NeuroImage, Journal Year: 2025, Volume and Issue: unknown, P. 121277 - 121277
Published: May 1, 2025
Language: Английский
Hearing Research, Journal Year: 2025, Volume and Issue: unknown, P. 109184 - 109184
Published: Jan. 1, 2025
Language: Английский
Citations
1
The Cerebellum, Journal Year: 2025, Volume and Issue: 24(1)
Published: Jan. 3, 2025
Language: Английский
Citations
0
Brain and Behavior, Journal Year: 2025, Volume and Issue: 15(2)
Published: Feb. 1, 2025
The cerebellum's role extends beyond motor control, impacting various cognitive functions. A growing body of evidence supports the idea that cerebellum optimizes performance across domains, suggesting critical connectivity with neocortex. This study investigates how cerebellar transcranial direct current stimulation (tDCS) targeting right Crus II region modulates functional brain connectivity. Using a within-subject design, 21 healthy participants underwent both sham and anodal tDCS at 2 mA during 20 min concurrent resting-state fMRI sessions. Data was preprocessed, changes were examined using seed-to-voxel analysis. Given potential impact dysfunctions on symptoms associated autism spectrum disorders, we also assessed individual quotient (AQ) scores might influence Moreover, electrical field simulations computed for each participant to explore effects differences. Results indicated increased between inferior frontal gyrus (IFG) active compared stimulation. IFG (part Action Observation Network) plays crucial in understanding actions intentions others, implicating higher-order processes. In addition, linear mixed-effects models revealed an interaction electric strength AQ scores, are based psychobiological Cerebellar significantly altered connectivity, particularly IFG, involved social cognition. These findings contribute our highlighting its processes therapeutic applications, such as disorders.
Language: Английский
Citations
0
bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 22, 2025
Abstract We exploit identification of neuron types during extracellular recording to demonstrate how the cerebellar cortex’s well-established architecture transforms inputs into outputs. During smooth pursuit eye movements, floccular complex performs distinct input-output transformations temporal dynamics and directional response properties. The responses different interneuron localize circuit mechanisms each transformation. Mossy fibers unipolar brush cells emphasize position uniformly across cardinal axes; Purkinje molecular layer interneurons code velocity along directionally biased Golgi show unmodulated firing. Differential properties transformation last-order cells. pinpoint site granule Specific cell population allow required in area we study generalize many transformations, providing a complete framework understand computation. Impact statement dissect computations performed by cerebellum an exemplar sensory-motor behavior, taking advantage knowledge architecture, existence discrete types, newfound ability identify from recordings. Our results describe contributions major computations, needed support those create basis set enable temporally-specific motor behavior learning.
Language: Английский
Citations
0
Neural Networks, Journal Year: 2025, Volume and Issue: 188, P. 107538 - 107538
Published: April 23, 2025
Linking cellular-level phenomena to brain architecture and behavior is a holy grail for theoretical computational neuroscience. Advances in neuroinformatics have recently allowed scientists embed spiking neural networks of the cerebellum with realistic neuron models multiple synaptic plasticity rules into sensorimotor controllers. By minimizing distance (error) between desired actual sensory state, exploiting prediction, cerebellar network acquires knowledge about body-environment interaction generates corrective signals. In doing so, implements generalized algorithm, allowing it "to learn predict timing correlated events" rich set behavioral contexts. Plastic changes evolve trial by are distributed over synapses, regulating neuronal discharge fine-tuning high-speed movements on millisecond timescale. Thus, built-in controllers, among various approaches studying function, helping reveal substrates learning signal coding, opening new frontiers predictive computing autonomous robots.
Language: Английский
Citations
0
bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown
Published: April 19, 2025
Abstract The cerebellum’s capacity for neural computation is arguably unmatched. Yet despite evidence of cerebellar contributions to cognition, including language, its precise role remains debated. Here, we systematically evaluate language-responsive regions using precision fMRI. We identify four that respond language across modalities (Experiments 1a-b, n=754). One region—spanning Crus I/II/lobule VIIb—is selective relative diverse non-linguistic tasks 2a-f, n=732), and the rest exhibit mixed-selective profiles. Like neocortical system, language-selective region engaged by sentence-level meanings during comprehension production 3a-c, n=105), but it less sensitive than neocortex individual word grammatical structure. Finally, all regions, especially I/II/VIIb, are functionally connected system (Experiment 4, n=85). propose these constitute components extended network, with one supporting semantic processing, other three plausibly integrating information from regions.
Language: Английский
Citations
0
The Cerebellum, Journal Year: 2025, Volume and Issue: 24(4)
Published: May 2, 2025
Language: Английский
Citations
0
NeuroImage, Journal Year: 2025, Volume and Issue: unknown, P. 121277 - 121277
Published: May 1, 2025
Language: Английский
Citations
0