Assessment of wastewater-borne pharmaceuticals in tissues and body fluids from riverine fish DOI Creative Commons
Diana P. Manjarrés-López, J.M. Peña-Herrera, Lluís Benejam

et al.

Environmental Pollution, Journal Year: 2023, Volume and Issue: 324, P. 121374 - 121374

Published: Feb. 27, 2023

Riverine fish in densely populated areas is constantly exposed to wastewater-borne contaminants from effluent discharges. These can enter the organism through skin, gills or by ingestion. Whereas most studies assessing contaminant burden have focused either on muscle a limited set of tissues. Here we out generate more comprehensive overview distribution pollutants across tissues analyzing panel matrices including liver, kidney, brain, muscle, heart, plasma and bile. To achieve broad analyte coverage with minimal bias towards specific class, sample extracts four species were analyzed High-Performance Liquid Chromatography (HPLC) - high-resolution mass spectrometry (HRMS) for presence 600 pharmaceutically active compounds (PhACs) known environmental relevance river water suspect-screening analysis. A total 30 detected suspect screening at least one clear prevalence antidepressants. Of these, 15 confidence level 2.a (Schymanski scale), 1 following confirmation authentic standards, which furthermore enabled their quantification. The PhACs confirmed included acridone, acetaminophen, caffeine, clarithromycin, codeine, diazepam, diltiazem, fluoxetine, ketoprofen, loratadine, metoprolol, sertraline, sotalol, trimethoprim, venlafaxine. Among these substances, sertraline stood as it displayed highest detection frequency. values tissue partition coefficients brain correlated its physicochemical properties. Based inter-matrix comparison frequencies, skin heart should be biomonitoring riverine fish.

Language: Английский

Abundance, fate, and effects of pharmaceuticals and personal care products in aquatic environments DOI Creative Commons
Adeyemi S. Adeleye, Jie Xue, Yixin Zhao

et al.

Journal of Hazardous Materials, Journal Year: 2021, Volume and Issue: 424, P. 127284 - 127284

Published: Sept. 22, 2021

Pharmaceuticals and personal care products (PPCPs) are found in wastewater, thus, the environment. In this study, current knowledge about occurrence fate of PPCPs aquatic systems-including wastewater treatment plants (WWTPs) natural waters around world-is critically reviewed to inform state science highlight existing gaps. Excretion by humans is primary route entry into municipal systems, but significant contributions also occur through emissions from hospitals, manufacturers, agriculture. Abundance raw influenced several factors, including population density demography served WWTPs, presence hospitals drugs manufacturers sewershed, disease burden served, local regulations, climatic conditions. Based on data obtained analgesics, antibiotics, stimulants (e.g., caffeine) most abundant wastewater. conventional removal occurs during secondary treatment, overall exceeds 90% for treatable PPCPs. Regardless, total PPCP mass discharged with effluent an average WWTP receiving (7.35-20,160 g/day) still considerable, because potential adverse effects some (such as ibuprofen) organisms within measured concentrations surface waters.

Language: Английский

Citations

262
Fate and toxicity of pharmaceuticals in water environment: An insight on their occurrence in South Asia DOI
Hudda Khaleeq Khan, Muhammad Yasir Abdur Rehman, Riffat Naseem Malik

et al.

Journal of Environmental Management, Journal Year: 2020, Volume and Issue: 271, P. 111030 - 111030

Published: July 2, 2020

Language: Английский

Citations

172
Occurrence, transformation, bioaccumulation, risk and analysis of pharmaceutical and personal care products from wastewater: a review DOI Creative Commons

Uttpal Anand,

Bashir Adelodun, Carlo Cabreros

et al.

Environmental Chemistry Letters, Journal Year: 2022, Volume and Issue: 20(6), P. 3883 - 3904

Published: Aug. 17, 2022

Abstract Almost all aspects of society from food security to disease control and prevention have benefited pharmaceutical personal care products, yet these products are a major source contamination that ends up in wastewater ecosystems. This issue has been sharply accentuated during the coronavirus pandemic 2019 (COVID-19) due higher use disinfectants other products. Here we review with focus on their occurrence environment, detection, risk, removal.

Language: Английский

Citations

109
Pharmaceuticals and personal care products as emerging contaminants: Need for combined treatment strategy DOI Creative Commons

Justice Obinna Osuoha,

Brilliance Onyinyechi Anyanwu, Chisom Ejileugha

et al.

Journal of Hazardous Materials Advances, Journal Year: 2022, Volume and Issue: 9, P. 100206 - 100206

Published: Nov. 21, 2022

Pharmaceuticals and personal care products (PPCPs) are distinct group of chemicals, specifically referred to as emerging environmental contaminants because their intrinsic capacity trigger diverse physiological effects in humans. Numerous research investigations have confirmed the existence PPCPs matrices, which provokes worry about prospective severe implications biodiversity For this reason, manuscript reviews present state-of-the-art information on aquatic environment. The environment risk associated with abundance was established based occurrence, toxicity, bioaccumulation. Existing regarding sources, migration, degradation these provided. Subsequently, a comprehensive concerning global concentration also Carbamazepine appears be most persistent judging from reports literature different treatment strategies. A combined strategy is recommended for improved removal efficiency media especially PPCPs. combination microbial other technologies will effective eradication.

Language: Английский

Citations

91
Photocatalytic degradation of acetaminophen using a novel TiO2-orange peel-derived biochar composite: Synthesize, characterization and optimization of key factors DOI

Mohammad Sina Mohtaram,

Soheil Mohtaram, Samad Sabbaghi

et al.

Journal of Water Process Engineering, Journal Year: 2024, Volume and Issue: 58, P. 104884 - 104884

Published: Jan. 28, 2024

Language: Английский

Citations

25
First nationwide investigation and environmental risk assessment of 72 pharmaceuticals and personal care products from Sri Lankan surface waterways DOI
Keerthi S. Guruge, Prasun Goswami, Rumi Tanoue

et al.

The Science of The Total Environment, Journal Year: 2019, Volume and Issue: 690, P. 683 - 695

Published: July 4, 2019

Language: Английский

Citations

128
Distribution and Chemical Analysis of Pharmaceuticals and Personal Care Products (PPCPs) in the Environmental Systems: A Review DOI Open Access
Chinemerem Ruth Ohoro, Abiodun Olagoke Adeniji, Anthony I. Okoh

et al.

International Journal of Environmental Research and Public Health, Journal Year: 2019, Volume and Issue: 16(17), P. 3026 - 3026

Published: Aug. 21, 2019

PPCPs are found almost everywhere in the environment especially at an alarming rate and very low concentration aquatic systems. Many methods—including pressurized hot water extraction (PHWE), liquid (PLE), ultrasound-assisted (UAE), micro-assisted (MAE)—have been employed for their from both surface waters biota. Solid-phase (SPE) proved to be best method these polar, non-volatile, thermally unstable compounds water. However, ultrasonic works better isolation sediment because it is cheap consumes less solvent, even though SPE preferred as a clean-up samples. groups of—acidic (e.g., diclofenac, ibuprofen, naproxen), neutral caffeine, carbamazepine, fluoxetine), basic pharmaceuticals, well antibiotics estrogens amongst others. which present trace levels (ng/L) more often determined by chromatography-mass spectrometry (LC-MS), gas (GC-MS), high-performance chromatography-ultraviolent (HPLC-UV). Of these, LC-MS LC-MS-MS mostly analysis of this class compounds, not without draw-back matrix effect. GC-MS GC-MS-MS considered alternative cost-effective methods that can also give results after derivatization.

Language: Английский

Citations

114
Occurrence of pharmaceuticals in the environmental waters: African and Asian perspectives DOI Creative Commons
Ngwako Joseas Waleng, Philiswa N. Nomngongo

Environmental Chemistry and Ecotoxicology, Journal Year: 2021, Volume and Issue: 4, P. 50 - 66

Published: Dec. 3, 2021

Environmental ubiquity of pharmaceuticals has stimulated a lot societal and global concerns. The occurrence in the environment differs from country to depending on extent consumption monitoring. Most studies reporting are conducted coastal regions with numerous articles reviews reported developed countries. current review reports inland waters major focus devoted developing countries Africa Asia. was further dedicated sources distribution mechanisms, which contribute greatly their environment. Antibiotics non-steroidal anti-inflammatory drugs (NSAIDs) most African waters. For example, an antibiotic (sulfamethoxazole) detected more than four highest concentrations reaching 53.8–56.6 μg L−1 Kenya Mozambique. Furthermore, amoxicillin ranging 0.087–272.2 were Nigeria. Ibuprofen, is NSAID at 67.9 58.7 Durban city Msunduzi River (KwaZulu-Natal, South Africa), respectively. However, concentration antiretroviral drug (lamivudine) up 167 found surface water samples collected Nairobi Kisumu city, Kenya. In Asian countries, antibiotics 365.05 samples. other comparably below environmental Health risks associated fate critically reviewed. Sample preparation techniques analytical instruments necessary for also concluding remarks based deliberating possible future prospects within research expertise.

Language: Английский

Citations

92
Pharmaceutical and Personal Care Products in Different Matrices: Occurrence, Pathways, and Treatment Processes DOI Open Access

Nash Jett Reyes,

Franz Kevin F. Geronimo,

K.A.V. Yano

et al.

Water, Journal Year: 2021, Volume and Issue: 13(9), P. 1159 - 1159

Published: April 22, 2021

The procedures for analyzing pharmaceuticals and personal care products (PPCPs) are typically tedious expensive thus, it is necessary to synthesize all available information from previously conducted research. An extensive collection of PPCP data the published literature was compiled determine occurrence, pathways, effectiveness current treatment technologies removal PPCPs in water wastewater. Approximately 90% papers originated Asia, Europe, North American regions. incomplete different wastewater processes widely reported, thus resulting occurrence compounds various environmental compartments. Caffeine, carbamazepine, diclofenac, ibuprofen, triclosan, triclocarban were among most commonly reported detected solid matrices. Trace concentrations also on plants animal tissues, indicating bioaccumulative properties some compounds. A significant lack studies regarding presence plant samples identified review. Furthermore, there still knowledge gaps ecotoxicity, sub-lethal effects, effective PPCPs. this study can be used devise a more research paradigm guidelines management.

Language: Английский

Citations

87
Pharmaceuticals and personal care products in aquatic environments and their removal by algae-based systems DOI
Amin Mojiri, John L. Zhou, Harsha Ratnaweera

et al.

Chemosphere, Journal Year: 2021, Volume and Issue: 288, P. 132580 - 132580

Published: Oct. 21, 2021

Language: Английский

Citations

69