International Journal of Molecular Sciences,
Journal Year:
2020,
Volume and Issue:
21(8), P. 2809 - 2809
Published: April 17, 2020
This
pilot
study
aims
to
investigate
whether
salivary
small
extracellular
vesicle
(sEV)-associated
microRNAs
could
act
as
potential
biomarkers
for
periodontal
disease
status.
Twenty-nine
participants
(10
who
were
healthy,
nine
with
gingivitis,
10
stage
III/IV
periodontitis)
recruited
and
unstimulated
whole
saliva
samples
collected.
Salivary
sEVs
isolated
using
the
size-exclusion
chromatography
(SEC)
method
characterised
by
morphology,
EV-protein
size
distribution
transmission
electron
microscopy
(TEM),
Western
Blot
Nanoparticle
Tracking
Analysis
(NTA),
respectively.
Ten
mature
(miRNAs)
in
evaluated
RT-qPCR.
The
discriminatory
power
of
miRNAs
gingivitis
periodontitis
versus
healthy
controls
was
Receiver
Operating
Characteristics
(ROC)
curves.
comparable
mode,
particle
concentration
patients.
Compared
saliva,
three
significantly
increased
(hsa-miR-140-5p,
hsa-miR-146a-5p
hsa-miR-628-5p)
only
detected
when
compared
that
controls,
a
good
(area
under
curve
(AUC)
=
0.96)
diagnosis.
Our
demonstrated
are
non-invasive
source
Three
selectively
enriched
sEVs,
but
not
be
Scientific Reports,
Journal Year:
2020,
Volume and Issue:
10(1)
Published: April 30, 2020
Abstract
Environmental
pollution
arising
from
plastic
waste
is
a
major
global
concern.
Plastic
macroparticles,
microparticles,
and
nanoparticles
have
the
potential
to
affect
marine
ecosystems
human
health.
It
generally
accepted
that
microplastic
particles
are
not
harmful
or
at
best
minimal
However
direct
contact
with
may
possible
adverse
effect
in
cellular
level.
Primary
polystyrene
(PS)
were
focus
of
this
study,
we
investigated
impacts
these
microplastics
on
health
We
determined
PS
immune
stimulants
induced
cytokine
chemokine
production
size-dependent
concentration-dependent
manner.
Scientific Reports,
Journal Year:
2019,
Volume and Issue:
9(1)
Published: Jan. 31, 2019
Plastic
pollution
represents
a
pervasive
and
increasing
threat
to
marine
ecosystems
worldwide
there
is
need
better
understand
the
extent
which
microplastics
(<5
mm)
are
ingested
by
high
trophic-level
taxa,
such
as
mammals.
Here,
we
perform
comprehensive
assessment
examining
whole
digestive
tracts
of
50
individuals
from
10
species
whilst
operating
strict
contamination
controls.
Microplastics
were
ubiquitous
with
particles
detected
in
every
animal
examined.
The
relatively
low
number
per
(mean
=
5.5)
suggests
these
transitory.
Stomachs,
however,
found
contain
greater
than
intestines,
indicating
potential
site
temporary
retention.
majority
fibres
(84%)
while
remaining
16%
was
fragments.
Particles
mainly
blue
black
(42.5%
26.4%)
colour
Nylon
most
prevalent
(60%)
polymer
type.
A
possible
relationship
between
cause
death
category
microplastic
abundance,
that
animals
died
due
infectious
diseases
had
slightly
higher
those
trauma
other
drivers
mortality.
It
not
possible,
draw
any
firm
conclusions
on
biological
significance
this
observation
further
research
required
chronic
effects
exposure
health,
particularly
mammals
widely
considered
important
sentinels
for
implications
environment.
Frontiers in Human Neuroscience,
Journal Year:
2019,
Volume and Issue:
13
Published: March 19, 2019
As
driving
functions
become
increasingly
automated,
motorists
run
the
risk
of
becoming
cognitively
removed
from
process.
Psychophysiological
measures
may
provide
added
value
not
captured
through
behavioral
or
self-report
alone.
This
paper
provides
a
selective
review
psychophysiological
that
can
be
utilized
to
assess
cognitive
states
in
real-world
environments.
First,
importance
within
context
traffic
safety
is
discussed.
Next,
most
commonly
used
physiology-based
indices
are
considered
as
potential
candidates
relevant
for
research.
These
include:
electroencephalography
and
event-related
potentials,
optical
imaging,
heart
rate
variability,
blood
pressure,
skin
conductance,
electromyography,
thermal
pupillometry.
For
each
these
measures,
an
overview
provided,
followed
by
discussion
methods
measuring
it
context.
Drawing
recent
empirical
psychophysiology
research,
relative
strengths
limitations
measure
discussed
highlight
measures'
unique
value.
Challenges
recommendations
valid
reliable
quantification
lab
(less
predictable)
settings
considered.
Finally,
we
discuss
better
near
real-time
assessment
motorists'
applied
outside
lab.
synthesizes
literature
on
in-vehicle
advance
development
effective
human-machine
interfaces
driver
support
systems.
Frontiers in Psychology,
Journal Year:
2019,
Volume and Issue:
10
Published: Nov. 1, 2019
In
general,
it
is
well-recognized
that
both
acute
physical
exercises
and
regular
training
influence
brain
plasticity
cognitive
functions
positively.
However,
growing
evidence
shows
the
same
induce
very
heterogeneous
outcomes
across
individuals.
an
attempt
to
better
understand
this
interindividual
heterogeneity
in
response
exercising,
most
research,
so
far,
has
focused
on
non-modifiable
factors
such
as
sex
different
genotypes,
while
relatively
little
attention
been
paid
exercise
prescription
a
modifiable
factor.
With
adapted
dosage
can
be
made
comparable
individuals,
procedure
which
necessary
dose-response
relationship
exercise-cognition
research.
This
improved
understanding
of
relationships
could
help
design
more
efficient
approaches
against,
for
instance,
decline.
Brain Sciences,
Journal Year:
2021,
Volume and Issue:
11(2), P. 221 - 221
Published: Feb. 11, 2021
Our
access
to
computer-generated
worlds
changes
the
way
we
feel,
how
think,
and
solve
problems.
In
this
review,
explore
utility
of
different
types
virtual
reality,
immersive
or
non-immersive,
for
providing
controllable,
safe
environments
that
enable
individual
training,
neurorehabilitation,
even
replacement
lost
functions.
The
neurobiological
effects
reality
on
neuronal
plasticity
have
been
shown
result
in
increased
cortical
gray
matter
volumes,
higher
concentration
electroencephalographic
beta-waves,
enhanced
cognitive
performance.
Clinical
application
is
aided
by
innovative
brain–computer
interfaces,
which
allow
direct
tapping
into
electric
activity
generated
brain
areas
precise
voluntary
control
connected
robotic
devices.
Virtual
also
valuable
healthy
individuals
as
a
narrative
medium
redesigning
their
stories
an
integrative
process
self-improvement
personal
development.
Future
upgrades
reality-based
technologies
promise
help
humans
transcend
limitations
biological
bodies
augment
capacity
mold
physical
better
meet
needs
globalized
world.
Virtual Reality,
Journal Year:
2022,
Volume and Issue:
27(1), P. 19 - 50
Published: July 16, 2022
Abstract
This
narrative
review
synthesizes
and
introduces
386
previous
works
about
virtual
reality-induced
symptoms
effects
by
focusing
on
cybersickness,
visual
fatigue,
muscle
acute
stress,
mental
overload.
Usually,
these
VRISE
are
treated
independently
in
the
literature,
although
reality
is
increasingly
considered
an
option
to
replace
PCs
at
workplace,
which
encourages
us
consider
them
all
once.
We
emphasize
context
of
office-like
tasks
VR,
gathering
57
articles
meeting
our
inclusion/exclusion
criteria.
Cybersickness
symptoms,
influenced
fifty
factors,
could
prevent
workers
from
using
VR.
It
studied
but
requires
more
research
reach
a
theoretical
consensus.
VR
can
lead
fatigue
than
other
screen
uses,
fifteen
mainly
due
vergence-accommodation
conflicts.
side
effect
testing
clarification
how
it
differs
cybersickness.
provoke
musculoskeletal
discomfort,
depending
interactions.
stress
technostress,
task
difficulty,
time
pressure,
public
speaking.
also
potentially
leads
overload,
load,
intrinsically
interaction
interface
environment.
propose
agenda
tackle
ergonomics
risks
issues
workplace.
Reliability Engineering & System Safety,
Journal Year:
2023,
Volume and Issue:
233, P. 109103 - 109103
Published: Jan. 18, 2023
Human
errors
significantly
contribute
to
transport
accidents.
performance
measurement
(HPM)
is
crucial
ensure
human
reliability
and
reduce
errors.
However,
how
address
the
subjective
bias
introduced
by
assessors
in
HPM
seafarer
certification
remains
a
key
research
challenge.
This
paper
aims
develop
new
psychophysiological
data-driven
machine
learning
method
realize
effective
maritime
sector.
It
conducts
experiments
using
functional
Near-Infrared
Spectroscopy
(fNIRS)
technology
compares
of
two
groups
case
(i.e.
experienced
inexperienced
seafarers
terms
different
qualifications
certificates),
via
an
Artificial
Neural
Network
(ANN)
model.
The
results
have
generated
insightful
implications
contributions,
including
(1)
introduction
objective
criterion
for
monitor,
assess,
support
training
authorities;
(2)
quantification
response
under
specific
missions,
which
serves
as
index
shipping
company
evaluate
reliability;
(3)
supportive
tool
complex
emerging
systems
(e.g.
Maritime
Autonomous
Surface
Ship
(MASS))
design
ship
manufactures
shipbuilders.
Sensors,
Journal Year:
2024,
Volume and Issue:
24(3), P. 977 - 977
Published: Feb. 2, 2024
Spatial
cognition
plays
a
crucial
role
in
academic
achievement,
particularly
science,
technology,
engineering,
and
mathematics
(STEM)
domains.
Immersive
virtual
environments
(VRs)
have
the
growing
potential
to
reduce
cognitive
load
improve
spatial
reasoning.
However,
traditional
methods
struggle
assess
mental
effort
required
for
visuospatial
processes
due
difficulty
verbalizing
actions
other
limitations
self-reported
evaluations.
In
this
neuroergonomics
study,
we
aimed
capture
neural
activity
associated
with
workload
during
tasks
evaluate
impact
of
visualization
medium
on
task
performance.
We
utilized
functional
near-infrared
spectroscopy
(fNIRS)
wearable
neuroimaging
spatial-reasoning-based
problem-solving
compared
VR,
computer
screen,
physical
real-world
presentation.
Our
results
reveal
higher
efficiency
prefrontal
cortex
(PFC)
3D
geometry
puzzles
VR
settings
world
screen.
appears
by
facilitating
providing
visual
cues.
This
makes
it
valuable
tool
training,
especially
beginners.
Additionally,
our
multimodal
approach
allows
progressively
increasing
complexity,
maintaining
challenge
throughout
training.
study
underscores
developing
skills
highlights
value
comparing
brain
data
human
interaction
across
different
training
settings.
Frontiers in Psychology,
Journal Year:
2018,
Volume and Issue:
9
Published: Sept. 5, 2018
One
of
the
most
pleasurable
aspects
video
games
is
their
ability
to
induce
immersive
experiences.
However,
there
appears
be
a
tentative
conceptualization
what
an
experience
is.
In
this
short
review,
we
specifically
focus
on
terms
flow
and
immersion,
as
they
are
widely
used
applied
definitions
in
game
literature,
whilst
differences
remain
disputable.
We
critically
review
concepts
separately
proceed
with
comparison
proposed
differences.
conclude
that
immersion
do
not
substantially
differ
current
studies
more
evidence
needed
justify
separation.