Exploring Laboratory Findings in Psychotic Patients DOI Creative Commons

Ibrahim Abdul Jaleel Yamani

African Journal of Biomedical Research, Journal Year: 2024, Volume and Issue: unknown, P. 2705 - 2710

Published: Oct. 15, 2024

psychoses lose touch with reality. Laboratory findings are widely used in the differential diagnosis, treatment, and outcome monitoring of psychotic patients. Study objectives: The main objectives this review study were to explore if laboratory can participate diagnosis progress Psychotic disorders. Methods: Literature was reviewed collect appropriate cited articles field. searching engines including ScienceDirect, PubMed, Googlescholar. selected summarized. research team organized data prepared final manuscript. Results: showed that there several biochemical be utilized monitor progression diseases. These tests include, but not restricted to, magnesium, vitamin D, heavy metals such as mercury, lead, cadmium. Conclusion: Although great importance diseases, these may conclusive Further future studies required find more in-depth tests.

Language: Английский

Clinical efficacy and cost‐effectiveness of metformin in different patient populations: A narrative review of real‐world evidence DOI Creative Commons
Anna Solini, Domenico Tricò

Diabetes Obesity and Metabolism, Journal Year: 2024, Volume and Issue: 26(S3), P. 20 - 30

Published: June 28, 2024

Over the past two decades, diabetes pharmacopoeia has flourished, with new drugs that, on top of their glucose-lowering efficacy, have been shown to protect heart and kidney. Despite these opportunities, metformin retains a pivotal role among agents. As one few available insulin sensitizers, is an effective, safe, overall well-tolerated drug backed by over 60 years clinical experience, including evidence for potential benefits beyond glucose reduction across different ages, sexes, genetic backgrounds, geographical areas, stages disease. Although there some discussion whether offers most effective front-line option in newly diagnosed type 2 (T2D), it remains natural companion all other Furthermore, comes at very low cost and, as such, extremely high cost-effectiveness, particularly given serious economic burden associated complications. This financial advantage relevant resource-constrained healthcare systems, where affordability may be instrumental implementing treatment evergrowing number individuals. We present here compelling real-world support efficacy cost-effectiveness patient populations, highlighting areas more population-based studies are needed further incorporate consolidate its use pharmacological management T2D.

Language: Английский

Citations

4
Disease Clusters in Multimorbidity: A Systematic Review and Meta-Analysis DOI
Jennifer K. Ferris,

Lean Fiedeldey,

Boah Kim

et al.

Published: Jan. 1, 2025

Language: Английский

Citations

0
Temporal change in multimorbidity prevalence, clustering patterns, and the association with mortality: findings from the China Kadoorie Biobank study in Jiangsu Province DOI Creative Commons
Hao Yu, Ran Tao, Jinyi Zhou

et al.

Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 12

Published: April 18, 2024

Objectives The characteristics of multimorbidity in the Chinese population are currently unclear. We aimed to determine temporal change prevalence, clustering patterns, and association with mortality from all causes four major chronic diseases. Methods This study analyzed data China Kadoorie Biobank performed Wuzhong District, Jiangsu Province. A total 53,269 participants aged 30–79 years were recruited between 2004 2008. New diagnoses 15 diseases death events collected during mean follow-up 10.9 years. Yule's Q cluster analysis method was used patterns multimorbidity. Cox proportional hazards model estimate associations mortalities. Results overall prevalence rate 21.1% at baseline 27.7% end follow-up. Multimorbidity increased more rapidly individuals who had a higher risk baseline. Three main identified: (i) cardiometabolic (diabetes, coronary heart disease, stroke, hypertension), (ii) respiratory (tuberculosis, asthma, obstructive pulmonary disease), (iii) mental, kidney arthritis (neurasthenia, psychiatric disorders, rheumatoid arthritis). There 3,433 deaths by 24% each additional disease [hazard ratio (HR) = 1.24, 95% confidence interval (CI) 1.20–1.29]. Compared those without baseline, both associated Cardiometabolic additionally cardiovascular diabetes, HRs 2.64 (95% CI 2.19–3.19) 28.19 14.85–53.51), respectively. Respiratory mortality, an HR 9.76 6.22–15.31). Conclusion has substantially over past decade. revealed that have significantly rates. These findings indicate need consider high-risk populations provide local evidence for intervention strategies health management economically developed regions.

Language: Английский

Citations

2
COMORBIDITY IN ONCOLOGY: MODERN CHALLENGES AND THE SEARCH FOR WAYS TO SOLVE THE PROBLEM DOI Creative Commons
O.V. Drobotun,

Nikolai N. Kolotilov,

V.F. Konovalenko

et al.

Clinical and Preventive Medicine, Journal Year: 2024, Volume and Issue: 3, P. 132 - 141

Published: May 8, 2024

Introduction. The article is devoted to the current problem of modern oncology – increasing treatment effectiveness cancer patients with comorbidities. Comorbidity accompanied by higher rates mortality, disability, side effects treatment, increased use patient's body resources, and lower quality life. aim study. To develop a method recurrence prevention after bone lesions resection replacement surgery for malignant primary tumors, which would ensure longer duration 1st recurrence-free period in Materials methods. study included control group consisting 27 who underwent removal tumors pelvis extremities. 25 biomin pelvic bones limbs, as well neuropeptide therapy drug dalargin. Results. obtained data testify proposed dalargin: compaction structure compact spongy tissues an increase their heterogeneity have been established. Under influence dalargin, interface, characteristic intact tissue, reorganized, accordingly, restoration strength observed. 12 months operation, density main practically recovered values typical limb (p<0.01). No such recovery was observed group. Within 11 23 months, 10 had tumor recurrences. Instead, group, analysis results revealed following: within 21 only 1 patient tumor. Conclusions. Neuropeptide Dalargin helps relapse-free polymorbidity. integration into therapeutic protocol dalargin allows complex improve prognosis course disease.

Language: Английский

Citations

1
Geoenvironmental variables as causal cofactors of diseases of unknown etiology DOI
Theophilus Clavell Davies

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 81 - 193

Published: Jan. 1, 2024

Language: Английский

Citations

0
Exploring Laboratory Findings in Psychotic Patients DOI Creative Commons

Ibrahim Abdul Jaleel Yamani

African Journal of Biomedical Research, Journal Year: 2024, Volume and Issue: unknown, P. 2705 - 2710

Published: Oct. 15, 2024

psychoses lose touch with reality. Laboratory findings are widely used in the differential diagnosis, treatment, and outcome monitoring of psychotic patients. Study objectives: The main objectives this review study were to explore if laboratory can participate diagnosis progress Psychotic disorders. Methods: Literature was reviewed collect appropriate cited articles field. searching engines including ScienceDirect, PubMed, Googlescholar. selected summarized. research team organized data prepared final manuscript. Results: showed that there several biochemical be utilized monitor progression diseases. These tests include, but not restricted to, magnesium, vitamin D, heavy metals such as mercury, lead, cadmium. Conclusion: Although great importance diseases, these may conclusive Further future studies required find more in-depth tests.

Language: Английский

Citations

0