Gastrointestinal cancers among Asian American and Pacific Islander populations
The Lancet Regional Health - Americas,
Journal Year:
2025,
Volume and Issue:
42, P. 100989 - 100989
Published: Jan. 10, 2025
Language: Английский
Treatment Noncompletion and Shorter Radiation Regimens Among US Patients With Prostate Cancer: A Focus on Asian American and Pacific Islander Patients
Rohit V. Mantena,
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Rishabh Bhadouriya,
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Urvish Jain
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et al.
The Prostate,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 31, 2025
ABSTRACT
Background
Higher
rates
of
radiation
therapy
(RT)
noncompletion
may
be
associated
with
certain
demographic
groups
in
patients
prostate
cancer
(PC).
We
examined
disparities
and
receipt
shorter
RT
regimens
among
disaggregated
Asian
American
Pacific
Islander
the
US.
Methods
performed
a
retrospective
cohort
analysis
all
diagnosed
localized
PC
(2004–2017)
National
Cancer
Database
who
identified
as
White,
East
Asian,
Southeast
Islander,
or
South
were
treated
definitive
RT.
The
two
primary
outcomes
1)
treatment
2)
receiving
regimens.
Regression
models
adjusted
for
relevant
sociodemographic
clinical
factors.
Results
analytic
was
comprised
143,379
[White,
n
=
140,656
(98.10%);
1,150
(0.80%);
925
(0.65%);
195
(0.14%);
453
(0.32%)].
On
multivariable
analysis,
increased
rate
compared
to
White
(Southeast
vs.
White;
OR:
1.55
[95%
CI:
1.29–1.86],
p
<
0.001).
Geographic
region
facility
within
United
States
also
significant,
from
Atlantic
(OR:
1.32
1.24–1.41],
0.001),
North
Central
1.09
1.03–1.17],
0.007),
1.54
1.41–1.68],
West
1.14
1.04–1.24],
0.005)
regions
had
higher
comparison
New
England.
Distance
facility,
presence
comorbidities,
education
attainment
significantly
impacted
well.
Additionally,
our
study
reports
short
course
substantially
SBRT
2.60
1.10–6.16],
0.030)
patients,
while
Hispanic
lower
0.48
0.40–0.57],
Furthermore,
urban
0.68
0.61–0.76],
0.001)
metro
0.50
0.39–0.65],
facilities
reduced
access
than
rural
areas.
Patients
received
Middle
3.28
2.91–3.68],
2.72
2.40–3.09],
1.53
1.34–1.75],
3.07
2.61–3.63],
2.35
2.02–2.75],
Mountain
2.45
2.01–2.97],
Conclusions
This
found
that
patients.
access–a
traditional
therapies–were
based
on
race/ethnicity
geographical
Our
findings
emphasize
heterogeneous
differences
amongst
diverse
support
need
further
research
inform
targeted
interventions.
Language: Английский
Individuals from culturally and linguistically diverse backgrounds have more advanced prostate cancer at diagnosis in Victoria, Australia
Cancer Epidemiology,
Journal Year:
2025,
Volume and Issue:
97, P. 102827 - 102827
Published: April 23, 2025
The
Australian
Cancer
Plan
prioritises
individuals
from
culturally
and
linguistically
diverse
(CALD)
backgrounds
as
a
focus
of
interventions
aimed
at
improving
cancer
care
experiences
outcomes.
We
to
investigate
differences
in
the
National
Comprehensive
Network
(NCCN)
risk
category
classification
prostate
(PCa)
diagnosis
between
CALD
non-CALD
populations.
included
Victorian
Prostate
Outcomes
Registry
registrants
with
PCa
(February
2009-August
2022)
country-of-birth
data.
status
was
defined
birth
mainly
non-English-speaking
country
versus
Australia
or
English-speaking
(MESC).
were
further
sub-grouped
by
preferred
spoken
language:
non-English-speaking.
estimated
effect
on
NCCN
categories
using
partial
proportional
ordinal
logistic
regression.
There
25,951
individuals:
18,392
(71
%)
Australian-born,
5046
(19
2513
(10
MESC-born.
Of
4872
preferred-language
data,
498
speaking
language
other
than
English.
Compared
Australian-born
individuals,
presented
less
low-risk
(15
%
vs
22
but
more
high-risk
(32
21
metastatic
(18
8
disease.
had
significantly
advanced
(regional
metastatic)
disease
(adjusted
odds
ratio
[aOR]=1.17,
95
confidence
interval
[CI]=1.06-1.29).
Non-English-speaking
(aOR=1.54,
CI=1.23-1.94).
Individuals
greater
presenting
PCa.
Improving
early
detection
for
requires
investigation
underlying
factors
plan
effective
interventions.
Language: Английский