Loom response in mouse superior colliculus depends on sensorimotor context DOI Creative Commons
Stefano Zucca, Auguste Schulz, Pedro J. Gonçalves

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 12, 2024

Visual motion is produced both by an organism's movement through the world, and objects moving in world such as potential predators. Choosing appropriate behaviour therefore requires organisms to distinguish these sources of visual motion. Here we asked how mice integrate self-movement with looming combining virtual reality neural recordings from superior colliculus (SC), a brain area important visually-guided approach avoidance behaviours. We first measured locomotion activity while animals approached object reality, same loomed at them. In cases, vision dominated superficial layers (SCs), had more influence on intermediate (SCim). addition, instinctively slowed their when nearing object, or neared To directly test animals' ability self- replayed images generated during approach. Locomotion often changed replay, showing are able establish if matched self-movement. Further, decoders trained behaviour, population SC, particularly SCim, were reliably discriminate epochs replay conclude that mouse SC encode whether arises movement, implications for understanding sensorimotor coordination dynamic environments.

Language: Английский

Genetically defined neuron types underlying visuomotor transformation in the superior colliculus DOI
Jianhua Cang, Chen Chen,

Chuiwen Li

et al.

Nature reviews. Neuroscience, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 27, 2024

Language: Английский

Citations

6
Emergent Aspects of the Integration of Sensory and Motor Functions DOI Creative Commons
Tiziana M. Florio

Brain Sciences, Journal Year: 2025, Volume and Issue: 15(2), P. 162 - 162

Published: Feb. 7, 2025

This article delves into the intricate mechanisms underlying sensory integration in executive control of movement, encompassing ideomotor activity, predictive capabilities, and motor systems. It examines interplay between functions, highlighting role cortical subcortical regions central nervous system enhancing environmental interaction. The acquisition skills, procedural memory, representation actions brain are discussed emphasizing significance mental imagery training function. development this aspect sensorimotor can help to advance our understanding interactions control, mechanisms, consciousness. Bridging theoretical insights with practical applications, it sets stage for future innovations clinical rehabilitation, assistive technology, education. ongoing exploration these domains promises uncover new pathways human capability well-being.

Language: Английский

Citations

0
Antifragile control systems in neuronal processing: a sensorimotor perspective DOI Creative Commons
Cristian Axenie

Biological Cybernetics, Journal Year: 2025, Volume and Issue: 119(2-3)

Published: Feb. 15, 2025

Language: Английский

Citations

0
Defense or death? A review of the neural mechanisms underlying sensory modality-triggered innate defensive behaviors DOI

Huating Gu,

Fan Zhao, Zhihui Liu

et al.

Current Opinion in Neurobiology, Journal Year: 2025, Volume and Issue: 92, P. 102977 - 102977

Published: Feb. 27, 2025

Language: Английский

Citations

0
Beyond Mechanism—Extending Our Concepts of Causation in Neuroscience DOI Creative Commons
Henry D. Potter, Kevin J. Mitchell

European Journal of Neuroscience, Journal Year: 2025, Volume and Issue: 61(5)

Published: March 1, 2025

ABSTRACT In neuroscience, the search for causes of behaviour is often just taken to be neural mechanisms. This view typically involves three forms causal reduction: first, from ontological level cognitive processes that mechanisms; second, activity whole brain isolated parts; and third, a consideration temporally extended, historical focus on synchronic states. While modern neuroscience has made impressive progress in identifying mechanisms, providing unprecedented real‐time control behaviour, we contend this does not amount full explanation. particular, there an attendant danger eliminating our explanatory framework, even organism itself. To fully understand need what happens when different neurons are activated, but why those things happen . paper, introduce range well‐developed, non‐reductive, extended notions causality philosophy, which neuroscientists may able draw order build more complete explanations behaviour. These include concepts criterial causation, triggering versus structuring causes, constraints, macroscopic historicity, semantic causation—all which, argue, can used undergird naturalistic understanding mental causation agent causation. can, collectively, help bring cognition itself back into picture, as unto itself, while still grounding respectable scientific terms.

Language: Английский

Citations

0
Neural dynamics in superior colliculus of freely moving mice DOI Creative Commons
Shelby L. Sharp, Jhoseph Shin, Dylan M. Martins

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown

Published: April 19, 2025

Abstract Vision is an active process that depends on head and eye movements to explore the visual environment. Superior colliculus (SC) known for its role in generating these movements, as well processing information, but has not been studied extensively during free movement complex environments. To determine impact of vision, we recorded neural activity across depth SC while simultaneously recording position. We find superficial (sSC) neurons respond input following gaze-shifting saccadic whereas deep (dSC) themselves, demonstrated by their sustained response darkness. Additionally, motor responses dSC are more correlated rather than movements. Furthermore, compared sSC gaze shift primary cortex (V1), finding similarities key types, although temporal sequences shifts differ between regions. Our results demonstrate distinct differences V1 highlighting various roles plays vision. Highlights depths superior freely moving mice measuring Neurons mouse strongly shifts, layers. primarily a movement. generally represent movement, independent input. While share with there unique profiles suggest

Language: Английский

Citations

0
Body orientation change of neighbors leads to scale-free correlation in collective motion DOI Creative Commons
Zhicheng Zheng, Tao Yuan, Yalun Xiang

et al.

Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)

Published: Oct. 17, 2024

Collective motion, such as milling, flocking, and collective turning, is a common captivating phenomenon in nature, which arises group of many self-propelled individuals using local interaction mechanisms. Recently, vision-based mechanisms, establish the relationship between visual inputs motion decisions, have been applied to model better understand emergence motion. However, previous studies often characterize input transient Boolean-like sensory stream, makes it challenging capture salient movements neighbors. This further hinders onset response mechanisms increases demands on sensing devices robotic swarms. An explicit context-related cue serving for decision-making still lacking. Here, we hypothesize that body orientation change (BOC) significant characterizing salience neighbors, facilitating response. To test our hypothesis, reveal role BOC during U-turn behaviors fish schools by reconstructing scenes from view individual fish. We find an with larger takes leading U-turns. explore this empirical finding, build pairwise mechanism basis BOC. Then, conduct experiments spin turn real-time physics simulator investigate dynamics information transfer BOC-based validate its effectiveness 50 real miniature swarm robots. The experimental results show not only facilitates directional within but also leads scale-free correlation swarm. Our study highlights practicability governed neighbor's robotics effect enhancing

Language: Английский

Citations

1
Building egocentric models of local space from retinal input DOI Creative Commons
Dylan M. Martins,

Joy M Manda,

Michael J. Goard

et al.

Current Biology, Journal Year: 2024, Volume and Issue: 34(23), P. R1185 - R1202

Published: Dec. 1, 2024

Language: Английский

Citations

1
Functional segregation and dynamic integration of the corticotectal descending signal in rat DOI Creative Commons

Hikaru Sugino,

Sho Tanno,

Tatsumi Yoshida

et al.

Neuroscience Research, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 1, 2024

Language: Английский

Citations

0
Neural substrates for saccadic modulation of visual representations in mouse superior colliculus DOI Creative Commons
Joshua B. Hunt, Anna Buteau,

Spencer Hanson

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 24, 2024

SUMMARY How do sensory systems account for stimuli generated by natural behavior? We addressed this question examining how an ethologically relevant class of saccades modulates visual representations in the mouse superior colliculus (SC), a key region sensorimotor integration. quantified saccadic modulation recording SC responses to probes presented at stochastic saccade-probe latencies. Saccades significantly impacted population probes, with early enhancement that began prior and pronounced suppression several hundred milliseconds following saccades, independent units’ response properties or directional tuning. To determine cause modulation, we fictive simulated experience during without motor output. Some units exhibited similar real suggesting sensory-driven origin while others had dissimilar indicating contribution. These findings advance our understanding neural basis coding.

Language: Английский

Citations

0