A mathematical model for simulating photoacoustic signal generation and propagation in biological tissues DOI Creative Commons
Mohammed Tarek GadAllah, Abd El–Naser A. Mohamed,

Alaa A. Hefnawy

et al.

Optical and Quantum Electronics, Journal Year: 2023, Volume and Issue: 56(1)

Published: Nov. 23, 2023

Abstract Photoacoustic (PA) medical imaging is a crossbred technique relying on light-induced ultrasonic waves due to the PA effect phenomenon recorded primarily in 1880 by A. G. Bell. Numerical simulation, also known as in-silico, studies assist scientists minimizing incorrect experiments both in-vitro and in-vivo. modeling techniques help achieve fast simulation process contrast pure mathematics alone. However, if suitable facilitated mathematical model can be established prior applying numerical modeling, it will of great interest whole numeric model. Numerous equations, theorems, propositions have been proposed signal generation propagation biological media. most them are complicated difficult understood researchers, especially beginners. That’s why this paper was introduced. Our aims simplify understanding biomedical waves. We developed for entire process. The introduced based three steps: (1) pulsed laser stimulation, (2) light diffusion, (3) stress wave propagation. has implemented utilizing COMSOL Multiphysics, which relies finite element method (FEM) principle. in-silico time-dependent study's results confirmed that simple, efficient, accurate, quick starting point researchers simulate signals' any software such multiphysics.

Language: Английский

深层生物组织光学技术发展及其应用(特邀) DOI Open Access

赖溥祥 Lai Puxiang,

Qi Zhao,

周颖颖 Zhou Yingying

et al.

Chinese Journal of Lasers, Journal Year: 2024, Volume and Issue: 51(1), P. 0107003 - 0107003

Published: Jan. 1, 2024

光学技术在生物医学中扮演着越来越重要的角色,其非电离辐射、高分辨率、高对比度和对生物组织异变高度灵敏等特性使其非常适用于生物组织的研究,包括成像、传感、治疗、刺激以及控制等。然而由于光折射因子在生物组织中的分布是不均匀的,光在生物组织中的传播会受到很强的散射影响,故纯光学技术的穿透深度和空间分辨率是"鱼和熊掌不可兼得";高分辨率光学成像应用仅限于样品浅表层,当成像深度增加时分辨率急剧下降。实现光在深层生物组织里的高分辨率成像或应用是人们期盼已久的目标。近年来,为解决这一问题,研究者提出了不同的方法,例如切换到更长的光波长以减小组织散射系数,在信号检测时将漫射光转换为散射不明显的超声信号,逆转或者预先补偿由光的多次散射所带来的相位畸变,或借助光纤等微创光学通道实现深层生物组织的高分辨率光学成像、刺激等。基于团队在深层生物组织光学相关领域多年的耕耘,从光在生物组织中的传播特性出发,梳理和总结了近年来研究人员在光-声结合和光学波前整形技术等方面展开的诸多探索,以及在生物组织操控、成像、光学计算以及人工智能等领域中的应用尝试。虽然尚有诸多不足,但随着硬件设备的更新和计算技术的发展,在不远的将来有望实现活体深层生物组织光学高分辨率应用。在这一求索过程中,新方法和新能力将不断激发新的应用灵感,为光学尤其是生物医学光子学带来全新的理念和机遇。

Citations

9

All-optical phase conjugation using diffractive wavefront processing DOI Creative Commons
Che‐Yung Shen, Jingxi Li, Tianyi Gan

et al.

Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)

Published: June 11, 2024

Language: Английский

Citations

7

Image-guided computational holographic wavefront shaping DOI
Omri Haim, Jeremy Boger-Lombard, Ori Katz

et al.

Nature Photonics, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 18, 2024

Language: Английский

Citations

6

Overcoming the diffraction limit by exploiting unmeasured scattering media DOI Creative Commons
Shuai Sun,

Zhen-Wu Nie,

Long-Kun Du

et al.

Optica, Journal Year: 2024, Volume and Issue: 11(3), P. 385 - 385

Published: Feb. 20, 2024

Scattering is not necessarily an obstacle to imaging. It can help enhance imaging performance beyond the reach of a lens system. However, current scattering-enhanced systems require prior knowledge transmission matrix. There are also some techniques that do such see through strongly scattering media, but results still limited by optics used. Here we propose overcoming diffraction limit visually opaque diffuser. By controlling distance between diffuser and system, light with higher spatial frequencies scattered into entrance pupil. With deformed wavefront corrected, experimentally achieved 3.39× enhancement Rayleigh limit. In addition, our method works well for objects 4× larger than memory effect range maintain super-resolution depth field 6.6× achieve. Using method, obstructive medium throughput even though matrix has been measured beforehand.

Language: Английский

Citations

4

Light correcting light with nonlinear optics DOI Creative Commons
Sachleen Singh, Bereneice Sephton, Wagner Tavares Buono

et al.

Advanced Photonics, Journal Year: 2024, Volume and Issue: 6(02)

Published: Feb. 28, 2024

Structured light, where complex optical fields are tailored in all their degrees of freedom, has become highly topical late, advanced by a sophisticated toolkit comprising both linear and nonlinear optics. Removing undesired structure from light is far less developed, leveraging mostly on inverting the distortion, e.g., with adaptive optics or inverse transmission matrix channel, requiring that distortion be fully characterized through appropriate measurement. We show distortions spatially structured can corrected difference-frequency generation crystal without any need for to known. demonstrate versatility our approach using wide range aberrations modes, including higher-order orbital angular momentum (OAM) beams, showing excellent recovery original undistorted field. To highlight efficacy this process, we deploy system prepare-and-measure communications link OAM, minimal cross talk even when channel aberrated, outline how could extended alternative experimental modalities processes. Our demonstration light-correcting measurement opens an measurement-free error correction classical quantum direct applications imaging, sensing, communication.

Language: Английский

Citations

4

Light focusing and additive manufacturing through highly scattering media using upconversion nanoparticles DOI
Qianyi Zhang, Antoine Boniface, V.K. Parashar

et al.

Deleted Journal, Journal Year: 2025, Volume and Issue: 6(1), P. 1 - 1

Published: Jan. 1, 2025

Language: Английский

Citations

0

Output control of dissipative nonlinear multimode amplifiers using spacetime symmetry mapping DOI
Chun‐Wei Chen, Kabish Wisal, Mathias Fink

et al.

Nature Physics, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

Citations

0

Deep neural network surrogate models of transmission matrix for scattering imaging DOI
Xiangqing Li,

Wenxuan Xia,

Qiang Liang

et al.

Optics & Laser Technology, Journal Year: 2025, Volume and Issue: 189, P. 113135 - 113135

Published: May 13, 2025

Language: Английский

Citations

0

Photoacoustic guided wavefront shaping using digital micromirror devices DOI

Jiahui Wu,

Ting Feng, Qian Chen

et al.

Optics & Laser Technology, Journal Year: 2024, Volume and Issue: 174, P. 110570 - 110570

Published: Jan. 14, 2024

Language: Английский

Citations

3

Non-Invasive Self-Adaptive Information States Acquisition inside Dynamic Scattering Spaces DOI Creative Commons
Ruifeng Li, Jinyan Ma, Da Li

et al.

Research, Journal Year: 2024, Volume and Issue: 7

Published: Jan. 1, 2024

Pushing the information states' acquisition efficiency has been a long-held goal to reach measurement precision limit inside scattering spaces. Recent studies have indicated that maximal states can be attained through engineered modes; however, partial intrusion is generally required. While non-invasive designs substantially explored across diverse physical scenarios, of dynamic spaces remains challenging due intractable non-unique mapping problem, particularly in context multi-target scenarios. Here, we establish feasibility experimentally for first time by introducing tandem-generated adversarial network framework To illustrate framework's efficacy, demonstrate efficient scenarios achieve Fisher solely utilization external matrix system. Our work provides insightful perspectives precise measurements complex systems.

Language: Английский

Citations

3