Parental status and gender are associated with differences in Tdap vaccination rates among United States adults
Vaccine,
Journal Year:
2025,
Volume and Issue:
52, P. 126901 - 126901
Published: Feb. 24, 2025
Language: Английский
Make America Healthy Again as a Clinical Practice Guideline: Let the Recommendation Classification System Speak for Itself
The American Journal of Medicine,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 1, 2025
Language: Английский
Comprehensive Clustering Analysis and Profiling of COVID-19 Vaccine Hesitancy and Related Factors across U.S. Counties: Insights for Future Pandemic Responses
Healthcare,
Journal Year:
2024,
Volume and Issue:
12(15), P. 1458 - 1458
Published: July 23, 2024
This
study
employs
comprehensive
clustering
analysis
to
examine
COVID-19
vaccine
hesitancy
and
related
socio-demographic
factors
across
U.S.
counties,
using
the
collected
curated
data
from
Johns
Hopkins
University.
Utilizing
K-Means
hierarchical
clustering,
we
identify
five
distinct
clusters
characterized
by
varying
levels
of
hesitancy,
MMR
vaccination
coverage,
population
demographics,
political
affiliations.
Principal
Component
Analysis
(PCA)
was
conducted
reduce
dimensionality,
key
variables
were
selected
based
on
their
contribution
cumulative
explained
variance.
Our
reveals
significant
geographic
demographic
patterns
in
providing
valuable
insights
for
public
health
strategies
future
pandemic
responses.
Geospatial
highlights
distribution
United
States,
indicating
areas
with
high
low
hesitancy.
In
addition,
multiple
regression
analyses
within
each
cluster
predictors
corresponding
county
clusters,
emphasizing
importance
socio-economic
factors.
The
findings
underscore
need
targeted
interventions
tailored
communication
address
States
and,
potentially,
globe.
Language: Английский
Estimation of the Eligible Population For Resmetirom Among Adults in the United States for Treatment of Non-Cirrhotic NASH with Moderate-to-Advanced Liver Fibrosis
Advances in Therapy,
Journal Year:
2024,
Volume and Issue:
41(11), P. 4172 - 4190
Published: Sept. 18, 2024
As
of
March
2024,
resmetirom
is
the
first
and
only
therapy
approved
in
United
States
(US)
for
treatment
adults
with
non-cirrhotic
nonalcoholic
steatohepatitis
(NASH)
moderate-to-advanced
liver
fibrosis
(MALF)
consistent
stages
F2/F3
fibrosis.
Estimates
diagnosed,
treatment-eligible
NASH
population
are
poorly
understood
due
to
diagnostic
variability.
This
study
provides
a
contemporary
estimate
size
US
population.
Language: Английский
Adherence to COVID‐19 vaccination recommendations and vaccine hesitancy in US blood donors
Transfusion,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 21, 2024
Abstract
Background
General
vaccination
rates
have
been
falling
globally
despite
unequivocal
health
benefits.
Noncompliance
can
result
from
access
barriers
and/or
hesitant
attitudes.
Few
studies
investigated
the
prevalence
and
determinants
of
noncompliance
with
COVID‐19
in
blood
donors.
Methods
We
surveyed
donors
on
infection
history,
motivations
for
vaccination,
comorbidities.
estimate
noncompliance,
hesitancy
toward
vaccines,
investigate
associated
factors
using
multivariable
models.
Results
From
December
2021
to
2022,
33,610
survey
respondents
were
included.
Of
these,
24%
had
not
vaccinated
or
missing
information,
99%
those
who
reported
reasons
being
unvaccinated
declared
at
least
one
three
attitudes
presented
(safety
concerns;
personal/cultural/religious
beliefs;
young
worrying
about
vaccinated).
Among
noncompliant
donors,
<2%
barriers.
In
model
addressing
vaccine
younger
age,
male
gender,
White/Caucasian
race,
absence
comorbidities,
residency
a
State
less
restrictive
policies,
living
micropolitan
rural
areas
identified
as
significant
predictors.
Younger
age
race
independently
among
Conclusions
found
high
mostly
driven
by
hesitancy.
Understanding
adherence
donors—a
relatively
highly
educated
healthy
population,
good
healthcare
usually
motivated
altruism—could
provide
key
information
that
may
be
harder
overcome.
Language: Английский
Association Between County-Level Social Vulnerability and Vaccine-Related Attitudes and Hesitancy Toward COVID-19 Vaccination in the United States
Vaccines,
Journal Year:
2024,
Volume and Issue:
12(12), P. 1368 - 1368
Published: Dec. 3, 2024
Background/Objectives:
Understanding
attitudes
and
behaviors
related
to
vaccination
is
critical
for
enhancing
COVID-19
acceptance
reducing
disparities
in
coverage.
This
study
examines
vaccine-related
vaccine
hesitancy
the
United
States
relation
community-level
social
vulnerability.
Methods:
analyzed
cross-sectional
national
surveys
conducted
repeatedly
between
July
2020
August
2021
(n
=
6716).
We
assessed
association
county-level
vulnerability
general
attitudes,
as
well
hesitancy.
developed
Poisson
models
with
robust
variance
estimation.
The
analysis
also
included
of
county
parental
Results:
Living
counties
high
Socioeconomic
Status
was
associated
less
support
(adjusted
Prevalence
Ratio
(aPR)
1.10;
95%
CI
1.05–1.14)
residing
Household
Characteristics
higher
likelihood
(aPR
1.13;
1.07–1.20).
In
contrast,
Racial
Ethnic
Minority
more
positive
toward
vaccines
0.91;
0.88–0.94)
lower
both
themselves
0.81;
0.76–0.87)
children
0.84;
0.75–0.94),
after
adjusting
sociodemographic
factors.
Conclusions:
Our
highlights
importance
addressing
vulnerabilities
socioeconomic
status
household
characteristics
reduce
perceptions
socially
vulnerable
populations.
findings
provide
evidence
targeted
public
health
interventions
at
community
level.
They
demonstrate
that
relationship
varies
across
different
components.
Language: Английский