Elsevier eBooks, Journal Year: 2021, Volume and Issue: unknown, P. 139 - 163
Published: Oct. 15, 2021
Language: Английский
Food Chemistry, Journal Year: 2021, Volume and Issue: 375, P. 131885 - 131885
Published: Dec. 17, 2021
Language: Английский
Citations
200
Journal of Controlled Release, Journal Year: 2023, Volume and Issue: 355, P. 327 - 342
Published: Feb. 9, 2023
Language: Английский
Citations
62
ACS Biomaterials Science & Engineering, Journal Year: 2021, Volume and Issue: 7(8), P. 3886 - 3897
Published: July 14, 2021
Chronic wounds have become a major health problem worldwide. Curcumin (Cur), with strong anti-inflammatory and anti-infective properties, is introduced as unique molecule for wound dressing applications. In the present study, Cur-loaded chitosan/poly(ethylene oxide)/collagen (Cho/PEO/Col) nanofibers were developed applications by blend–electrospinning process. Structural, mechanical, biological properties of evaluated using SEM, FTIR, tensile testing, in vitro release Alamar blue cytotoxicity assay, vivo study rat model. According to results, Cur was successfully released up 3 days without any significant above hybrid human dermal fibroblasts. studies on full-thickness model indicated improvement mean area closure applying Cho/PEO/Col nanofibers. The electrospun loaded could be considered promising type wound-healing
Language: Английский
Citations
90
ACS Applied Materials & Interfaces, Journal Year: 2021, Volume and Issue: 13(35), P. 41372 - 41395
Published: Aug. 27, 2021
While antioxidants are widely known as natural components of healthy food and drinks or additives to commercial polymer materials prevent their degradation, recent years have seen increasing interest in enhancing the antioxidant functionality newly developed coatings. This paper provides a critical overview comparative analysis multiple ways integrating within diverse materials, including bulk films, electrospun fibers, self-assembled Polyphenolic moieties with varied molecular architecture focus this Review, because abundance, nontoxic nature, potent activity. Polymer integrated polyphenolic offer opportunities challenges that span from fundamentals applications. In addition traditional blending developments surface grafting assembly via noncovalent interaction for controlling localization versus migration molecules discussed. The versatile chemistry offers numerous possibilities programmed inclusion these using not only van der Waals interactions covalent tethering polymers, but also hydrogen-bonding neutral molecules. An understanding rational use polyphenol surrounding can enable precise control concentration retention delivery rate packaging, biomedical, environmental
Language: Английский
Citations
76
Industrial Crops and Products, Journal Year: 2022, Volume and Issue: 186, P. 115250 - 115250
Published: June 29, 2022
Language: Английский
Citations
64
Molecules, Journal Year: 2022, Volume and Issue: 27(20), P. 6854 - 6854
Published: Oct. 13, 2022
Curcumin (CCM) is one of the most frequently explored plant compounds with various biological actions such as antibacterial, antiviral, antifungal, antineoplastic, and antioxidant/anti-inflammatory properties. The laboratory data clinical trials have demonstrated that bioavailability bioactivity curcumin are influenced by feature molecular complex types. has a high capacity to form complexes proteins (such whey proteins, bovine serum albumin, β-lactoglobulin), carbohydrates, lipids, natural (e.g., resveratrol, piperine, quercetin). These increase curcumin. current review provides these derivatization strategies for in terms physico-chemical aspects strong focus on different type characterization methods, thermodynamic features protein–curcumin complexes, aim evaluating best performances. literature offers, taking into consideration effects CCM, whole approach CCM-biomolecules interactions CCM-proteins, CCM-nanomaterials, CCM-natural regarding improve well systems.
Language: Английский
Citations
50
Foods, Journal Year: 2022, Volume and Issue: 11(22), P. 3709 - 3709
Published: Nov. 18, 2022
As an important food crop, corn has impact on people’s lives. The processing of produces many by-products, such as gluten meal, husk, and steep liquor, which are rich in protein, oil, carbohydrates, other nutrients, all inexpensive. Their accumulation large quantities during the production process not only results a burden environment but also loss potentially valuable materials that can be processed. In fact, by-products have been partially used functional foods, feed, industries. There is no doubt secondary utilization these solve problem waste pollution caused by them, produce high value-added products improve economic benefits corn. This paper describes detail higher-value five main by-products: husks, germ, fuel ethanol by-product. status was discussed roundly, development trend China countries analyzed, provided reference for deep industry.
Language: Английский
Citations
48
International Journal of Pharmaceutics, Journal Year: 2024, Volume and Issue: 661, P. 124341 - 124341
Published: June 15, 2024
Language: Английский
Citations
15
BMC Complementary Medicine and Therapies, Journal Year: 2024, Volume and Issue: 24(1)
Published: Jan. 25, 2024
Abstract Aims Thymus plant is a very useful herbal medicine with various properties such as anti-inflammatory and antibacterial. Therefore, the of this have made drug suitable candidate for wound healing. In study, hydroxypropyl methylcellulose (HPMC) gel containing Zataria multiflora volatile oil nanoemulsion (neZM) along polycaprolactone/chitosan (PCL-CS) nanofibrous scaffold was used, effect three experimental groups on healing process evaluated. The first group, HPMC neZM, second PCL-CS nanofibers, third neZM bandaged nanofibers (PCL-CS/neZM). Wounds common sterile gas were considered control. Methods synthesized by spontaneous method loaded into gel. DLS test investigated size these nanoemulsions. A also electrospinning then SEM contact angle tests morphology hydrophilicity/hydrophobicity its surface. animal study performed full-thickness skin wounds in rats, tissue regeneration control evaluated H&E Masson's trichrome staining. Results results showed that has 225±9 nm an acceptable dispersion. show non-beaded smooth fibers due to presence chitosan hydrophilic properties, higher surface hydrophobicity than PCL fibers. PCL-CS/neZM group significantly reduced compared other 7th, 14th, 21st days. histological could reduce parameters edema, inflammation, vascularity increase fibrosis, re-epithelialization, collagen deposition day 21. Conclusion treatment can effectively improve
Language: Английский
Citations
9
Heliyon, Journal Year: 2024, Volume and Issue: 10(11), P. e32566 - e32566
Published: June 1, 2024
In recent years, there has been a notable surge in the development of engineered bone scaffolds intended for repair defects. While autografts and allografts have traditionally served as primary methods tissue engineering, their inherent limitations spurred exploration novel avenues biomedical implant development. The emergence not only facilitates reconstruction but also offers platform targeted delivery therapeutic agents. There exists pervasive interest leveraging various drugs, proteins, growth factors, biomolecules with osteogenic properties to augment formation, enduring side effects associated current clinical modalities necessitate pursuit safer alternatives. Curcumin, principal bioactive compound found turmeric, demonstrated efficacy regulating proliferation differentiation cells while promoting formation. Nevertheless, its utility is hindered by restricted water solubility poor bioavailability. Strategies aimed at enhancing solubility, stability, bioavailability curcumin, including formulation techniques such liposomes nanoparticles or complexation metals, explored. This investigation dedicated exploring impact curcumin on proliferation, differentiation, migration osteocytes, osteoblasts, osteoclasts.
Language: Английский
Citations
9