Frontiers in Cardiovascular Medicine,
Journal Year:
2024,
Volume and Issue:
11
Published: Nov. 18, 2024
Background
Weight-adjusted
waist
circumference
index
(WWI)
is
a
novel
related
to
obesity
and
has
been
associated
with
the
risk
prognosis
of
several
diseases.
The
aim
study
was
determine
association
between
WWI
myocardial
infarction.
Methods
analyzed
cross-sectional
data
from
31,535
participants
derived
1999–2014
National
Health
Nutrition
Examination
Survey
(NHANES)
dataset.
Multiple
logistic
regression
restricted
cubic
spline
(RCS)
analyses
were
conducted
assess
both
linear
nonlinear
associations
Subgroup
interaction
tests
also
performed.
Results
Among
analyzed,
1,449
(4.82%)
had
experienced
fully
adjusted
models
demonstrated
positive
infarction
[odds
ratio
(OR)
=
1.34,
95%
confidence
interval
(CI):
1.13–1.58].
Individuals
in
highest
quartile
81%
more
likely
suffer
compared
those
lowest
(OR
1.81,
CI:
1.24–2.63).
analysis
employing
modeling
indicated
correlation
1.29
times
higher
when
below
10.97
cm/√kg
2.29,
1.37–3.84).
When
exceeded
cm/√kg,
upward
trend
significantly
slowed
increasing
1.26,
95%CI:1.03–1.56).
A
threshold
value
greater
than
11.15
identified
for
predicting
infarction,
outperforming
body
mass
(BMI).
revealed
that
impact
on
varied
across
different
populations.
Interaction
significant
interactions
incidence
age,
hypertension,
coronary
heart
disease,
angina
pectoris,
stroke
(
P
<0.05),
but
not
gender,
race,
obesity,
diabetes,
or
prediabetes
failure
>0.05).
Conclusions
findings
suggest
there
non-linear
We
recommend
incorporating
into
routine
physical
examinations
cardiovascular
screening
as
an
early
warning
mechanism.
This
may
facilitate
identification
high-risk
individuals
promote
earlier
preventive
interventions.
Clinical Cosmetic and Investigational Dermatology,
Journal Year:
2025,
Volume and Issue:
Volume 18, P. 7 - 18
Published: Jan. 1, 2025
Purpose:
Psoriasis
is
associated
with
obesity,
which
in
turn
linked
to
increased
mortality
risk.
Therefore,
we
undertook
a
cohort
study
utilizing
data
from
the
National
Health
and
Nutrition
Examination
Survey
(NHANES)
examine
impact
of
weight-adjusted
waist
index
(WWI)
on
likelihood
all-cause
psoriasis
individuals.
Patients
Methods:
This
utilized
investigate
influence
WWI
probability
A
retrospective
analysis
included
19,919
participants
aged
18
80
years,
or
without
psoriasis.
The
primary
endpoint
studied
was
all-encompassing
up
December
2019.
interplay
between
analyzed
through
multivariable
logistic
regression
techniques.
Survival
probabilities
were
assessed
employing
Kaplan-Meier
curves
Cox
analyses.
Results:
Out
subjects
that
eventually
included,
522
had
found
be
significantly
positively
correlated.
significant
correlation
an
incremental
unit
increase
63%
risk
patients
(HR
=
1.63,
95%
CI
1.02–
2.61).
Subgroup
analyses
demonstrated
consistent
findings
within
population.
These
suggest
independent
mortality.
Conclusion:
Our
investigation
revealed
there
strong
positive
US
adults.
For
those
psoriasis,
managing
WWI,
crucial.
Keywords:
mortality,
NHANES
Frontiers in Nutrition,
Journal Year:
2025,
Volume and Issue:
12
Published: Feb. 12, 2025
Obesity
is
a
significant
risk
factor
for
peripheral
arterial
disease
(PAD).
The
weight-adjusted
waist
index
(WWI)
novel
obesity
metric
that
better
reflects
abdominal
than
traditional
body
mass
(BMI).
However,
research
on
the
relationship
between
WWI
and
PAD
remains
scarce.
Relevant
data
from
NHANES
1999-2004
were
selected.
Multiple
logistic
regression
restricted
cubic
spline
(RCS)
analyses
used
to
assess
of
PAD.
Additionally,
area
under
curve
(AUC)
receiver
operating
characteristic
(ROC)
was
evaluate
predictive
ability
A
total
5,686
participants
included
in
study,
whom
476
had
5,210
did
not.
results
multiple
showed
significantly
positively
associated
with
after
full
adjustment
covariates
(OR:
1.407,
95%
CI:
1.100-1.799).
compared
first
quartile
WWI,
increased
second
2.042,
1.333-3.129),
third
2.134,
1.354-3.364),
fourth
2.491,
1.435-4.325).
ROC
AUC
value
0.697,
while
BMI
0.520.
Compared
BMI,
has
There
positive
correlation
For
individuals
high
efforts
should
be
made
reduce
prevent
onset
Frontiers in Cardiovascular Medicine,
Journal Year:
2025,
Volume and Issue:
12
Published: Feb. 10, 2025
Background
Weight-adjusted-waist
(WWI)
is
a
novel
indicator
of
obesity
that
reflects
the
degree
central
in
human
body.
Objectives
The
study
aimed
to
explore
relationship
between
WWI
and
mortality
hypertensive
individuals.
Methods
Cross-sectional
data
from
2001–2018
National
Health
Nutrition
Examination
Survey
(NHANES)
dataset
were
used
this
study.
was
assessed
using
weighted
Cox
proportional
risk
model;
nonlinear
explored
restricted
cubic
splines.
robustness
results
verified
by
subgroup
sensitivity
analyses.
Results
A
cohort
11,556
people
with
diagnosis
hypertension
included
As
continuous
variable,
linked
higher
rates
all-cause
(HR
=
1.23,
95%
CI
1.14,
1.33)
cardiovascular
disease
(CVD)
1.43,
1.66)
Model
3
adjusted
for
variables.
Using
as
tertile
categorical
individuals
highest
had
33%
death
1.33,
1.56)
65%
CVD
1.65,
1.19,
2.27)
than
lowest
tertile.
According
analysis,
almost
all
groups
showed
consistent
positive
correlation
related
CVD.
Conclusion
In
adults
hypertension,
there
association
mortality.
medRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 13, 2025
Abstract
Objective
Chronic
kidney
disease
(CKD)
patients
face
significant
mortality
risks,
and
remnant
cholesterol
(RC)
may
be
a
critical
prognostic
indicator.
This
study
aimed
to
explore
the
association
between
RC
all-cause
cardiovascular
risks
in
CKD
patients.
Methods
prospective
cohort
utilized
data
from
National
Health
Nutrition
Examination
Survey
(NHANES)
2001-2018,
including
1,606
aged
over
60.
Cox
proportional
hazards
models
were
employed
assess
mortality,
with
multi-model
adjustments
subgroup
analyses.
Results
During
93.9
months
of
follow-up,
932
events
(58.0%)
283
(17.6%)
observed.
Each
logarithmic
unit
increase
was
associated
41%
reduction
risk
(adjusted
HR:
0.59,
95%
CI:
0.40-0.87,
P=0.0079).
Subgroup
analyses
revealed
significantly
reduced
women
(HR=0.71),
hypertensive
(HR=0.75),
type
2
diabetes
(HR=0.66).
Conclusion
In
patients,
is
risk,
providing
new
perspective
for
individualized
assessment.
Scientific Reports,
Journal Year:
2025,
Volume and Issue:
15(1)
Published: March 12, 2025
Cardiometabolic
Syndrome
(CMS)
is
associated
with
increased
risks
of
cardiovascular
disease,
type
2
diabetes
mellitus,
and
all-cause
mortality.
The
Weight-Adjusted
Waist
Circumference
Index
(WWI)
has
emerged
as
a
novel
metric
for
assessing
obesity
its
health
implications.
To
investigate
the
relationship
between
WWI
mortality
in
CMS
patients,
considering
mediating
role
inflammatory
markers.
study
analyzed
National
Health
Nutrition
Examination
Survey
(NHANES)
data
from
2003
to
2018
identified
6506
patients
CMS.
was
calculated
square
root
waist
circumference
(cm)
divided
by
weight
(kg).
Mortality
were
correlated
Death
(NDI).
Cox
regression
models,
adjusted
demographic
clinical
covariates,
assessed
effect
on
cause-specific
Finally,
markers
explored
using
mediation
analysis.
observed
positive
linear
association
all-cause,
cardiovascular,
diabetes-related
mortalities
among
patients.
After
adjusting
confounders,
remained
significant
predictor
Mediation
analysis
revealed
that
markers,
particularly
neutrophil
systemic
immune-inflammation
index
(SII),
significantly
mediated
an
independent
inflammation
potentially
linking
risk.
These
findings
may
inform
risk
assessment
management
strategies
Scientific Reports,
Journal Year:
2025,
Volume and Issue:
15(1)
Published: April 18, 2025
To
explore
the
associations
of
central
obesity
indicators
including
waist
circumference
(WC),
waist-to-height
ratio
(WHtR),
and
weight-adjusted
index
(WWI)
with
impairment
basic
activities
daily
living
(BADL)
instrumental
(IADL)
among
middle-aged
elderly
population
in
China.
This
prospective
study
used
baseline
data
from
2011
follow-up
data,
involving
6440
9646
participants,
respectively.
Binary
logistic
regression
analysis
was
to
assess
relationships.
Restricted
cubic
spline
(RCS)
curve
also
analyze
correlation
trends.
Stratified
analyses
were
performed
identify
potential
differences.
Receiver
operating
characteristic
curves
plotted
evaluate
predictive
value
each
indicator.
WC
(OR
=
1.01,
95%
CI:1.01-1.02),
WHtR
1.21,
CI
1.09-1.33),
WWI
1.10,
CI:1.02-1.19)
significantly
associated
BADL
impairment.
Only
1.16,
95%CI:1.09-1.23)
IADL
WC,
linearly
while
The
risk
association
between
stronger
drinking
individuals
males.
In
participants
a
BMI
less
than
24
kg/m²
who
had
received
high
school
education
or
above,
increase
accompanied
by
more
significant
ability
is
higher
that
WHtR,
AUC
values
0.597
0.615.
WWI,
as
comprehensive
indicator
obesity,
may
be
useful
comprehensively
identifying
early
activity
population.
Frontiers in Public Health,
Journal Year:
2025,
Volume and Issue:
13
Published: April 22, 2025
Cardiopulmonary
fitness
is
associated
with
several
physical
health
indicators
in
children
and
adolescents
has
shown
a
downward
trend
recent
years.
The
20-m
SRT
received
widespread
attention
from
scholars
as
recognized
indirect
measure
for
evaluating
cardiopulmonary
fitness.
However,
few
studies
have
analyzed
the
association
between
weight-adjusted
waist
index
(WWI),
novel
indicator,
Chinese
adolescents.
In
this
study,
41,523
aged
6-17
years
China
were
assessed
weight,
circumference,
SRT,
related
covariates.
One-way
ANOVA,
LSD,
curvilinear
regression
analyses
used
to
analyze
associations
that
existed
WWI
SRT.
Comparison
of
scores
among
different
ages
showed
statistically
significant
differences
(F-values
2179.297
4956.795,
respectively,
p
<
0.001).
Overall,
both
boys
girls
general
increasing
age,
maximum
48.78
laps
31.17
age
group
15-17
years,
respectively.
(p
0.001)
when
compared
groups.
Both
lower
higher
resulted
scores,
more
significantly
girls.
There
an
inverted
"U"
curve
relationship
reflected
genders
future,
we
should
ensure
within
reasonable
range
better
promote
Frontiers in Aging Neuroscience,
Journal Year:
2024,
Volume and Issue:
16
Published: Nov. 29, 2024
It
is
crucial
to
identify
biomarkers
that
influence
the
aging
process
and
associated
health
risks,
given
growing
severity
of
global
population
issue.
The
objectives
our
research
were
evaluate
cardiac
metabolic
index
(CMI)
as
a
novel
biomarker
for
identifying
individuals
at
increased
risk
accelerated
biological
assess
its
use
in
guiding
preventive
strategies
aging-related
risks.