Arginase inhibitor reduces fungal dissemination in murine pulmonary cryptococcosis by promoting anti-cryptococcal immunity DOI
Adithap Hansakon, Pornpimon Angkasekwinai

International Immunopharmacology, Journal Year: 2024, Volume and Issue: 132, P. 111995 - 111995

Published: April 5, 2024

Language: Английский

A human commensal-pathogenic fungus suppresses host immunity via targeting TBK1 DOI
Gang Luo,

Jingkai Zhang,

Tianxu Wang

et al.

Cell Host & Microbe, Journal Year: 2024, Volume and Issue: 32(9), P. 1536 - 1551.e6

Published: July 30, 2024

Language: Английский

Citations

3
Aspergillus fumigatus conidial surface-associated proteome reveals factors for fungal evasion and host immunity modulation DOI
Camila Figueiredo Pinzan, Clara Valero, Patrícia Alves de Castro

et al.

Nature Microbiology, Journal Year: 2024, Volume and Issue: 9(10), P. 2710 - 2726

Published: Aug. 27, 2024

Language: Английский

Citations

3
How metals fuel fungal virulence, yet promote anti-fungal immunity DOI Creative Commons

Alanoud Alselami,

Rebecca A. Drummond

Disease Models & Mechanisms, Journal Year: 2023, Volume and Issue: 16(10)

Published: Oct. 1, 2023

Invasive fungal infections represent a significant global health problem, and present several clinical challenges, including limited treatment options, increasing rates of antifungal drug resistance compounding comorbidities in affected patients. Metals, such as copper, iron zinc, are critical for various biological cellular processes across phyla. In mammals, these metals important determinants immune responses, but pathogenic microbes, fungi, also require access to fuel their own growth drive expression major virulence traits. Therefore, host cells have developed strategies either restrict induce starvation invading pathogens or deploy toxic concentrations within phagosomes cause metal poisoning. this Review, we describe the mechanisms regulating scavenging detoxification zinc importance infection. We outline how involved responses consequences deficiencies overloads on controls invasive infections.

Language: Английский

Citations

7
Genetics and Infection Biology of the Entomopathogenic Fungi DOI
Hong Song, Junmei Shang, Yanlei Sun

et al.

Springer eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 309 - 331

Published: Jan. 1, 2024

Language: Английский

Citations

2
Arginase inhibitor reduces fungal dissemination in murine pulmonary cryptococcosis by promoting anti-cryptococcal immunity DOI
Adithap Hansakon, Pornpimon Angkasekwinai

International Immunopharmacology, Journal Year: 2024, Volume and Issue: 132, P. 111995 - 111995

Published: April 5, 2024

Language: Английский

Citations

2