Reply to ‘Issues of parcellation in the calculation of structure–function coupling’ DOI Creative Commons
Panagiotis Fotiadis, Danielle S. Bassett

Nature reviews. Neuroscience, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 14, 2024

Language: Английский

Zero-phase-delay connectivity increases the reliability, concordance with structure, and prognostic ability of functional connectivity metrics DOI Creative Commons
Chirag Mehra, Ahmad Beyh, Petroula Laiou

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 4, 2025

Abstract Zero-phase-delay synchrony between the activity of distant neural populations has been robustly observed. Nevertheless, contemporary electroencephalography and magnetencephalography functional connectivity analyses typically exclude zero-phase-delay connections, assuming that they are predominantly artefactual. However, effects excluding them on performance metrics as potential biomarkers unknown. Here, we showed most cortico-cortical connections occur with zero- or near-zero phase-delay, even where such was unlikely to be Including, rather than excluding, increased reliability, concordance structural connectivity, predictive validity (for longitudinal changes in cognition) metrics. We found penalised strength strongest structurally connected regions: stronger led phase-delays closer zero, mediated by a shorter signal propagation time. Our findings challenge generally accepted assumptions zero-phase-exclusive methods superior zero-phase-inclusive methods.

Language: Английский

Citations

0
Connectome harmonic decomposition tracks the presence of disconnected consciousness during ketamine-induced unresponsiveness DOI Creative Commons
Milan Van Maldegem, Jakub Vohryzek, Selen Atasoy

et al.

British Journal of Anaesthesia, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский

Citations

0
Topographic, cognitive, and neurobiological profiling of the interdependent structural and functional modules of the brain DOI Creative Commons
Xiaoyue Wang,

Lianglong Sun,

Xinyuan Liang

et al.

Science Bulletin, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский

Citations

0
The overgrowth of structure-function coupling in premature brain during infancy DOI Creative Commons

Rong Wang,

Tianyu Fang,

Yue Zhang

et al.

Developmental Cognitive Neuroscience, Journal Year: 2025, Volume and Issue: 72, P. 101535 - 101535

Published: Feb. 21, 2025

Language: Английский

Citations

0
Exploring the transmission of cognitive task information through optimal brain pathways DOI Creative Commons
Zhengdong Wang,

Yifeixue Yang,

Ziyi Huang

et al.

PLoS Computational Biology, Journal Year: 2025, Volume and Issue: 21(3), P. e1012870 - e1012870

Published: March 7, 2025

Understanding the large-scale information processing that underlies complex human cognition is central goal of cognitive neuroscience. While emerging activity flow models demonstrate task transferred by interregional functional or structural connectivity, graph-theory-based typically assume neural communication occurs via shortest path brain networks. However, whether optimal route for empirical transmission remains unclear. Based on a mapping framework, we found performance prediction with was significantly lower than direct path. The routing superior to other network strategies, including search information, ensembles, and navigation. Intriguingly, outperformed in when physical distance constraint asymmetric contribution were simultaneously considered. This study not only challenges assumption through but also suggests constrained spatial embedding network.

Language: Английский

Citations

0
Amyloid pathology related to aberrant structure-function coupling of brain networks in Alzheimer’s disease: insights from [18F]-florbetapir PET imaging DOI
Haojie Chen, Mingkai Zhang,

Min Wei

et al.

European Journal of Nuclear Medicine and Molecular Imaging, Journal Year: 2025, Volume and Issue: unknown

Published: March 7, 2025

Language: Английский

Citations

0
Lifespan trajectories of fornix volume and tractography: a 5.0 T MRI study DOI
Q. Hu,

Jia Xu,

Sirui Li

et al.

Cerebral Cortex, Journal Year: 2025, Volume and Issue: 35(3)

Published: March 1, 2025

Abstract The fornix, playing a critical role in memory formation and maintenance, is recognized as an ultra-early biomarker for dementia. However, its trajectory during healthy aging remains incompletely understood. This study employed ultra-high-field 5.0 T MRI to acquire high-resolution anatomical multishell diffusion imaging data from 376 adults aged 18 85. aim was correlate fornix characteristics with cognitive performance across multiple domains map lifespan trajectories. Using these data, we quantified volume tractography. Lifespan trajectories were identified by computing age-specific average patterns, which revealed distinct changes. Notably, nonlinear declines observed, contrasting fiber tract peaks between ages 40, subsequently influenced volume-connectivity interactions. Additionally, shift predominant left-side right-side dominance noted aging. Regression analyses indicated that variations structure significantly moderated, rather than mediated, age-related differences performance. These results provide novel insights into the of fornix’s morphology structural connectivity individual

Language: Английский

Citations

0
The Relationship Between Grip Strength and Cognitive Impairment: Evidence From NHANES 2011–2014 DOI Creative Commons

Wenyi Nie,

Jingqing Hu

Brain and Behavior, Journal Year: 2025, Volume and Issue: 15(3)

Published: March 1, 2025

ABSTRACT Background Prior research has consistently shown an association between muscle strength and various metabolic diseases. However, the relationship cognitive impairment remains elusive. Methods Using data from 2011–2014 National Health Nutrition Examination Survey (NHANES), we investigated impairment. We used multivariate logistic regression, restricted cubic spline regression (RCS), threshold effects to investigate impact of on function. In addition, analyzed correlation in subgroups age, gender, race, education, smoking status, drinking hypertension, diabetes, heart disease. Results 2124 participants were ultimately included for further analysis. Multivariate trend testing, RCS analysis showed a non‐linear negative Threshold effect suggests that when reaches certain value, this undergoes significant changes. three function scoring tests, interaction was only observed racial subgroup. Conclusion This study function, which may have effect. Further longitudinal studies are needed elucidate its potential mechanisms.

Language: Английский

Citations

0
Relationships and representations of brain structures, connectivity, dynamics and functions DOI
Oliver Schmitt

Progress in Neuro-Psychopharmacology and Biological Psychiatry, Journal Year: 2025, Volume and Issue: unknown, P. 111332 - 111332

Published: March 1, 2025

Language: Английский

Citations

0
Investigating the predictive models of efficacy of accelerated neuronavigation-guided rTMS for suicidal depression based on multimodal large-scale brain networks DOI Creative Commons

Fen Pan,

Junle Li,

Suhui Jin

et al.

International Journal of Clinical and Health Psychology, Journal Year: 2025, Volume and Issue: 25(1), P. 100564 - 100564

Published: Jan. 1, 2025

Language: Английский

Citations

0