Effective Personalization of Stereotactic Radiosurgery for Brain Metastases in the Modern Era DOI
Donna M. Edwards, Michelle M. Kim

The Cancer Journal, Journal Year: 2024, Volume and Issue: 30(6), P. 393 - 400

Published: Nov. 1, 2024

As survival rates improve for patients with metastatic disease, more are requiring complex treatment brain metastases. Stereotactic radiosurgery (SRS) is a conformal radiotherapy technique that allows high ablative dose to be delivered specific target and standard effective local therapy the of limited This review highlights current landscape SRS in context modern therapeutic advances identifies new research frontiers personalize maximize ratio.

Language: Английский

Low‐Dimensional Structure Modulation in Ag8SnSe6 for Enhanced Thermoelectric Performance DOI Open Access
Xueke Zhao, Mengyao Li, Mochen Jia

et al.

Advanced Functional Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 15, 2025

Abstract Ternary liquid‐like thermoelectric materials have garnered significant attention due to their ultra‐low lattice thermal conductivity. Among these, Ag 8 SnSe 6 stands out for its exceptionally low sound velocity and However, the inherent poor electrical conductivity suboptimal properties of necessitate further improvement. Here, a novel approach is initiated enhance by combining low‐dimensionalization with intrinsic doping. For first time, this work successfully synthesizes single‐phase nanocrystals, ≈10 nm in size, correct phase composition using robust reliable colloidal method. This represents improvement over previous reports on material. Reducing crystal domains nanoscale induces quantum confinement effects, increasing density states near Fermi surface. It also introduces additional grain boundaries, which lower simplify structural design. Moreover, incorporating small amounts Sn nanopowder into nanocrystals before consolidation enhances performance. acts as donor dopant, electronic concentration while at same time improving mobility reducing interface barriers, thus significantly material transport properties. Additionally, presence leads formation point defects, dislocations, secondary phases, increase phonon scattering reduce Through synergistic optimization, figure merit shows across wide temperature range. Overall, strategy presented controlled preparation decoupling transport, practical application single‐leg modules.

Language: Английский

Citations

1

Development and routine implementation of deep learning algorithm for automatic brain metastases segmentation on MRI for RANO-BM criteria follow-up DOI Creative Commons

Loïse Dessoude,

Raphaëlle Lemaire,

Roger Y. Andres

et al.

NeuroImage, Journal Year: 2025, Volume and Issue: 306, P. 121002 - 121002

Published: Jan. 10, 2025

The RANO-BM criteria, which employ a one-dimensional measurement of the largest diameter, are imperfect due to fact that lesion volume is neither isotropic nor homogeneous. Furthermore, this approach inherently time-consuming. Consequently, in clinical practice, monitoring patients trials compliance with criteria rarely achieved. objective study was develop and validate an AI solution capable delineating brain metastases (BM) on MRI easily obtain, using in-house solution, as well BM routine setting. A total 27,456 post-Gadolinium-T1 from 132 were employed study. deep learning (DL) model constructed PyTorch Lightning frameworks, UNETR transfer method segment MRI. visual analysis results demonstrates confident delineation lesions. shows 100 % accuracy predicting comparison expert medical doctor. There high degree overlap between doctor's segmentation, mean DICE score 0.77. diameter lesions found be concordant reference segmentation. user interface developed can readily provide following accessible everyone without expertise offers effective segmentation substantial time savings.

Language: Английский

Citations

0

Stereotactic radiosurgery for patients with brain metastases: current principles, expanding indications and opportunities for multidisciplinary care DOI
Alireza Mansouri, Ahmad Ozair, Debarati Bhanja

et al.

Nature Reviews Clinical Oncology, Journal Year: 2025, Volume and Issue: unknown

Published: March 19, 2025

Language: Английский

Citations

0

Impact of brain metastasis size at the time of radiotherapy on local control and radiation necrosis DOI
Narmeen S Rashid,

Nayan Lamba,

Paul J. Catalano

et al.

Journal of Neuro-Oncology, Journal Year: 2025, Volume and Issue: unknown

Published: April 15, 2025

Language: Английский

Citations

0

Stereotactic Radiosurgery for Intracranial Breast Metastases: A Systematic Review and Meta-Analysis DOI Open Access
Neil D. Almeida, Cathleen C. Kuo, Tyler V. Schrand

et al.

Cancers, Journal Year: 2024, Volume and Issue: 16(20), P. 3551 - 3551

Published: Oct. 21, 2024

To determine the impact of stereotactic radiosurgery on outcomes metastatic breast cancer with intracranial metastases.

Language: Английский

Citations

1

Association between tumor location and toxicity outcomes after stereotactic radiosurgery for brain metastases DOI
Boya Wang, Alexandra Bukowski, Orit Kaidar‐Person

et al.

Journal of Neuro-Oncology, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 15, 2024

Language: Английский

Citations

1

Effective Personalization of Stereotactic Radiosurgery for Brain Metastases in the Modern Era DOI
Donna M. Edwards, Michelle M. Kim

The Cancer Journal, Journal Year: 2024, Volume and Issue: 30(6), P. 393 - 400

Published: Nov. 1, 2024

As survival rates improve for patients with metastatic disease, more are requiring complex treatment brain metastases. Stereotactic radiosurgery (SRS) is a conformal radiotherapy technique that allows high ablative dose to be delivered specific target and standard effective local therapy the of limited This review highlights current landscape SRS in context modern therapeutic advances identifies new research frontiers personalize maximize ratio.

Language: Английский

Citations

1