Severe Hypoxia Does Not Offset the Benefits of Exercise on Cognitive Function in Sedentary Young Women DOI Open Access

On-Kei Lei,

Zhaowei Kong, Paul D. Loprinzi

et al.

International Journal of Environmental Research and Public Health, Journal Year: 2019, Volume and Issue: 16(6), P. 1003 - 1003

Published: March 20, 2019

Purpose: To examine the effect of acute moderate-intensity continuous exercise performed under normobaric severe hypoxia on cognition, compared to sea-level normoxia. Methods: Thirty healthy inactive women randomly two experimental trials separated by at least three days but approximately same time day. Executive functions were measured during follicular stage via an interference control task before (rest) and with 45% peak power output normoxia (PIO₂ = 150 mmHg, FIO₂ 0.21), (2) 87 0.12, simulated altitude 4000 m). Reaction (RT), accuracy rate (AC), heart rate, ratings perceived exertion, peripheral oxygen saturation (SpO₂) collected exercise. Results: RT (p < 0.05, η²p 0.203) decreased moderate when rest, while a short bout improved 0.134). Exercise had no effects AC > 0.05). No significant associations found between changes SpO₂ conditions Conclusions: At phase menstrual cycle, m caused impairment rest. ameliorated in hypoxia, suggesting that both short-term have benefits cognitive function sedentary young women.

Language: Английский

The effects of mental fatigue on sport-related performance DOI
Benjamin Pageaux, Romuald Lepers

Progress in brain research, Journal Year: 2018, Volume and Issue: unknown, P. 291 - 315

Published: Jan. 1, 2018

Language: Английский

Citations

180
The neuromodulatory role of dopamine in improved reaction time by acute cardiovascular exercise DOI
Soichi Ando,

Toshihiko Fujimoto,

Mizuki Sudo

et al.

The Journal of Physiology, Journal Year: 2024, Volume and Issue: 602(3), P. 461 - 484

Published: Jan. 2, 2024

Abstract Acute cardiovascular physical exercise improves cognitive performance, as evidenced by a reduction in reaction time (RT). However, the mechanistic understanding of how this occurs is elusive and has not been rigorously investigated humans. Here, using positron emission tomography (PET) with [ 11 C]raclopride, multi‐experiment study we whether acute releases endogenous dopamine (DA) brain. We hypothesized that augments brain DA system, RT improvement correlated release. The PET (Experiment 1: n = 16) demonstrated released DA, release was improvements Go/No‐Go task. Thereafter, two electrical muscle stimulation (EMS) studies (Experiments 2 3: 18 22 respectively), what triggers improvement. EMS indicated moderate arm cranking improved RT, but following alone or combined no load cranking. novel findings from these experiments are: (1) appears to be an important neuromodulator for (2) only altered when associated central signals higher centres. Our explain humans rapidly alter their behaviour neuromodulatory systems have significant implications promotion health. image Key points Using neurochemical specificity C]raclopride tomography, supine cycling (DA), RT. Additional peripherally driven contractions (i.e. exercise) were insufficient improve current suggests improvement,

Language: Английский

Citations

18
Effect of Exercise on Brain Health: The Potential Role of Lactate as a Myokine DOI Creative Commons
Takeshi Hashimoto, Hayato Tsukamoto, Soichi Ando

et al.

Metabolites, Journal Year: 2021, Volume and Issue: 11(12), P. 813 - 813

Published: Nov. 29, 2021

It has been well established in epidemiological studies and randomized controlled trials that habitual exercise is beneficial for brain health, such as cognition mental health. Generally, it may be reasonable to say the physiological benefits of acute can prevent disorders late life if habitually/chronically conducted. However, mechanisms improvement function via chronic remain incompletely understood because are assumed multifactorial, adaptation repeated exercise. This review postulates cerebral metabolism an important factor determines function. Among metabolites, provision lactate meet elevated neural activity regulate cerebrovascular system redox states response responsible exercise-enhanced Here, we summarize current knowledge regarding influence on particularly cognitive performance, with underlying by means lactate. Regarding function, relevance intensity modality, high-intensity interval exercise, acknowledged induce “metabolic myokine” (i.e., lactate)

Language: Английский

Citations

68
The interactive effects of acute exercise and hypoxia on cognitive performance: A narrative review DOI
Soichi Ando, Takaaki Komiyama,

Mizuki Sudo

et al.

Scandinavian Journal of Medicine and Science in Sports, Journal Year: 2019, Volume and Issue: 30(3), P. 384 - 398

Published: Oct. 12, 2019

Acute moderate intensity exercise has been shown to improve cognitive performance. In contrast, hypoxia is believed impair The detrimental effects of on performance are primarily dependent the severity and duration exposure. this review, we describe how acute under alters performance, propose that combined mainly determined by interaction among duration, hypoxia, exposure hypoxia. We discuss physiological mechanism(s) suggest alterations in neurotransmitter function, cerebral blood flow, possibly metabolism primary candidates determine when with Furthermore, acclimatization appears counteract impaired during prolonged although precise responsible for amelioration remain be elucidated. This review implications sporting, occupational, recreational activities at terrestrial high altitude where essential. Further studies required understand mechanisms performed

Language: Английский

Citations

64
The effects of acute high-intensity aerobic exercise on cognitive performance: A structured narrative review DOI Creative Commons

Mizuki Sudo,

Joseph T. Costello, Terry McMorris

et al.

Frontiers in Behavioral Neuroscience, Journal Year: 2022, Volume and Issue: 16

Published: Sept. 23, 2022

It is well established that acute moderate-intensity exercise improves cognitive performance. However, the effects of high-intensity aerobic on performance have not been characterized. In this review, we summarize literature investigating exercise-cognition interaction, especially focusing exercise. We discuss methodological and physiological factors potentially mediate in response to propose are primarily affected by timing task (during vs. after exercise, time delay exercise). particular, more likely be impaired during when both demands high completed simultaneously (i.e., dual-task paradigm). The may also type task, physical fitness, mode/duration, age. Second, suggest interactions between changes regional cerebral blood flow (CBF), oxygenation, metabolism, neuromodulation neurotransmitters/neurotrophic factors, a variety psychological promising candidates determine present review has implications for recreational, sporting, occupational activities where required concurrently.

Language: Английский

Citations

37
Cognitive performance is associated with cerebral oxygenation and peripheral oxygen saturation, but not plasma catecholamines, during graded normobaric hypoxia DOI Open Access
Thomas B. Williams, Jo Corbett, Terry McMorris

et al.

Experimental Physiology, Journal Year: 2019, Volume and Issue: 104(9), P. 1384 - 1397

Published: June 13, 2019

What is the central question of this study? are mechanisms responsible for decline in cognitive performance following exposure to acute normobaric hypoxia? main findings and their importance? We found that (1) a complex executive task (n-back) was reduced at FIO2 0.12; (2) there strong correlation between n-back reductions SpO2 cerebral oxygenation; (3) plasma adrenaline, noradrenaline, cortisol copeptin were not correlated with performance.It well established hypoxia impairs function; however, physiological these effects have received relatively little attention. This study examined graded fraction inspired oxygen ( ) on saturation ), oxygenation, cardiorespiratory variables, activity sympathoadrenal system (adrenaline, noradrenaline) hypothalamic-pituitary-adrenal axis (cortisol, copeptin), performance. Twelve healthy males [mean (SD), age: 22 (4) years, height: 178 (5) cm, mass: 75 (9) kg, FEV1 /FVC ratio: 85 (5)%] completed four-task battery tests examine inhibition, selective attention (Eriksen flanker), function simple choice reaction time (Deary-Liewald). Tests before 60 min 0.2093, 0.17, 0.145 0.12. Following exposure, response accuracy significantly 0.12 compared baseline [82 vs. 93 (5)%; P < 0.001] all other conditions same point [ 0.2093: 92 (3)%; 0.17: 91 (6)%; 0.145: (10)%; 12: 82 (9)%; 0.05]. The tasks maintained. Δaccuracy Δreaction both Δ [r(9) = 0.66, 0.001 r(9) -0.36, 0.037, respectively] Δcerebral oxygenation [r(7) 0.55, r(7) -0.38, 0.045, respectively]. Plasma elevated any condition or These suggest peripheral increased axis, as previously speculated, decrease during hypoxia.

Language: Английский

Citations

52
Does exercise have a protective effect on cognitive function under hypoxia? A systematic review with meta-analysis DOI Creative Commons
Myungjin Jung, Liye Zou, Jane Jie Yu

et al.

Journal of sport and health science/Journal of Sport and Health Science, Journal Year: 2020, Volume and Issue: 9(6), P. 562 - 577

Published: April 20, 2020

This study aimed to examine (1) the independent effects of hypoxia on cognitive function and (2) exercise cognition while under hypoxia.

Language: Английский

Citations

49
A Review of Cognitive Changes During Acute Aerobic Exercise DOI Creative Commons
Julie A. Cantelon, Grace E. Giles

Frontiers in Psychology, Journal Year: 2021, Volume and Issue: 12

Published: Dec. 16, 2021

A growing body of work has investigated the effects acute, or single bouts of, aerobic exercise on cognitive function. However, review this research largely focused changes following exercise, with less focus during exercise. The purpose is to discuss critical characteristics literature date, including: (1) what been done, (2) found, and (3) next. Furthermore, previous meta-analytic reviews have demonstrated there a small positive effect cognition when measured executive functions showing largest effects. these group together. Here we explore how inhibition, working memory flexibility are individually impacted by factors such as intensity duration. Searches electronic databases reference lists from relevant studies resulted in 73 meeting inclusion criteria. Studies were grouped non-executive domains, duration bouts. Within domain, found that remain mixed, inhibition clearer. Moderate improves response time, vigorous impairs accuracy. time across domains attention, motor speed information processing, no significant Memory processes consistently improved Effects accuracy nuanced vary domain. typically durations 45 min less, extended unexplored. We highlight consider assessing exercise-cognition relationships, well current gaps future directions for field.

Language: Английский

Citations

40
High-Altitude Cognitive Impairment Is Prevented by Enriched Environment Including Exercise via VEGF Signaling DOI Creative Commons

Christina Koester-Hegmann,

Harkaitz Bengoetxea, Dmitry Kosenkov

et al.

Frontiers in Cellular Neuroscience, Journal Year: 2019, Volume and Issue: 12

Published: Jan. 9, 2019

Exposure to hypobaric hypoxia at high altitude (above 2500 m asl) causes cognitive impairment, mostly attributed changes in brain perfusion and consequently neuronal death. Enriched environment voluntary exercise has been shown improve function, enhance microvasculature neurogenesis, be neuroprotective. Here we show that high-altitude exposure (3540 of Long Evans rats during early adulthood (P48-P59) increases neurogenesis but impairs spatial visual memory along with an increase apoptosis. We tested whether enriched including a running wheel for (EE) can prevent impairment apoptosis is prevented. found EE retained altitude, prevented Further, vascular endothelial growth factor (VEGF) signaling required the EE-mediated recovery reduction Pharmacological inhibition VEGF by oral application tyrosine kinase inhibitor (Vandetanib) animals housed EE, neurogenesis. Surprisingly, also caused EE-housed reared low affecting mainly dentate gyrus not conclude neuroprotective essential maintenance cognition exposure, altitude. Finally, our data underlines potential risk disturbed adaption from use VEGF-signaling inhibitors therapeutic purposes.

Language: Английский

Citations

37
Mechanism, prevention and treatment of cognitive impairment caused by high altitude exposure DOI Creative Commons
Xin Chen, J K Zhang, Yuan Lin

et al.

Frontiers in Physiology, Journal Year: 2023, Volume and Issue: 14

Published: Sept. 4, 2023

Hypobaric hypoxia (HH) characteristics induce impaired cognitive function, reduced concentration, and memory. In recent years, an increasing number of people have migrated to high-altitude areas for work study. Headache, sleep disturbance, impairment from HH, severely challenges the physical mental health affects their quality life efficiency. This review summarizes manifestations, mechanisms, preventive therapeutic methods HH environment affecting function provides theoretical references exploring treating high altitude-induced impairment.

Language: Английский

Citations

13