Journal of Functional Biomaterials,
Journal Year:
2024,
Volume and Issue:
15(3), P. 73 - 73
Published: March 17, 2024
The
cost
of
treatment
antibiotic-resistant
pathogens
is
on
the
level
tens
billions
dollars
at
moment.
It
special
interest
to
reduce
or
solve
this
problem
using
antimicrobial
coatings,
especially
in
hospitals
other
healthcare
facilities.
bacteria
can
transfer
from
medical
staff
contaminated
surfaces
patients.
In
paper,
we
focused
our
attention
antibacterial
and
antibiofouling
activities
two
types
photodynamic
polyurethane
composite
films
doped
with
carbon
polymerized
dots
(CPDs)
fullerene
C60.
Detailed
atomic
force,
electrostatic
force
viscoelastic
microscopy
revealed
topology,
nanoelectrical
nanomechanical
properties
used
fillers
composites.
A
relationship
between
electronic
structure
nanocarbon
composites
was
established.
Thorough
spectroscopic
analysis
reactive
oxygen
species
(ROS)
generation
conducted
for
both
films,
it
found
that
them
were
potent
agents
against
nosocomial
(Klebsiela
pneumoniae,
Proteus
mirabilis,
Salmonela
enterica,
Enterococcus
faecalis,
epidermis
Pseudomonas
aeruginosa).
Antibiofouling
testing
indicated
CPDs/PU
eradicated
almost
completely
biofilms
aeruginosa
Staphylococcus
aureus
about
50%
Escherichia
coli
biofilms.
Carbohydrate-functionalized
quantum
dots
exhibit
excellent
physical
characteristics
and
enhance
the
steric
interaction
with
biological
cells
tissues.
Glycoconjugation
of
promotes
aqueous
solubility,
stability,
reduced
immunogenicity.
Carbohydrate-protein
interactions
are
involved
in
various
vital
processes
provide
insight
into
cellular
recognition,
cell-to-cell
communication,
pathogenicity,
antigen-antibody
enzymatic
action.
Quantum
fluorescent
materials
rich
mechanical
unique
optical
properties,
making
them
valuable
for
biomedical
applications.
Recent
advancements
dot
as
tools
have
led
to
development
carbohydrate-conjugated
glyco-functionalized
dots.
These
innovations
promise
application
nanocarriers,
imaging
agents,
probes,
theranostics.
This
review
provides
an
overview
glyco
nanotechnology,
emphasizing
metal-,
silicon-,
carbon-based
their
potential
uses.
We
hope
that
this
study
will
address
gap
field
a
more
precise
understanding
subject.
