Interstitial fluid-based wearable biosensors for minimally invasive healthcare and biomedical applications DOI Creative Commons
Zixiong Wu, Zheng Qiao, Shuwen Chen

et al.

Communications Materials, Journal Year: 2024, Volume and Issue: 5(1)

Published: March 13, 2024

Abstract Interstitial fluid (ISF), a biological rich in diverse biomarkers and analytes similar to blood composition, has garnered significant attention as valuable source of clinically relevant information. Consequently, ISF-based wearable biosensors are emerging powerful tools for non-invasive minimally invasive disease diagnosis, personalized medicine, other healthcare biomedical applications. This review provides comprehensive overview recent advancements biosensors, with particular focus on ISF sensors. We first offer insights into sampling techniques discuss sensing strategies that encompass materials, fabrication methods, mechanisms. Then, we present their Finally, address the challenges faced this field forward-looking perspective promising future directions.

Language: Английский

Technology Roadmap for Flexible Sensors DOI Creative Commons
Yifei Luo, Mohammad Reza Abidian, Jong‐Hyun Ahn

et al.

ACS Nano, Journal Year: 2023, Volume and Issue: 17(6), P. 5211 - 5295

Published: March 9, 2023

Humans rely increasingly on sensors to address grand challenges and improve quality of life in the era digitalization big data. For ubiquitous sensing, flexible are developed overcome limitations conventional rigid counterparts. Despite rapid advancement bench-side research over last decade, market adoption remains limited. To ease expedite their deployment, here, we identify bottlenecks hindering maturation propose promising solutions. We first analyze achieving satisfactory sensing performance for real-world applications then summarize issues compatible sensor-biology interfaces, followed by brief discussions powering connecting sensor networks. Issues en route commercialization sustainable growth sector also analyzed, highlighting environmental concerns emphasizing nontechnical such as business, regulatory, ethical considerations. Additionally, look at future intelligent sensors. In proposing a comprehensive roadmap, hope steer efforts towards common goals guide coordinated development strategies from disparate communities. Through collaborative efforts, scientific breakthroughs can be made sooner capitalized betterment humanity.

Language: Английский

Citations

697

Device integration of electrochemical biosensors DOI Open Access
Jie Wu, Hong Liu, Weiwei Chen

et al.

Nature Reviews Bioengineering, Journal Year: 2023, Volume and Issue: 1(5), P. 346 - 360

Published: Feb. 24, 2023

Language: Английский

Citations

364

Defect engineering of two-dimensional materials for advanced energy conversion and storage DOI
Fu Liu, Zhanxi Fan

Chemical Society Reviews, Journal Year: 2023, Volume and Issue: 52(5), P. 1723 - 1772

Published: Jan. 1, 2023

Defective two-dimensional (2D) materials show huge potential for energy-related fields. This review overviews the formation/evolution mechanisms and engineering strategies of defects in 2D materials, which enable enhanced electrode reaction kinetics.

Language: Английский

Citations

201

Stretchable graphene–hydrogel interfaces for wearable and implantable bioelectronics DOI
Yuyao Lu, Geng Yang, Shenqiang Wang

et al.

Nature Electronics, Journal Year: 2023, Volume and Issue: 7(1), P. 51 - 65

Published: Dec. 14, 2023

Language: Английский

Citations

192

Green Flexible Electronics: Natural Materials, Fabrication, and Applications DOI

Zengyu Hui,

Linrong Zhang,

Guozhang Ren

et al.

Advanced Materials, Journal Year: 2023, Volume and Issue: 35(28)

Published: Feb. 10, 2023

Abstract The emergence of plastic electronics satisfies the increasing demand for flexible electronics. However, it has caused severe ecological problems. Flexible based on natural materials are to hopefully realize “green” and eco‐friendly concept. Herein, recent advances in design fabrication green reviewed. First, this review comprehensively introduces various derivatives, focusing particularly fibroin silk, wood paper, plants, biomass. Second, techniques modifying materials, including physical chemical methods, presented, after which their merits demerits thoroughly discussed. Green comprising electrical wires/electrodes, antennas, thermal management devices, transistors, memristors, sensors, energy‐harvesting energy‐storage displays, actuators, electromagnetic shielding, integration systems, described detail. Finally, perspectives existing challenges opportunities employ presented.

Language: Английский

Citations

146

Rational Design of Flexible Zn-Based Batteries for Wearable Electronic Devices DOI
Xiao Xiao, Zhiyang Zheng, Xiongwei Zhong

et al.

ACS Nano, Journal Year: 2023, Volume and Issue: 17(3), P. 1764 - 1802

Published: Jan. 30, 2023

The advent of 5G and the Internet Things has spawned a demand for wearable electronic devices. However, lack suitable flexible energy storage system become "Achilles' Heel" Additional problems during transformation battery structure from conventional to also present severe challenge design. Flexible Zn-based batteries, including Zn-ion batteries Zn–air have long been considered promising candidates due their high safety, eco-efficiency, substantial reserve, low cost. In past decade, researchers come up with elaborate designs each portion improve ionic conductivities, mechanical properties, environment adaptabilities, scalable productions. It would be helpful summarize reported strategies compare pros cons facilitate further research toward commercialization batteries. this review, current progress in developing is comprehensively reviewed, electrolytes, cathodes, anodes, discussed terms synthesis, characterization, performance validation. By clarifying challenges design, we methodology previous investigations propose future development. end, paradigm summarized fit burgeoning requirement devices an iterative process, which will benefit development

Language: Английский

Citations

138

Engineering of Chain Rigidity and Hydrogen Bond Cross‐Linking toward Ultra‐Strong, Healable, Recyclable, and Water‐Resistant Elastomers DOI
Zhiwei Guo, Xingyuan Lu, Xiaohan Wang

et al.

Advanced Materials, Journal Year: 2023, Volume and Issue: 35(21)

Published: Feb. 28, 2023

High-performance elastomers have gained significant interest because of their wide applications in industry and our daily life. However, it remains a great challenge to fabricate simultaneously integrating ultra-high mechanical strength, toughness, excellent healing recycling capacities. In this study, ultra-strong, healable, recyclable are fabricated by dynamically cross-linking copolymers composed rigid polyimide (PI) segments soft poly(urea-urethane) (PUU) with hydrogen bonds. The elastomers, which denoted as PIPUU, record-high tensile strength ≈142 MPa an extremely high toughness ≈527 MJ m-3 . structure the PIPUU elastomer contains hydrogen-bond-cross-linked elastic matrix homogenously dispersed nanostructures. PI self-assemble generate phase-separated nanostructures that serve nanofillers significantly strengthen elastomers. Meanwhile, is PUU cross-linked reversible bonds, largely enhance elastomer. can be healed recycled restore original strength. Moreover, performance hydrophobic segments, scratch-, puncture-, water-resistant.

Language: Английский

Citations

130

Artificial intelligence-powered electronic skin DOI
Changhao Xu,

Samuel A. Solomon,

Wei Gao

et al.

Nature Machine Intelligence, Journal Year: 2023, Volume and Issue: 5(12), P. 1344 - 1355

Published: Dec. 18, 2023

Language: Английский

Citations

96

Artificial intelligence enhanced sensors - enabling technologies to next-generation healthcare and biomedical platform DOI Creative Commons
Chan Wang, Tianyiyi He, Hong Zhou

et al.

Bioelectronic Medicine, Journal Year: 2023, Volume and Issue: 9(1)

Published: Aug. 2, 2023

The fourth industrial revolution has led to the development and application of health monitoring sensors that are characterized by digitalization intelligence. These have extensive applications in medical care, personal management, elderly sports, other fields, providing people with more convenient real-time services. However, these face limitations such as noise drift, difficulty extracting useful information from large amounts data, lack feedback or control signals. artificial intelligence provided powerful tools algorithms for data processing analysis, enabling intelligent monitoring, achieving high-precision predictions decisions. By integrating Internet Things, intelligence, sensors, it becomes possible realize a closed-loop system functions collection, online diagnosis, treatment recommendations. This review focuses on healthcare enhanced technologies aspects materials, device structure, integration, scenarios. Specifically, this first introduces great advances wearable respiration rate, heart pulse, sweat, tears; implantable cardiovascular nerve signal acquisition, neurotransmitter monitoring; soft electronics precise therapy. Then, recent volatile organic compound detection highlighted. Next, current developments human-machine interfaces, AI-enhanced multimode self-sustainable systems reviewed. Last, perspective future directions further research is also provided. In summary, fusion will provide intelligent, convenient, secure services next-generation biomedical applications.

Language: Английский

Citations

95

Flexible Organic Transistors for Biosensing: Devices and Applications DOI Creative Commons
Jiajun Song, Hong Liu, Zeyu Zhao

et al.

Advanced Materials, Journal Year: 2023, Volume and Issue: unknown

Published: Feb. 28, 2023

Abstract Flexible and stretchable biosensors can offer seamless conformable biological–electronic interfaces for continuously acquiring high‐fidelity signals, permitting numerous emerging applications. Organic thin film transistors (OTFTs) are ideal transducers flexible biosensing due to their soft nature, inherent amplification function, biocompatibility, ease of functionalization, low cost, device diversity. In consideration the rapid advances in flexible‐OTFT‐based broad applications, herein, a timely comprehensive review is provided. It starts with detailed introduction features various OTFTs including organic field‐effect electrochemical transistors, functionalization strategies biosensing, highlight on seminal work up‐to‐date achievements. Then, applications wearable, implantable, portable electronics, as well neuromorphic biointerfaces detailed. Subsequently, special attention paid planar fibrous devices. The routes impart stretchability, structural engineering material engineering, discussed, implementations e‐skin smart textiles included. Finally, remaining challenges future opportunities this field summarized.

Language: Английский

Citations

92