Current Opinion in Microbiology,
Journal Year:
2024,
Volume and Issue:
80, P. 102496 - 102496
Published: June 13, 2024
Symbiotic
interactions
between
fungi
and
bacteria
range
from
positive
to
negative.
They
are
ubiquitous
in
free-living
as
well
host-associated
microbial
communities
worldwide.
Yet,
the
impact
of
fungal-bacterial
symbioses
on
organization
dynamics
is
uncertain.
There
two
reasons
for
this
uncertainty:
(1)
knowledge
gaps
understanding
genetic
mechanisms
underpinning
(2)
prevailing
interpretations
ecological
theory
that
favor
antagonistic
drivers
stabilizing
biological
despite
existence
models
emphasizing
contributions
interactions.
This
review
synthesizes
information
common
soil
polymicrobial
biofilms.
The
interdomain
partnerships
considered
context
relevant
community
ecology
models,
which
discussed
critically.
Frontiers in Microbiology,
Journal Year:
2024,
Volume and Issue:
15
Published: Feb. 23, 2024
Biofilms
account
for
a
great
deal
of
infectious
diseases
and
contribute
significantly
to
antimicrobial
resistance.
Efflux
pumps
confer
resistance
microorganisms
involve
multiple
processes
biofilm
formation.
pump
inhibitors
(EPIs)
are
attracting
considerable
attention
as
inhibition
strategy.
The
regulatory
functions
efflux
in
formation
such
mediating
adherence,
quorum
sensing
(QS)
systems,
the
expression
biofilm-associated
genes
have
been
increasingly
identified.
versatile
properties
both
positive
negative
effects
on
Furthermore,
function
species-specific.
Therefore,
this
review
aims
detail
double-edged
sword
role
provide
potential
targets
give
an
overview
EPIs
Nature Microbiology,
Journal Year:
2024,
Volume and Issue:
9(4), P. 1089 - 1102
Published: March 27, 2024
Abstract
Secretion
systems
are
protein
export
machines
that
enable
bacteria
to
exploit
their
environment
through
the
release
of
effectors.
The
Type
9
System
(T9SS)
is
responsible
for
across
outer
membrane
(OM)
phylum
Bacteroidota.
Here
we
trap
T9SS
Flavobacterium
johnsoniae
in
process
substrate
transport
by
disrupting
motor
complex.
Cryo-EM
analysis
purified
substrate-bound
translocons
reveals
an
extended
translocon
structure
which
previously
described
core
augmented
a
periplasmic
incorporating
proteins
SprE,
PorD
and
homologue
canonical
chaperone
Skp.
Substrate
bind
extracellular
loops
carrier
within
pore.
As
intermediates
accumulate
on
when
energetic
input
removed,
deduce
substrate–carrier
complex
from
energy-requiring
step
transport.
Biophysical Reviews,
Journal Year:
2024,
Volume and Issue:
16(2), P. 173 - 188
Published: April 1, 2024
Microbes
thrive
in
diverse
porous
environments-from
soil
and
riverbeds
to
human
lungs
cancer
tissues-spanning
multiple
scales
conditions.
Short-
long-term
fluctuations
local
factors
induce
spatio-temporal
heterogeneities,
often
leading
physiologically
stressful
settings.
How
microbes
respond
adapt
such
biophysical
constraints
is
an
active
field
of
research
where
considerable
insight
has
been
gained
over
the
last
decades.
With
a
focus
on
bacteria,
here
we
review
recent
advances
self-organization
dispersal
inorganic
organic
settings,
highlighting
role
interactions
feedback
that
mediates
microbial
survival
fitness.
We
discuss
open
questions
opportunities
for
using
integrative
approaches
advance
our
understanding
strategies
which
employ
at
various
make
settings
habitable.
Current Opinion in Microbiology,
Journal Year:
2024,
Volume and Issue:
80, P. 102496 - 102496
Published: June 13, 2024
Symbiotic
interactions
between
fungi
and
bacteria
range
from
positive
to
negative.
They
are
ubiquitous
in
free-living
as
well
host-associated
microbial
communities
worldwide.
Yet,
the
impact
of
fungal-bacterial
symbioses
on
organization
dynamics
is
uncertain.
There
two
reasons
for
this
uncertainty:
(1)
knowledge
gaps
understanding
genetic
mechanisms
underpinning
(2)
prevailing
interpretations
ecological
theory
that
favor
antagonistic
drivers
stabilizing
biological
despite
existence
models
emphasizing
contributions
interactions.
This
review
synthesizes
information
common
soil
polymicrobial
biofilms.
The
interdomain
partnerships
considered
context
relevant
community
ecology
models,
which
discussed
critically.
