3D Bioelectronics with a Remodellable Matrix for Long‐Term Tissue Integration and Recording DOI Creative Commons
Alexander J. Boys, Alejandro Carnicer‐Lombarte, Amparo Güemes

et al.

Advanced Materials, Journal Year: 2022, Volume and Issue: 35(8)

Published: Dec. 2, 2022

Abstract Bioelectronics hold the key for understanding and treating disease. However, achieving stable, long‐term interfaces between electronics body remains a challenge. Implantation of bioelectronic device typically initiates foreign response, which can limit recording stimulation efficacy. Techniques from regenerative medicine have shown high propensity promoting integration implants with surrounding tissue, but these lack capabilities sophisticated actuation afforded by electronics. Combining two fields achieve best both worlds. Here, construction hybrid implant system creating tissue is shown. Implants are created combining microelectrode array bioresorbable remodellable gel. These to produce minimal response when placed into musculature, allowing one record electromyographic signals spatial resolution. This platform drives possibility new generation implantable interfacing.

Language: Английский

Flexible Electronics and Devices as Human–Machine Interfaces for Medical Robotics DOI
Wenzheng Heng,

Samuel A. Solomon,

Wei Gao

et al.

Advanced Materials, Journal Year: 2021, Volume and Issue: 34(16)

Published: Dec. 12, 2021

Abstract Medical robots are invaluable players in non‐pharmaceutical treatment of disabilities. Particularly, using prosthetic and rehabilitation devices with human–machine interfaces can greatly improve the quality life for impaired patients. In recent years, flexible electronic soft robotics have attracted tremendous attention this field due to their high biocompatibility, functionality, conformability, low‐cost. Flexible on will make a promising alternative conventional rigid devices, which potentially revolutionize paradigm future direction medical terms feedback user experience. review, fundamental components materials, structures, mechanisms human‐machine summarized by renowned applications five primary areas: physical chemical sensing, physiological recording, information processing communication, robotic actuation, stimulation. This review further concludes discussing outlook current challenges these technologies as interface robotics.

Language: Английский

Citations

375

Artificial Intelligence (AI) and Internet of Medical Things (IoMT) Assisted Biomedical Systems for Intelligent Healthcare DOI Creative Commons
Pandiaraj Manickam, Siva Ananth Mariappan,

Sindhu Monica Murugesan

et al.

Biosensors, Journal Year: 2022, Volume and Issue: 12(8), P. 562 - 562

Published: July 25, 2022

Artificial intelligence (AI) is a modern approach based on computer science that develops programs and algorithms to make devices intelligent efficient for performing tasks usually require skilled human intelligence. AI involves various subsets, including machine learning (ML), deep (DL), conventional neural networks, fuzzy logic, speech recognition, with unique capabilities functionalities can improve the performances of medical sciences. Such systems simplify intervention in clinical diagnosis, imaging, decision-making ability. In same era, Internet Medical Things (IoMT) emerges as next-generation bio-analytical tool combines network-linked biomedical software application advancing health. this review, we discuss importance improving IoMT point-of-care (POC) used advanced healthcare sectors such cardiac measurement, cancer diabetes management. The role supporting robotic surgeries developed applications also discussed article. position functionality, detection accuracy, ability devices, evaluation associated risks assessment carefully critically review. This review encompasses technological engineering challenges prospects AI-based cloud-integrated personalized designing POC suitable healthcare.

Language: Английский

Citations

364

Artificial intelligence meets medical robotics DOI Open Access
Michael C. Yip, Septimiu E. Salcudean, Ken Goldberg

et al.

Science, Journal Year: 2023, Volume and Issue: 381(6654), P. 141 - 146

Published: July 13, 2023

Artificial intelligence (AI) applications in medical robots are bringing a new era to medicine. Advanced can perform diagnostic and surgical procedures, aid rehabilitation, provide symbiotic prosthetics replace limbs. The technology used these devices, including computer vision, image analysis, haptics, navigation, precise manipulation, machine learning (ML) , could allow autonomous carry out imaging, remote surgery, subtasks, or even entire procedures. Moreover, AI rehabilitation devices advanced individualized support, as well improved functionality mobility (see the figure). combination of extraordinary advances robotics, medicine, materials science, computing bring safer, more efficient, widely available patient care future. -Gemma K. Alderton.

Language: Английский

Citations

80

Wireless Technologies in Flexible and Wearable Sensing: From Materials Design, System Integration to Applications DOI

Lingyan Kong,

Weiwei Li,

Tinghao Zhang

et al.

Advanced Materials, Journal Year: 2024, Volume and Issue: 36(27)

Published: April 23, 2024

Wireless and wearable sensors attract considerable interest in personalized healthcare by providing a unique approach for remote, noncontact, continuous monitoring of various health-related signals without interference with daily life. Recent advances wireless technologies have promoted practical applications due to their significantly improved characteristics, such as reduction size thickness, enhancement flexibility stretchability, conformability the human body. Currently, most researches focus on active materials structural designs sensors, just few exceptions reflecting data transmission. This review provides comprehensive overview state-of-the-art related studies empowering sensors. The emerging functional nanomaterials utilized designing modules are highlighted, which include metals, carbons, MXenes. Additionally, outlines system-level integration flexible spanning from novel design strategies enhanced efficient transmitting wirelessly. Furthermore, introduces representative remote noninvasive physiological through on-skin implantable sensing systems. Finally, challenges, perspectives, unprecedented opportunities discussed.

Language: Английский

Citations

65

Stretchable surface electromyography electrode array patch for tendon location and muscle injury prevention DOI Creative Commons
Shuaijian Yang,

Jinhao Cheng,

Jin Shang

et al.

Nature Communications, Journal Year: 2023, Volume and Issue: 14(1)

Published: Oct. 14, 2023

Surface electromyography (sEMG) can provide multiplexed information about muscle performance. If current sEMG electrodes are stretchable, arrayed, and able to be used multiple times, they would offer adequate high-quality data for continuous monitoring. The lack of these properties delays the widespread use in clinics everyday life. Here, we address constraints by design an adhesive dry electrode using tannic acid, polyvinyl alcohol, PEDOT:PSS (TPP). TPP offers superior stretchability (~200%) adhesiveness (0.58 N/cm) compared electrodes, ensuring stable long-term contact with skin recording (>20 dB; >5 days). In addition, developed a metal-polymer array patch (MEAP) comprising liquid metal (LM) circuits electrodes. MEAP demonstrated better conformability than commercial arrays, resulting higher signal-to-noise ratio more recordings during movements. Manufactured scalable screen-printing, MEAPs feature completely stretchable material architecture, enabling real-time monitoring stress, fatigue, tendon displacement. Their potential reduce injuries enhance performance daily exercise professional sports holds great promise.

Language: Английский

Citations

56

Metaverse Wearables for Immersive Digital Healthcare: A Review DOI Creative Commons
Kisoo Kim,

Hyosill Yang,

Ji-Hun Lee

et al.

Advanced Science, Journal Year: 2023, Volume and Issue: 10(31)

Published: Sept. 22, 2023

The recent exponential growth of metaverse technology has been instrumental in reshaping a myriad sectors, not least digital healthcare. This comprehensive review critically examines the landscape and future applications wearables toward immersive key technologies advancements that have spearheaded metamorphosis are categorized, encapsulating all-encompassed extended reality, such as virtual augmented mixed other haptic feedback systems. Moreover, fundamentals their deployment assistive healthcare (especially for rehabilitation), medical nursing education, remote patient management treatment investigated. potential benefits integrating into paradigms multifold, encompassing improved prognosis, enhanced accessibility to high-quality care, high standards practitioner instruction. Nevertheless, these without inherent challenges untapped opportunities, which span privacy protection, data safeguarding, innovation artificial intelligence. In summary, research trajectories circumvent hurdles also discussed, further augmenting incorporation within infrastructures post-pandemic era.

Language: Английский

Citations

45

Shaping high-performance wearable robots for human motor and sensory reconstruction and enhancement DOI Creative Commons
Haisheng Xia, Yuchong Zhang, Nona Rajabi

et al.

Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)

Published: Feb. 26, 2024

Abstract Most wearable robots such as exoskeletons and prostheses can operate with dexterity, while wearers do not perceive them part of their bodies. In this perspective, we contend that integrating environmental, physiological, physical information through multi-modal fusion, incorporating human-in-the-loop control, utilizing neuromuscular interface, employing flexible electronics, acquiring processing human-robot biomechatronic chips, should all be leveraged towards building the next generation robots. These technologies could improve embodiment With optimizations in mechanical structure clinical training, better facilitate human motor sensory reconstruction enhancement.

Language: Английский

Citations

32

Wearable and Implantable Soft Robots DOI
Shukun Yin,

Dickson R. Yao,

Yu Song

et al.

Chemical Reviews, Journal Year: 2024, Volume and Issue: 124(20), P. 11585 - 11636

Published: Oct. 11, 2024

Soft robotics presents innovative solutions across different scales. The flexibility and mechanical characteristics of soft robots make them particularly appealing for wearable implantable applications. scale level invasiveness required depend on the extent human interaction. This review provides a comprehensive overview robots, including applications in rehabilitation, assistance, organ simulation, surgical tools, therapy. We discuss challenges such as complexity fabrication processes, integration responsive materials, need robust control strategies, while focusing advances actuation sensing mechanisms, techniques. Finally, we future outlook, highlighting key proposing potential solutions.

Language: Английский

Citations

16

Highly Flexible, Stretchable, and Compressible Lignin‐Based Hydrogel Sensors with Frost Resistance for Advanced Bionic Hand Control DOI Open Access
Jian Yang, Kang Yang, Xingye An

et al.

Advanced Functional Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 7, 2025

Abstract Bio‐based hydrogels, valued for their flexibility, tunable mechanical properties, and biocompatibility, are promising materials wearable skins sensing devices in bionic hand control systems. Lignin, a biopolymer rich functional groups, can be modified into UV‐curable monomers, enabling the development of 3D‐printed hydrogels via photopolymerization. However, inherent rigidity lignin's aromatic rings, coupled with covalent cross‐linking between lignin other often limits hydrogel's stretchability (poor strain) compressibility. Additional challenges, including poor moisture retention freeze resistance, further hinder wider application. In this study, lignin‐based hydrogel is developed high tensile strain (≥350%), compressive (≈95%), fatigue resistance (up to 10 000 cycles under 50% strain, 200–800 95% strain), which achieved by incorporating glycerol lithium chloride facilitate dynamic hydrogen ion bonds, while accordingly reducing sites monomers. The enhanced allow effective performance at −40±1 °C. Afterward, using 3D printing technology, sensors ripple‐shaped 3 × Matrix pressure fabricated, demonstrated uniform stress distribution improved controlling complex movements, underscoring application advancing human–machine interfaces.

Language: Английский

Citations

4

A lightweight prosthetic hand with 19-DOF dexterity and human-level functions DOI Creative Commons
Hao Yang,

Zhe Tao,

Jian Yang

et al.

Nature Communications, Journal Year: 2025, Volume and Issue: 16(1)

Published: Jan. 22, 2025

A human hand has 23-degree-of-freedom (DOF) dexterity for managing activities of daily living (ADLs). Current prosthetic hands, primarily driven by motors or pneumatic actuators, fall short in replicating human-level functions, due to limited DOF. Here, we develop a lightweight that possesses biomimetic 19-DOF integrating 38 shape-memory alloy (SMA) actuators precisely control five fingers and the wrist. The features real-time sensing joint angles each finger, feeding data into module selectively heating cooling SMA closed-loop manner, mimicking functioning muscles. Enabled high-power density SMAs, part (from wrist fingertip) only weighs 0.22 kg, much lower than existing products. We also integrate an onboard power management provides electricity operating entire system. In addition 33 standard grasping modes, this supports 6 advanced modes designed enhanced evaluation, expanding range achievable ADLs amputees while facilitating prosthesis function tests validation real-world scenarios. This innovation offers significant advancement promising improved quality life users. Traditional hands have degrees freedom (DOFs) restricted modes. authors (370 g) with shape memory actuators.

Language: Английский

Citations

3