Science,
Journal Year:
2024,
Volume and Issue:
384(6699), P. 1023 - 1030
Published: May 30, 2024
Seamless
interfaces
between
electronic
devices
and
biological
tissues
stand
to
revolutionize
disease
diagnosis
treatment.
However,
biomechanical
disparities
synthetic
materials
living
present
challenges
at
bioelectrical
signal
transduction
interfaces.
We
introduce
the
active
biointegrated
electronics
(ABLE)
platform,
encompassing
capabilities
across
biogenic,
biomechanical,
properties
simultaneously.
The
biointerface,
comprising
a
bioelectronics
layout
ACS Nano,
Journal Year:
2023,
Volume and Issue:
17(6), P. 5211 - 5295
Published: March 9, 2023
Humans
rely
increasingly
on
sensors
to
address
grand
challenges
and
improve
quality
of
life
in
the
era
digitalization
big
data.
For
ubiquitous
sensing,
flexible
are
developed
overcome
limitations
conventional
rigid
counterparts.
Despite
rapid
advancement
bench-side
research
over
last
decade,
market
adoption
remains
limited.
To
ease
expedite
their
deployment,
here,
we
identify
bottlenecks
hindering
maturation
propose
promising
solutions.
We
first
analyze
achieving
satisfactory
sensing
performance
for
real-world
applications
then
summarize
issues
compatible
sensor-biology
interfaces,
followed
by
brief
discussions
powering
connecting
sensor
networks.
Issues
en
route
commercialization
sustainable
growth
sector
also
analyzed,
highlighting
environmental
concerns
emphasizing
nontechnical
such
as
business,
regulatory,
ethical
considerations.
Additionally,
look
at
future
intelligent
sensors.
In
proposing
a
comprehensive
roadmap,
hope
steer
efforts
towards
common
goals
guide
coordinated
development
strategies
from
disparate
communities.
Through
collaborative
efforts,
scientific
breakthroughs
can
be
made
sooner
capitalized
betterment
humanity.
Science Advances,
Journal Year:
2023,
Volume and Issue:
9(20)
Published: May 17, 2023
Skin
injuries
across
the
body
continue
to
disrupt
everyday
life
for
millions
of
patients
and
result
in
prolonged
hospital
stays,
infection,
death.
Advances
wound
healing
devices
have
improved
clinical
practice
but
mainly
focused
on
treating
macroscale
versus
underlying
microscale
pathophysiology.
Consensus
is
lacking
optimal
treatment
strategies
using
a
spectrum
products,
which
has
motivated
design
new
therapies.
We
summarize
advances
development
novel
drug,
biologic
biomaterial
therapies
marketed
those
trials.
also
share
perspectives
successful
accelerated
translation
integrated
healing.
Chemical Reviews,
Journal Year:
2024,
Volume and Issue:
124(2), P. 455 - 553
Published: Jan. 4, 2024
In
the
era
of
Internet-of-things,
many
things
can
stay
connected;
however,
biological
systems,
including
those
necessary
for
human
health,
remain
unable
to
connected
global
Internet
due
lack
soft
conformal
biosensors.
The
fundamental
challenge
lies
in
fact
that
electronics
and
biology
are
distinct
incompatible,
as
they
based
on
different
materials
via
functioning
principles.
particular,
body
is
curvilinear,
yet
typically
rigid
planar.
Recent
advances
design
have
generated
tremendous
opportunities
wearable
bioelectronics,
which
may
bridge
gap,
enabling
ultimate
dream
healthcare
anyone,
anytime,
anywhere.
We
begin
with
a
review
historical
development
healthcare,
indicating
significant
trend
healthcare.
This
followed
by
focal
point
discussion
about
new
design,
particularly
low-dimensional
nanomaterials.
summarize
material
types
their
attributes
designing
bioelectronic
sensors;
we
also
cover
synthesis
fabrication
methods,
top-down,
bottom-up,
combined
approaches.
Next,
discuss
energy
challenges
progress
made
date.
addition
front-end
devices,
describe
back-end
machine
learning
algorithms,
artificial
intelligence,
telecommunication,
software.
Afterward,
integration
systems
been
applied
various
testbeds
real-world
settings,
laboratories
preclinical
clinical
environments.
Finally,
narrate
remaining
conjunction
our
perspectives.
ACS Nano,
Journal Year:
2023,
Volume and Issue:
17(11), P. 9681 - 9693
Published: May 18, 2023
Hydrogels
have
emerged
as
promising
materials
for
flexible
electronics
due
to
their
unique
properties,
such
high
water
content,
softness,
and
biocompatibility.
In
this
perspective,
we
provide
an
overview
of
the
development
hydrogels
electronics,
with
a
focus
on
three
key
aspects:
mechanical
interfacial
adhesion,
conductivity.
We
discuss
principles
designing
high-performance
present
representative
examples
potential
applications
in
field
healthcare.
Despite
significant
progress,
several
challenges
remain,
including
improving
antifatigue
capability,
enhancing
balancing
content
wet
environments.
Additionally,
highlight
importance
considering
hydrogel-cell
interactions
dynamic
properties
future
research.
Looking
ahead,
is
promising,
exciting
opportunities
horizon,
but
continued
investment
research
necessary
overcome
remaining
challenges.
Chemical Reviews,
Journal Year:
2023,
Volume and Issue:
123(21), P. 12105 - 12134
Published: Oct. 23, 2023
With
the
advancements
in
materials
science
and
micro/nanoengineering,
field
of
wearable
electronics
has
experienced
a
rapid
growth
significantly
impacted
transformed
various
aspects
daily
human
life.
These
devices
enable
individuals
to
conveniently
access
health
assessments
without
visiting
hospitals
provide
continuous,
detailed
monitoring
create
comprehensive
data
sets
for
physicians
analyze
diagnose.
Nonetheless,
several
challenges
continue
hinder
practical
application
electronics,
such
as
skin
compliance,
biocompatibility,
stability,
power
supply.
In
this
review,
we
address
supply
issue
examine
recent
innovative
self-powered
technologies
electronics.
Specifically,
explore
sensors
systems,
two
primary
strategies
employed
field.
The
former
emphasizes
integration
nanogenerator
sensing
units,
thereby
reducing
overall
system
consumption,
while
latter
focuses
on
utilizing
sources
drive
entire
system.
Finally,
present
future
perspectives
