Microsystems & Nanoengineering,
Journal Year:
2021,
Volume and Issue:
7(1)
Published: Aug. 13, 2021
Abstract
Implantable
deep
brain
stimulation
(DBS)
systems
are
utilized
for
clinical
treatment
of
diseases
such
as
Parkinson’s
disease
and
chronic
pain.
However,
long-term
efficacy
DBS
is
limited,
neuroplastic
changes
associated
therapeutic
mechanisms
not
well
understood.
Fundamental
mechanistic
investigation,
typically
accomplished
in
small
animal
models,
difficult
because
the
need
stimulators
that
currently
require
either
frequent
handling
test
subjects
to
charge
battery-powered
or
specialized
setups
manage
tethers
restrict
experimental
paradigms
compromise
insight.
To
overcome
these
challenges,
we
demonstrate
a
fully
implantable,
wireless,
battery-free
platform
allows
rodents
with
capability
control
parameters
digitally
real
time.
The
devices
able
provide
over
wide
range
frequencies
biphasic
pulses
constant
voltage
via
low-impedance,
surface-engineered
platinum
electrodes.
utilize
off-the-shelf
components
feature
ability
customize
electrodes
enable
broad
utility
rapid
dissemination.
Efficacy
system
demonstrated
readout
stimulation-evoked
neural
activity
vivo
medial
forebrain
bundle
freely
moving
rats
evoke
characteristic
head
motion
36
days.
Advanced Materials,
Journal Year:
2021,
Volume and Issue:
34(16)
Published: Dec. 12, 2021
Abstract
Medical
robots
are
invaluable
players
in
non‐pharmaceutical
treatment
of
disabilities.
Particularly,
using
prosthetic
and
rehabilitation
devices
with
human–machine
interfaces
can
greatly
improve
the
quality
life
for
impaired
patients.
In
recent
years,
flexible
electronic
soft
robotics
have
attracted
tremendous
attention
this
field
due
to
their
high
biocompatibility,
functionality,
conformability,
low‐cost.
Flexible
on
will
make
a
promising
alternative
conventional
rigid
devices,
which
potentially
revolutionize
paradigm
future
direction
medical
terms
feedback
user
experience.
review,
fundamental
components
materials,
structures,
mechanisms
human‐machine
summarized
by
renowned
applications
five
primary
areas:
physical
chemical
sensing,
physiological
recording,
information
processing
communication,
robotic
actuation,
stimulation.
This
review
further
concludes
discussing
outlook
current
challenges
these
technologies
as
interface
robotics.
Advanced Intelligent Systems,
Journal Year:
2022,
Volume and Issue:
4(7)
Published: March 29, 2022
With
the
development
of
5G
and
Internet
Things
(IoT),
era
big
data‐driven
product
design
is
booming.
In
addition,
artificial
intelligence
(AI)
also
emerging
evolving
by
recent
breakthroughs
in
computing
power
software
architectures.
this
regard,
digital
twin,
analyzing
various
sensor
data
with
help
AI
algorithms,
has
become
a
cutting‐edge
technology
that
connects
physical
virtual
worlds,
which
sensors
are
highly
desirable
to
collect
environmental
information.
However,
although
existing
technologies,
including
cameras,
microphones,
inertial
measurement
units,
etc.,
widely
used
as
sensing
elements
for
applications,
high‐power
consumption
battery
replacement
them
still
problem.
Triboelectric
nanogenerators
(TENGs)
self‐powered
supply
feasible
platform
realizing
self‐sustainable
low‐power
systems.
Herein,
progress
on
TENG‐based
intelligent
systems,
is,
wearable
electronics,
robot‐related
smart
homes,
followed
prospective
future
enabled
fusion
technology,
focused
on.
Finally,
how
apply
systems
IoT
discussed.
Advanced Materials,
Journal Year:
2021,
Volume and Issue:
34(5)
Published: Nov. 16, 2021
The
ongoing
miniaturization
of
devices
and
development
wireless
implantable
technologies
demand
electromagnetic
interference
(EMI)-shielding
materials
with
customizability.
Additive
manufacturing
conductive
polymer
hydrogels
favorable
conductivity
biocompatibility
can
offer
new
opportunities
for
EMI-shielding
applications.
However,
simultaneously
achieving
high
conductivity,
design
freedom,
shape
fidelity
in
3D
printing
is
still
very
challenging.
Here,
an
aqueous
Ti3
C2
-MXene-functionalized
poly(3,4-ethylenedioxythiophene):polystyrene
sulfonate
ink
developed
extrusion
to
create
objects
arbitrary
geometries,
a
freeze-thawing
protocol
proposed
transform
the
printed
directly
into
highly
robust
on
both
macro-
microscale.
as-obtained
hydrogel
exhibits
1525.8
S
m-1
at
water
content
up
96.6
wt%
also
satisfactory
mechanical
properties
flexibility,
stretchability,
fatigue
resistance.
Furthermore,
use
customizable
applications
demonstrated.
easy-to-manufacture
approach,
along
highlighted
superior
properties,
expands
potential
future
represents
real
breakthrough
from
current
state
art.
Nature Communications,
Journal Year:
2022,
Volume and Issue:
13(1)
Published: June 9, 2022
Wireless
technologies-supported
printed
flexible
electronics
are
crucial
for
the
Internet
of
Things
(IoTs),
human-machine
interaction,
wearable
and
biomedical
applications.
However,
challenges
to
existing
printing
approaches
remain,
such
as
low
precision,
difficulty
in
conformal
printing,
complex
ink
formulations
processes.
Here
we
present
a
room-temperature
direct
strategy
wireless
electronics,
where
distinct
high-performance
functional
modules
(e.g.,
antennas,
micro-supercapacitors,
sensors)
can
be
fabricated
with
high
resolution
further
integrated
on
various
flat/curved
substrates.
The
additive-free
titanium
carbide
(Ti3C2Tx)
MXene
aqueous
inks
regulated
large
single-layer
ratio
(>90%)
narrow
flake
size
distribution,
offering
metallic
conductivity
(~6,
900
S
cm-1)
ultrafine-printed
tracks
(3
μm
line
gap
0.43%
spatial
uniformity)
without
annealing.
In
particular,
build
an
all-MXene-printed
system
capable
communication,
energy
harvesting,
smart
sensing.
This
work
opens
door
high-precision
additive
manufacturing
at
room
temperature.
ACS Nano,
Journal Year:
2023,
Volume and Issue:
17(3), P. 1764 - 1802
Published: Jan. 30, 2023
The
advent
of
5G
and
the
Internet
Things
has
spawned
a
demand
for
wearable
electronic
devices.
However,
lack
suitable
flexible
energy
storage
system
become
"Achilles'
Heel"
Additional
problems
during
transformation
battery
structure
from
conventional
to
also
present
severe
challenge
design.
Flexible
Zn-based
batteries,
including
Zn-ion
batteries
Zn–air
have
long
been
considered
promising
candidates
due
their
high
safety,
eco-efficiency,
substantial
reserve,
low
cost.
In
past
decade,
researchers
come
up
with
elaborate
designs
each
portion
improve
ionic
conductivities,
mechanical
properties,
environment
adaptabilities,
scalable
productions.
It
would
be
helpful
summarize
reported
strategies
compare
pros
cons
facilitate
further
research
toward
commercialization
batteries.
this
review,
current
progress
in
developing
is
comprehensively
reviewed,
electrolytes,
cathodes,
anodes,
discussed
terms
synthesis,
characterization,
performance
validation.
By
clarifying
challenges
design,
we
methodology
previous
investigations
propose
future
development.
end,
paradigm
summarized
fit
burgeoning
requirement
devices
an
iterative
process,
which
will
benefit
development
Science Advances,
Journal Year:
2022,
Volume and Issue:
8(15)
Published: April 15, 2022
Supplying
wireless
power
is
a
challenging
technical
problem
of
great
importance
for
implantable
biomedical
devices.
Here,
we
introduce
novel
piezoelectric
ultrasound
energy–harvesting
device
based
on
Sm-doped
Pb(Mg
1/3
Nb
2/3
)O
3
-PbTiO
(Sm-PMN-PT)
single
crystal.
The
output
density
this
can
reach
up
to
1.1
W/cm
2
in
vitro,
which
18
times
higher
than
the
previous
record
(60
mW/cm
).
After
being
implanted
rat
brain,
under
1-MHz
with
safe
intensity
212
,
as-developed
produce
an
instantaneous
effective
280
μW,
immediately
activate
periaqueductal
gray
brain
area.
electrophysiological
experiments
anesthesia
and
behavioral
demonstrate
that
our
wireless-powered
well
qualified
deep
stimulation
analgesia
applications.
These
encouraging
results
provide
new
insights
into
development
devices
future.
Nature Communications,
Journal Year:
2022,
Volume and Issue:
13(1)
Published: July 4, 2022
Abstract
Electronic
visual
prostheses,
or
biomimetic
eyes,
have
shown
the
feasibility
of
restoring
functional
vision
in
blind
through
electrical
pulses
to
initiate
neural
responses
artificially.
However,
existing
prostheses
predominantly
use
wired
connections
electromagnetic
waves
for
powering
and
data
telemetry,
which
raises
safety
concerns
couples
inefficiently
miniaturized
implant
units.
Here,
we
present
a
flexible
ultrasound-induced
retinal
stimulating
piezo-array
that
can
offer
an
alternative
wireless
artificial
prosthesis
approach
evoking
percepts
individuals.
The
device
integrates
two-dimensional
with
32-pixel
electrodes
printed
circuit
board.
Each
piezo-element
be
ultrasonically
individually
activated,
thus,
spatially
reconfigurable
electronic
patterns
dynamically
applied
via
programmable
ultrasound
beamlines.
As
proof
concept,
demonstrate
pattern
reconstruction
ex
vivo
murine
tissue,
showing
potential
this
restore
functional,
life-enhancing
people
living
blindness.