspects of cognition. Visuospatial abilities, such as mental rotation and visuospatial working memory, in particular, may be key factors. A range tests have been developed to assess processing but how relate ability remains unclear. This understanding important advance for disease monitoring various disorders (e.g., Alzheimer’s disease) where spatial impairment an early symptom. Here, we report the use established mobile gaming app, Sea Hero Quest (SHQ), measure sample young, predominantly female university students (N = 78; 20; 74.3%; mean age 20.33 years). We used three separate embedded SHQ: wayfinding, path integration memory radial arm maze. In same participants, also collected measures (Mental Rotation Test), (Design Organization Test) (Digital Corsi). found few strong correlations across our measures. Being good at wayfinding virtual test does not individual will integration, superior maze, or rate themself having sense direction. However, observed that participants who were task SHQ tended perform well tasks examined here, landmark strategy maze task. These findings help clarify associations between abilities involved navigation.

Language: Английский

Citations

8

No phenotypic or genotypic evidence for a link between sleep duration and brain atrophy DOI Creative Commons
Anders M. Fjell, Øystein Sørensen, Yunpeng Wang

et al.

Nature Human Behaviour, Journal Year: 2023, Volume and Issue: 7(11), P. 2008 - 2022

Published: Oct. 5, 2023

Abstract Short sleep is held to cause poorer brain health, but short associated with higher rates of structural decline? Analysing 8,153 longitudinal MRIs from 3,893 healthy adults, we found no evidence for an association between duration and atrophy. In contrast, cross-sectional analyses (51,295 observations) showed inverse U-shaped relationships, where a 6.5 (95% confidence interval, (5.7, 7.3)) hours was the thickest cortex largest volumes relative intracranial volume. This fits converging research on mortality, health cognition that points roughly seven being good health. Genome-wide suggested genes longer below-average sleepers were linked shorter above-average sleepers. Mendelian randomization did not yield causal impacts structure. The combined results challenge notion habitual causes atrophy, suggesting normal brains promote adequate duration—which than current recommendations.

Language: Английский

Citations

14

Video gaming, but not reliance on GPS, is associated with spatial navigation performance DOI Creative Commons
Emre Yavuz, Chuanxiuyue He, Christoffer J. Gahnstrom

et al.

Journal of Environmental Psychology, Journal Year: 2024, Volume and Issue: 96, P. 102296 - 102296

Published: April 22, 2024

Recent evidence suggests that greater reliance on GPS-assisted devices is associated with poorer navigation ability. Studies have also shown video gaming may be We investigated the effect of game experience and GPS ability using mobile app Sea Hero Quest, which has been to predict real-world wayfinding performance. tested a group US-based participants' performance (n = 822, 367 men, 455 women, mean age 26.3 years, range 18-52 years) asked them series questions relating experience. A multiple linear regression model found no significant association between There was weekly hours These findings provide platform for future intervention-based research studies investigating whether daily activities causally enhance or disrupt specific cognitive abilities.

Language: Английский

Citations

5