Journal of Nanobiotechnology,
Journal Year:
2025,
Volume and Issue:
23(1)
Published: March 7, 2025
Cryopreservation
techniques
have
been
widely
used,
especially
in
biomedical
applications
and
preservation
of
germplasm
resources.
Ideally,
biological
materials
would
maintain
functional
integrity
as
well
a
normal
structure
can
be
recovered
when
needed.
However,
this
tool
does
not
work
all
the
time.
Ice
formation
growth
are
key
challenges.
The
other
major
reason
is
that
cryoprotective
agents
(CPAs)
currently
used
do
meet
these
needs
always
accompanied
by
their
cytotoxicity.
A
comprehensive
synergistic
approach
focuses
on
overall
frozen
system
crucial
for
evolution
cryopreservation
methods.
In
review,
we
first
summarize
fundamental
damage
mechanisms
during
cryopreservation,
common
cryoprotectants
limitations.
Next,
discuss
interact
with
ice
to
improve
outcomes.
We
evaluated
natural
synthetic
materials,
including
sugars
polymers,
AFPs
mimics,
nucleators,
hydrogels.
addition,
biochemical
regulation,
which
enhances
tolerance
biosamples
cryopreservation-induced
stresses,
was
also
mentioned.
Nanotechnology,
cell
encapsulation,
cryomesh,
isochoric
freezing,
such
scalable
approaches,
further
discussed
cryopreservation.
Finally,
future
research
directions
field
efficient
proposed.
emphasized
need
multidisciplinary
progress
address
combination
cryobiology
technologies,
biology,
nanotechnology,
microfluidics,
3D
bioprinting,
highlighted.
Advanced Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 26, 2025
Abstract
Weaving,
a
pivotal
technique
in
human
construction
activities
since
the
Neolithic
era,
remains
unattainable
modern
concrete
construction.
Here,
novel
particle‐polymer
coalescence
strategy
is
proposed,
which
involves
electrostatic,
bridging,
coordinating,
and
hydrogen
bonding
interactions,
to
establish
balanced
particle
cohesion,
enabling
fabrication
of
stretchable
cement
slurry.
The
bending,
knotting,
coiling,
winding,
interlacing
filaments
for
structural
textiles
successfully
realized
beyond
traditional
formwork
casting,
grouting,
3D‐printing,
fabricate
first‐ever
Chinese
knot
woven
with
cement.
Weaving
builds
triaxially
cross‐penetrating
structure
that
greatly
promotes
interlayer
strength
toughness
by
≈208.5%
676.5%
compared
state‐of‐the‐art
layer‐by‐layer
3D
printed
structure.
These
findings
not
only
make
breakthrough
technology
but
also
provide
solutions
fabricating
multi‐directional
structures
great
engineering‐application
potentials.
Chemical Reviews,
Journal Year:
2024,
Volume and Issue:
124(18), P. 10435 - 10508
Published: Sept. 16, 2024
The
mechanical
properties
of
polymer
gels
devote
to
emerging
devices
and
machines
in
fields
such
as
biomedical
engineering,
flexible
bioelectronics,
biomimetic
actuators,
energy
harvesters.
Coupling
network
architectures
interactions
has
been
explored
regulate
supportive
characteristics
gels;
however,
systematic
reviews
correlating
mechanics
interaction
forces
at
the
molecular
structural
levels
remain
absent
field.
This
review
highlights
engineering
gel
a
comprehensive
mechanistic
understanding
regulation.
Molecular
alters
architecture
manipulates
functional
groups/moieties
level,
introducing
various
permanent
or
reversible
dynamic
bonds
dissipative
energy.
usually
uses
monomers,
cross-linkers,
chains,
other
additives.
Structural
utilizes
casting
methods,
solvent
phase
regulation,
mechanochemistry,
macromolecule
chemical
reactions,
biomanufacturing
technology
construct
tailor
topological
structures,
heterogeneous
modulus
compositions.
We
envision
that
perfect
combination
may
provide
fresh
view
extend
exciting
new
perspectives
this
burgeoning
also
summarizes
recent
representative
applications
with
excellent
properties.
Conclusions
are
provided
from
five
aspects
concise
summary,
mechanism,
biofabrication
upgraded
applications,
synergistic
methodology.
Small,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 11, 2024
Abstract
Reversible
and
recyclable
thermosets
have
garnered
increasing
attention
for
their
smart
functionality
sustainability.
However,
they
still
face
challenges
in
balancing
comprehensive
performance
dynamic
features.
Herein,
silicon
(Si)─oxygen
(O)
imidazole
units
covalent
bonds
are
coupled
to
generate
a
new
class
of
bio‐polyimines
(Bio‐Si‐PABZs),
endow
them
with
high
excellent
reprocessing
capability
acid‐degradability.
By
tailoring
the
molar
content
diamines,
this
Bio‐Si‐PABZs
displayed
both
markedly
glass
transition
temperature
(162
°C)
char
yield
at
800
°C
an
oxygen
atmosphere
(73.1%).
These
favorable
properties
outperformed
various
previously
reported
polyimines
competed
effectively
commercial
fossil‐based
polycarbonate.
Moreover,
scratch
(≈10
µ
m)
on
surface
samples
can
be
self‐healing
within
only
2
min,
effective
“
Bird
Nest
”‐to‐“
Torch
”
recycling
also
achieved
through
free
amines
solution.
Most
importantly,
bio‐based
siloxane
adhesive
derived
from
intermediate
Bio‐Si‐PABZ‐1
by
acidic
degradation
demonstrated
broad
robust
adhesion
substrates,
values
reaching
up
≈3.5
MPa.
For
first
time,
study
lays
scientific
groundwork
designing
polyimine
Si─O
units,
as
well
converting
plastic
wastes
into
thermal‐reversibility
renewable
adhesives.
Advanced Functional Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 21, 2025
Abstract
Abdominal
wall
defects,
often
caused
by
trauma,
infection,
or
tumor
resection,
pose
significant
clinical
challenges,
typically
leading
to
organ
protrusion
and
chronic
pain.
Current
repair
materials
like
polypropylene
(PP)
expanded
polytetrafluoroethylene
(ePTFE)
meshes
offer
mechanical
stability
but
can
trigger
foreign
body
reaction,
visceral
adhesions
inflammation.
While
calcium
alginate
ionic
hydrogels
(CAIHs)
present
a
biocompatible
alternative,
lack
the
strength
needed
for
abdominal
defects
repair.
This
work
develops
two
perpendicular
directions
mechanically
trained
CAIH
(PDMT‐CAIH)
cyclic
stretching,
enhancing
its
properties
without
introducing
any
additional
chemical
elements.
In
vitro
in
vivo
assessments
show
that
PDMT‐CAIH
supports
cell
proliferation,
promotes
tissue
regeneration,
significantly
reduces
adhesion
formation
compared
PP
meshes.
Additionally,
demonstrates
superior
resistance
degradation,
maintaining
structural
integrity
over
time.
These
findings
highlight
as
promising,
safer
alternative
repair,
reducing
complications
improving
outcomes
need
additives.
ACS Applied Materials & Interfaces,
Journal Year:
2025,
Volume and Issue:
17(6), P. 9981 - 9991
Published: Jan. 31, 2025
Various
glassy
hydrogels
are
developed
by
forming
dense
physical
associations
within
the
matrices,
which
exhibit
forced
elastic
deformation
and
possess
high
stiffness,
strength,
toughness.
Here,
viscoplastic
behaviors
of
hydrogel
poly(methacrylamide-co-methacrylic
acid)
investigated
stress
relaxation
creep
measurements.
We
found
that
characteristic
time
gel
is
much
smaller
than
amorphous
polymers.
The
varying
hydrogen
bond
strength
leads
to
a
broad
distribution
structural
activation
energies,
in
turn
affects
range
time.
In
presence
water,
weak
easily
disrupted
under
applied
strain,
enhancing
segmental
mobility
reducing
preyield
regime,
while
postyield
increases
slightly
since
chain
stretching
energy
barrier.
tests,
strain
rate
accelerates
at
initial
stage
due
stress-activated
segments
then
decelerates
as
chains
extensively
stretched.
required
for
during
lower
Young's
modulus
gel,
reflecting
poor
stability.
To
further
analyze
underlying
mechanism
micromechanical
model
established
based
on
an
extension
shear
transformation
zone
theory.
By
incorporating
state
variable
density,
this
can
capture
intricate
mechanical
responses
gels.
Our
findings
reveal
far
from
thermodynamic
equilibrium
state,
exhibiting
rapid
segment
external
loading.
This
work
provides
insights
dynamics
stability
materials
promote
design
applications
tough
hydrogels.
